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Top Trending Hotels Near Santa Ana, Panama City

ART CASCO The Hotel

2.0 star property
7.2 out of 10, Good, (7)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
ART CASCO The Hotel

Casco View Apartments

3.5 star property
9.4 out of 10, Exceptional, (46)
"Great stay, would recommend."
Casco View Apartments

Hotel República

2.0 star property
6.6 out of 10, (175)
"Fantastic customer service"
Hotel República

Hostal La Cigarra

2.5 star property
7.6 out of 10, Good, (50)
"Helpful staff, secure, close to sights"
Hostal La Cigarra

Hotel Riazor

3.0 star property
3.8 out of 10, (10)
"Rough neighborhood "
Hotel Riazor

La Manzana by Wynwood House

3.0 star property
7.0 out of 10, Good, (14)
"Great hotel. Very close to Casco viejo"
The price is ฿1,828
฿2,653 total
includes taxes & fees
14 Sept - 15 Sept
La Manzana by Wynwood House

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
The price is ฿4,778
฿5,256 total
includes taxes & fees
8 Sept - 9 Sept
Room-sofa Bed Stay Rooftop Pool & Gym, A

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is ฿1,989
฿3,246 total
includes taxes & fees
11 Sept - 12 Sept
Casa Quijano 06 By Wynwood House

w Charming 1BR in Santa Ana s Best Area

2.0 star property
The price is ฿1,844
฿3,171 total
includes taxes & fees
21 Sept - 22 Sept
w Charming 1BR in Santa Ana s Best Area

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very good, (2211)
"Great hotel near the airport "
The price is ฿3,978
฿4,375 total
includes taxes & fees
28 Sept - 29 Sept
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (986)
"The hotel is so beautiful, the people are very friendly and helpful!"
The price is ฿5,272
฿5,799 total
includes taxes & fees
8 Sept - 9 Sept
Central Hotel Panama Casco Viejo

Hotel Coral Suites

3.5 star property
9.0 out of 10, Wonderful, (1001)
"Loved having a kitchen but the best thing was the wonderful housekeeping staff."
The price is ฿2,223
฿2,445 total
includes taxes & fees
8 Sept - 9 Sept
Hotel Coral Suites

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very good, (1892)
"It is convenient enough to the airport and has all the amenities you would want for a short stay. "
The price is ฿4,284
฿4,713 total
includes taxes & fees
8 Sept - 9 Sept
Riande Aeropuerto Hotel & Casino

TRYP by Wyndham Panamá Centro

3.5 star property
9.2 out of 10, Wonderful, (1003)
"Property was clean and staff specially restaurant and housekeeping very nice. "
The price is ฿2,618
฿2,879 total
includes taxes & fees
16 Sept - 17 Sept
TRYP by Wyndham Panamá Centro

La Concordia Boutique Hotel

4.0 star property
9.4 out of 10, Exceptional, (181)
"Excellent"
The price is ฿5,468
฿6,015 total
includes taxes & fees
27 Sept - 28 Sept
La Concordia Boutique Hotel

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very good, (1061)
"Had a wonderful stay the staff is very friendly and attentive "
The price is ฿4,075
฿4,482 total
includes taxes & fees
26 Sept - 27 Sept
Megapolis Hotel Panamá

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4244)
"Great buffet"
The price is ฿3,508
฿3,859 total
includes taxes & fees
8 Sept - 9 Sept
Hotel Riu Plaza Panama

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1452)
"Great Hotell , safe location , excellent Hotell staff "
The price is ฿1,877
฿2,064 total
includes taxes & fees
8 Sept - 9 Sept
Principe Hotel and Suites

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2104)
"nice place, good breakfast"
The price is ฿5,072
฿5,579 total
includes taxes & fees
8 Sept - 9 Sept
Plaza Paitilla Inn Hotel

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (606)
"I enjoyed my stay"
The price is ฿1,546
฿1,701 total
includes taxes & fees
9 Sept - 10 Sept
Hospedium Princess Hotel Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

1 out of top 10 points of interest in this area

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Ana Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 116 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.

What is there to do in this Panama City neighbourhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.