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Our top choices for Santa Ana hotels

Casco View Apartments
Casco View Apartments
Hostal La Cigarra
Hostal La Cigarra
La Manzana Barrio Vivo by Wynwood
La Manzana Barrio Vivo by Wynwood
Hotel República
Hotel República
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
Waymore Hotel Spa & Casino
Waymore Hotel Spa & Casino
ORHO Hotel Boutique 15 Minutes from PTY Airport
ORHO Hotel Boutique 15 Minutes from PTY Airport
Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall
Radisson Hotel Panama Canal
Radisson Hotel Panama Canal
Sheraton Grand Panama
Sheraton Grand Panama
Villa Caprichosa
Villa Caprichosa
The Beach House
The Beach House
Arcadia Condo Suites
Arcadia Condo Suites
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Albrook Inn
Albrook Inn
The Executive Hotel
The Executive HotelCompare popular hotels in Santa Ana
Where to stay in Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.
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