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Our top choices for Santa Cruz hotels

Amazon Aeroporto Hotel

Amazon Aeroporto Hotel
3.0 star property
9.3 km from Santa Cruz
9.4 out of 10, Exceptional, (760 reviews)
"Very wonderful and staff extremely professional and helpful"
United States
Steven
The price is ฿3,686
฿3,870 total
includes taxes & fees
18 Mar - 19 Mar
Amazon Aeroporto Hotel

Hotel alameda

Hotel alameda
2.5 star property
5.9 km from Santa Cruz
10.0 out of 10, Exceptional, (3 reviews)
"Localização excelente, muito conveniente para quem viaja a trabalho. Quartos amplos, limpos e equipados. O café da manhã é bem completo. Ótimo custo-benefício."
Brazil
Urivelton
The price is ฿1,213
฿1,274 total
includes taxes & fees
17 Mar - 18 Mar
Hotel alameda

HITS PANTANAL HOTEL AEROPORTO

HITS PANTANAL HOTEL AEROPORTO
3.5 star property
9.7 km from Santa Cruz
8.4 out of 10, Very good, (464 reviews)
"A nice hotel, friendly staff, adjacent to a shopping mall, close to the airport but very quiet, a very efficient transfer service to to pick me up from the airport. But what really stands out is the amazing swimming pool. One of the best pools I encountered at a hotel for swimming laps! I can definately recommend this hotel."
United States
Rob
The price is ฿1,600
฿1,680 total
includes taxes & fees
20 Mar - 21 Mar
HITS PANTANAL HOTEL AEROPORTO

Hotel Deville Prime Cuiabá

Hotel Deville Prime Cuiabá
4.0 star property
6.3 km from Santa Cruz
9.2 out of 10, Wonderful, (685 reviews)
"Great hotel"
United States
Jean
The price is ฿3,405
฿3,847 total
includes taxes & fees
12 Apr - 13 Apr
Hotel Deville Prime Cuiabá

Loft completo e climatizado

Loft completo e climatizado
2.5 star property
Dom Aquino, 5.1 km from Santa Cruz
8.8 out of 10, Excellent, (5 reviews)
"No geral, a estadia foi excelente. O wifi não funcionou no loft em que estava e havia um pouco de poeira e uns insetos querendo partilhar a acomodação, mas nada que me atrapalhou. A anfitriã foi excelente e atendeu as minhas solicitações, na medida do possível."
Brazil
Ricardo
The price is ฿1,260
฿1,298 total
includes taxes & fees
17 Mar - 18 Mar
Loft completo e climatizado

Hotel Marion Pantanal

Hotel Marion Pantanal
3.0 star property
16.8 km from Santa Cruz
7.6 out of 10, Good, (34 reviews)
"Gfff"
United States
Zyad
The price is ฿1,329
฿1,455 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Marion Pantanal

Hotel 365

Hotel 365
3.0 star property
4.6 km from Santa Cruz
8.2 out of 10, Very good, (106 reviews)
"Staff was very very friendly, Breakfast was good, would recommend and will stay here again when I travel to Cuiaba in the future."
United States
Prince Sebastian Ragland
The price is ฿1,401
฿1,587 total
includes taxes & fees
27 Mar - 28 Mar
Hotel 365

Hotel Itamaraty

Hotel Itamaraty
3.0 star property
18.8 km from Santa Cruz
8.4 out of 10, Very good, (21 reviews)
"It is a very old fashioned hotel . It’s smells bad . Terrible bathroom and it stinks vey badly. Bed was not made for 4 people. Sheets was used before. Toiletries was very limited. Breakfast was good - but kitchen conditions was not good . In general I do not recommend this hotel at all . "
United Kingdom
Luciene
The price is ฿1,404
฿1,474 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Itamaraty

Hotel Gran Odara

Hotel Gran Odara
4.0 star property
7.6 km from Santa Cruz
9.4 out of 10, Exceptional, (656 reviews)
"Great breakfast and comfortable bed."
United States
Stephen
The price is ฿3,427
฿3,873 total
includes taxes & fees
22 Mar - 23 Mar
Hotel Gran Odara

CRYPTOS HOTEL

CRYPTOS HOTEL
3.0 star property
14 km from Santa Cruz
The price is ฿1,086
฿1,140 total
includes taxes & fees
17 Mar - 18 Mar
CRYPTOS HOTEL

Hotel Portal da Amazônia

Hotel Portal da Amazônia
3.0 star property
9.2 km from Santa Cruz
9.0 out of 10, Wonderful, (46 reviews)
"The staff were friendly and helpful and the room was clean."
United States
Michael Christopher
The price is ฿1,802
฿1,892 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Portal da Amazônia

Fly Hotel

Fly Hotel
3.0 star property
9.5 km from Santa Cruz
8.6 out of 10, Excellent, (223 reviews)
"We had an amazing experience at Fly Hotel! Beds were very comfortable and the staff were very helpful and really nice!!!"
United States
Leliane
The price is ฿1,820
฿1,911 total
includes taxes & fees
17 Mar - 18 Mar
Fly Hotel

Hotel Fazenda Mato Grosso

Hotel Fazenda Mato Grosso
3.0 star property
Coxipó, 3.6 km from Santa Cruz
8.0 out of 10, Very good, (153 reviews)
"Nice hotel, lovely helpful staff . Rooms a bit tired but have everything you need. There is a decent size pool. Not close to any restaurants but there is the hotel restaurant open all day with nice food. Good breakfast. Took us about 15 mins to the airport in a quiet time of day."
United Kingdom
Lynn
Hotel Fazenda Mato Grosso

Brisas Flat Style

Brisas Flat Style
3.0 star property
Duque de Caxias, 7.3 km from Santa Cruz
9.8 out of 10, Exceptional, (106 reviews)
"Amazing!!"
United Kingdom
Wilmer Moniz
The price is ฿2,756
฿2,839 total
includes taxes & fees
23 Mar - 24 Mar
Brisas Flat Style

Roari Hotel

Roari Hotel
3.0 star property
4.8 km from Santa Cruz
8.8 out of 10, Excellent, (112 reviews)
"Equipe, Cafe da manhã, localização!"
Brazil
BRUNO
The price is ฿1,961
฿2,020 total
includes taxes & fees
17 Mar - 18 Mar
Roari Hotel

Criptos Hotel e Restaurante

Criptos Hotel e Restaurante
3.0 star property
13.7 km from Santa Cruz
Criptos Hotel e Restaurante

Hotel Sansaed

Hotel Sansaed
3.0 star property
Lixeira, 4.9 km from Santa Cruz
8.8 out of 10, Excellent, (33 reviews)
"The hotel was basic but ok."
United States
Katleen
The price is ฿2,507
฿2,583 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Sansaed

Ami Hotel

Ami Hotel
2.5 star property
9.8 km from Santa Cruz
7.2 out of 10, Good, (37 reviews)
"Custo benefício ok"
Brazil
Clelia Franciele
The price is ฿1,487
฿1,561 total
includes taxes & fees
17 Mar - 18 Mar
Ami Hotel

Delcas Hotel

Delcas Hotel
3.0 star property
Coxipó, 2.5 km from Santa Cruz
8.0 out of 10, Very good, (719 reviews)
"Breakfast was amazing!"
United States
Zoe
The price is ฿1,887
฿1,943 total
includes taxes & fees
24 Mar - 25 Mar
Delcas Hotel

Hotel Express

Hotel Express
2.5 star property
9.4 km from Santa Cruz
8.2 out of 10, Very good, (286 reviews)
"Very nice place with affordable price. Staff was kind and the place very clean"
United States
Onilo
The price is ฿1,560
฿1,638 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Express
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

São Gonçalo Beira-Rio

When in São Gonçalo Beira-Rio, you can plan a visit to Ze Bolo Flo Park and Shopping 3 Americas, some noteworthy sights in the nearby area.

Coxipó

Travellers like the parks in Coxipó, and Ze Bolo Flo Park is a top attraction you might want to visit.

Centro Político Administrativo

Parks and riverfront are just a few things travellers like about Centro Político Administrativo. A stop by Massairo Okamura Park is also recommended if you've got time to explore the area.

UFMT

Travellers like the museums in UFMT, and UFMT Zoo is a top attraction you might want to visit.

Central North

You'll enjoy the waterfalls and riverfront in Central North. You might want to make time for a stop at Historical Museum of Mato Grosso or Cine Teatro Cuiaba.

Top Santa Cruz Hotel Reviews

Frequently asked questions

What is Santa Cruz like?
Travellers will be sure to find plenty to entertain them in Cuiabá's Santa Cruz neighbourhood.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, the majority of hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best deals in Santa Cruz.
What is there to do in this Cuiabá neighbourhood?
UFMT Zoo, Museum of the Indigenous People and Rondon Museum are just a few of the places to visit in and around Santa Cruz. While you're out sightseeing, Shopping 3 Americas and Ze Bolo Flo Park are a couple of additional sights to visit in Cuiabá.