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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (100 reviews)
"Always an amazing stay"
United States
chris
The price is ฿2,966
฿4,264 total
includes taxes & fees
15 Jul - 16 Jul
Casco View Apartments

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ฿922
฿1,014 total
includes taxes & fees
11 Jul - 12 Jul
Hostal La Cigarra

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ฿901
฿991 total
includes taxes & fees
7 Aug - 8 Aug
Hotel Riazor

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ฿2,249
฿3,395 total
includes taxes & fees
12 Jul - 13 Jul
La Manzana Barrio Vivo by Wynwood

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (195 reviews)
"Very good ."
United States
Denice
The price is ฿976
฿3,075 total
includes taxes & fees
10 Jul - 11 Jul
Hotel República

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ฿1,228
฿1,351 total
includes taxes & fees
10 Jul - 11 Jul
ART CASCO The Hotel

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,816 reviews)
"Very beautiful and convenient in every way possible."
United States
Mohanie
The price is ฿3,940
฿4,334 total
includes taxes & fees
20 Jul - 21 Jul
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,618 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is ฿4,385
฿5,044 total
includes taxes & fees
9 Aug - 10 Aug
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (79 reviews)
"Really good food, nice staff it was the best service! "
United States
junier
The price is ฿5,337
฿5,871 total
includes taxes & fees
14 Jul - 15 Jul
Villa Caprichosa

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (146 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is ฿3,412
฿4,429 total
includes taxes & fees
10 Jul - 11 Jul
ORHO Hotel Boutique 15 Minutes from PTY Airport

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (245 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is ฿4,237
฿4,660 total
includes taxes & fees
15 Jul - 16 Jul
Renaissance Panama City Hotel

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
24.7 km from Santa Ana
8.0 out of 10, Very good, (785 reviews)
"Great place to stay."
United States
Oscar
The price is ฿4,774
฿5,251 total
includes taxes & fees
10 Jul - 11 Jul
Gamboa Rainforest Reserve

The District Hotel Panama

The District Hotel Panama
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
7.4 out of 10, Good, (9 reviews)
"Feoooo y caro"
United States
Rony
The price is ฿2,602
฿2,862 total
includes taxes & fees
14 Jul - 15 Jul
The District Hotel Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,710 reviews)
"Breakfast was amazing pool was warm and relaxing"
United States
Vicenta
The price is ฿4,398
฿4,838 total
includes taxes & fees
8 Aug - 9 Aug
Hotel Riu Plaza Panama

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (317 reviews)
"This condo was amazing! We will definitely come back every year to Panama and stay at Arcadia condo suites."
United States
Jose
The price is ฿3,163
฿3,700 total
includes taxes & fees
12 Jul - 13 Jul
Arcadia Condo Suites

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (441 reviews)
"Very nice small hotel, comfortable excellent location on Amador Causeway. Close to Albrook Mall, Casco, Viejo…"
United States
David
The price is ฿2,567
฿2,824 total
includes taxes & fees
14 Jul - 15 Jul
The Beach House

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,006 reviews)
"The hotel is good, love the quiet atmosphere it have some times."
United States
Carol
The price is ฿2,852
฿3,137 total
includes taxes & fees
21 Jul - 22 Jul
Radisson Hotel Panama Canal

Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista, 3 km from Santa Ana
10.0 out of 10, Exceptional, (1 review)
"Amazing. Right next to Hilton on balboa."
United States
Abdullah
The price is ฿3,483
฿3,831 total
includes taxes & fees
3 Aug - 4 Aug
Yoo Panama Luxury Ocean View Apartment

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
9.6 out of 10, Exceptional, (363 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
The price is ฿6,401
฿7,041 total
includes taxes & fees
19 Jul - 20 Jul
Hyatt Regency Panama City

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.4 out of 10, Very good, (1,585 reviews)
"The staff was very helpful the hotel was nice and clean. Wonderful hotel I would definitely recommend"
United States
Natalia
The price is ฿4,435
฿4,879 total
includes taxes & fees
30 Jul - 31 Jul
Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
100 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
18 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
195 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Pacific Center while you're in town.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Culture: Santa Ana offers a rich tapestry of history and culture, highlighted by the Santa Ana Church and local museums.
  • Free Walking Tours: Explore the area through engaging walking tours that showcase its vibrant streets and historical significance.
  • Family-Friendly Activities: The neighbourhood is perfect for families, with numerous parks and leisure options nearby.
  • Diverse Accommodations: Enjoy a variety of lodging options, from hotels to charming vacation rentals, catering to all preferences.
  • Relaxing Atmosphere: Santa Ana boasts a welcoming vibe, ideal for unwinding while exploring the local dining scene.

Find great hotels near Santa Ana

Discover a range of delightful accommodations in Santa Ana, Panama City, offering both hotel and apartment options. Whether you seek a pet-friendly retreat, a business-friendly environment, or a charming vacation rental, Santa Ana caters to diverse traveller needs. Explore popular choices such as Hotel El Panama and various Panama City hotels, ensuring a memorable stay in this vibrant area of Panamá Province.

  • Central Hotel Panama Casco Viejo: A charming 4-star hotel, Central Hotel Panama Casco Viejo boasts a guest rating of 9.2 out of 10. Located 805m from Santa Ana, this hotel exudes a romantic and spa-themed atmosphere, making it ideal for couples seeking a serene getaway. Guests can indulge in romance packages, featuring amenities like 24-hour room service and Champagne Service. For relaxation, the hotel offers a full spa experience, including outdoor pools and a steam room, perfect for unwinding after a day of exploration. The central location adds to its appeal, allowing easy access to the vibrant city life.
  • American Trade Hotel: Rated 4.5 stars with a guest rating of 9.4 out of 10, American Trade Hotel is situated 644m from Santa Ana. This accommodation is tailored for families and adventure seekers alike, offering recreational activities such as hiking, biking, and nearby scooter rentals. The hotel also provides child-friendly amenities, ensuring a comfortable stay for families. Guests can enjoy romantic dining with garden views and benefit from spa services and outdoor pools, making it a versatile choice for both family fun and intimate escapes.
  • Sofitel Legend Casco Viejo, Panama City: This luxurious 5-star hotel, with an impressive guest rating of 9.8 out of 10, is located 1km from Santa Ana. Sofitel Legend Casco Viejo is designed for those seeking a premium spa experience or business travel. Guests can immerse themselves in relaxation with an array of spa services, including hot stone massages and outdoor treatment rooms, alongside a stunning outdoor pool. The elegant setting and refined service create an atmosphere of sophistication, making it a distinguished choice for discerning travellers.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panama City, offers an inviting blend of family-friendly activities and a lively atmosphere. Visitors can immerse themselves in the welcoming Panamanian vibe, exploring nearby districts that boast relaxing parks and luxurious dining options. With its mix of business and leisure, Santa Ana is the perfect base to discover the best of Panamá Province, ensuring a delightful experience for all types of travellers.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis that offers a unique blend of modernity and tradition. Situated in the heart of the country, it serves as a gateway to various attractions, including shopping centres and scenic parks. With a steady influx of visitors throughout the year, Panama City is particularly lively in January, July, and September. Tourists flock here for family-friendly activities, business events, and urban exploration. Be sure to visit the iconic coastline and local beaches that provide a refreshing escape from the city's hustle.
  • Casco Viejo: Located a mere 644m from Santa Ana, Casco Viejo is a historic neighbourhood that showcases the rich cultural heritage of Panama. This area attracts visitors year-round, peaking in January and during the spring months of March to April. Known for its charming streets and colonial architecture, Casco Viejo offers an array of shopping areas and resorts, making it a perfect destination for families and business travellers alike. Wander through the picturesque streets, enjoy local cuisine, and relax at nearby parks while soaking in the vibrant atmosphere.
  • Barrio Chino: Just 322m from Santa Ana, Barrio Chino is a lively neighbourhood that celebrates the cultural fusion of Panama's Chinese community. This area sees a surge in visitors from February to March and December, drawing families and business-minded tourists. The neighbourhood offers various shopping options, including centres and malls, alongside cultural landmarks such as museums and research facilities. Stroll along the bustling streets to experience the unique blend of traditions and flavours that Barrio Chino has to offer.

Things to do near Santa Ana

Shopping

In Santa Ana, visit the Albrook Mall, a large shopping centre with a variety of stores, from fashion to electronics. For a local experience, explore the nearby artisan markets, where you can find unique handcrafted souvenirs and traditional Panamanian gifts.

Recreation

The Santa Ana Wellness Centre offers holistic treatments including yoga classes and massage therapies, set in a tranquil environment. Nearby, the Parque Natural Metropolitano features scenic trails and opportunities for birdwatching, allowing visitors to reconnect with nature and rejuvenate their spirits.

Adventure

Gatun Eco Adventures offers an exhilarating zipline ropes course located 48km from Santa Ana. Experience the thrill of soaring through the treetops amidst lush landscapes, all while enjoying the vibrant outdoor atmosphere that this adventure venue provides.

Nightlife

The nightlife in Santa Ana offers a vibrant blend of local bars and lively music venues. Visit the popular La Tana for a relaxed atmosphere and enjoy cocktails, or check out Casa Góngora for live performances that showcase local talent, creating an engaging evening experience.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Ana

Santa Ana in Panama City is ideal for family, city, and business-themed holidays. Visitors can explore captivating attractions such as the Santa Ana Church and the nearby San Miguel. The area offers a delightful blend of culture, outdoor activities, and beautiful scenery, making it perfect for those seeking a rich historical experience. Don't miss the local cathedral and history museum for a deeper understanding of Santa Ana's heritage.

  • Interoceanic Canal Museum: Located a mere 805m from Santa Ana, this museum offers a fascinating insight into the history and significance of the Panama Canal. With engaging exhibits, visitors can explore the cultural impact of this engineering marvel on global trade.
  • Metropolitan Cathedral of Panama: Also situated 805m away, this stunning cathedral showcases impressive architecture and rich history. Its serene atmosphere invites contemplation, while its intricate details reflect the cultural heritage of Panama.
  • Independence Square: Just 805m from Santa Ana, this vibrant piazza is a hub of activity, surrounded by historic buildings. It's an ideal spot to experience local culture, with many events and gatherings taking place throughout the year.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Flying into Santa Ana, Panama, is convenient with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is located 3km away, with luxurious hotels such as Hilton Panama and Sofitel Legend Casco Viejo, both offering various transportation services. Balboa (BLB-Panama Pacifico Intl.) is situated 6km away, with The Westin Playa Bonita Panama as a notable hotel option. Finally, Panama City (PTY-Tocumen Intl.) is 21km away, featuring The Santa Maria, A Luxury Collection Hotel, which also provides transport services. Each airport offers easy access to the surrounding hotels, ensuring a smooth journey for visitors.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 121 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.