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Our top choices for Santa Ana hotels

1. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (105 reviews)
"Always an amazing stay"
United States
chris
The price is ฿2,117
฿3,309 total
includes taxes & fees
25 Aug - 26 Aug
Casco View Apartments

2. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ฿1,016
฿1,117 total
includes taxes & fees
25 Aug - 26 Aug
Hostal La Cigarra

3. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
7.6 out of 10, Good, (4 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
United States
William
The price is ฿1,176
฿1,294 total
includes taxes & fees
31 Aug - 1 Sept
Hotel Caracas - Casco Viejo

4. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.2 out of 10, (12 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ฿802
฿882 total
includes taxes & fees
29 Aug - 30 Aug
ART CASCO The Hotel

5. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is ฿956
฿3,012 total
includes taxes & fees
25 Aug - 26 Aug
Hotel República

6. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ฿2,558
฿3,712 total
includes taxes & fees
25 Aug - 26 Aug
La Manzana Barrio Vivo by Wynwood

7. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ฿882
฿970 total
includes taxes & fees
25 Aug - 26 Aug
Hotel Riazor

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is ฿3,414
฿3,756 total
includes taxes & fees
25 Aug - 26 Aug
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (442 reviews)
"Great little property in Casco Viejo."
Canada
Kerry
The price is ฿5,391
฿5,930 total
includes taxes & fees
29 Aug - 30 Aug
Hotel San Felipe

10. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.1 km from Santa Ana
9.8 out of 10, Exceptional, (729 reviews)
"It was an amazing stay! The only place we would stay in Panama City."
United States
Josh
The price is ฿11,173
฿12,290 total
includes taxes & fees
8 Sept - 9 Sept
Sofitel Legend Casco Viejo, Panama City

11. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.2 out of 10, Wonderful, (1,021 reviews)
"Love the breakfast and the rooms were amazing"
United States
querube
The price is ฿5,992
฿6,591 total
includes taxes & fees
22 Sept - 23 Sept
Central Hotel Panama Casco Viejo

12. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,885 reviews)
"Great breakfast and beautiful hotel."
United States
Lori
The price is ฿4,497
฿4,946 total
includes taxes & fees
15 Sept - 16 Sept
Hotel Riu Plaza Panama

13. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 0.9 km from Santa Ana
9.8 out of 10, Exceptional, (343 reviews)
"One of our favorite stays. Right in old town, walking distance to everything. Beautiful room, beautifal courtyard. Their on-site restaurants were also excellent."
United States
Reid
The price is ฿10,386
฿11,424 total
includes taxes & fees
17 Sept - 18 Sept
Hotel La Compañía Casco Antiguo

14. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (799 reviews)
"A lovely friendly hotel with excellent staff"
United Kingdom
Ann
The price is ฿8,025
฿8,828 total
includes taxes & fees
1 Sept - 2 Sept
American Trade Hotel

15. Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
San Felipe, 0.6 km from Santa Ana
7.6 out of 10, Good, (745 reviews)
"Beautifully decorated. Great location! Staff very helpful."
United States
Mariana
The price is ฿1,995
฿2,194 total
includes taxes & fees
24 Sept - 25 Sept
Hotel Casa Panamá

16. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (505 reviews)
"Super nice hotel, very clean and location is amazing"
United States
Boris
The price is ฿2,494
฿2,743 total
includes taxes & fees
21 Sept - 22 Sept
Hotel Magnolia Boutique

17. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,034 reviews)
"Hotel was clean and comfortable. The staff were friendly and helpful. The location is convenient if you plan to travel to Arraijan or other provinces west of the city. And the breakfast is a plus."
United States
amina
The price is ฿3,105
฿3,416 total
includes taxes & fees
22 Sept - 23 Sept
Radisson Hotel Panama Canal

18. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,236 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is ฿3,749
฿4,123 total
includes taxes & fees
6 Sept - 7 Sept
Plaza Paitilla Inn Hotel

19. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (327 reviews)
"Great Location , helpful staff"
United States
David
The price is ฿3,049
฿3,354 total
includes taxes & fees
6 Sept - 7 Sept
Tantalo Hotel

20. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,228 reviews)
"I liked the property centrally located and the staff are very friendly."
United States
Gracia
The price is ฿2,898
฿3,188 total
includes taxes & fees
31 Aug - 1 Sept
The Executive Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.
Casco View Apartments
3.5 star property
9.0
Wonderful
105 reviews
View
A restaurant with a long counter, chairs, and tables. There are plants and lights decorating the space.
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Hotel Caracas - Casco Viejo
3.0 star property
7.6
Good
4 reviews
View
A hotel room with a large bed, a window with curtains, a city view, and a lamp.
Hotel República
2.0 star property
6.8
196 reviews
View
A hotel entrance with a green facade and a metal fence.
ART CASCO The Hotel
2.0 star property
6.2
12 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Culture: Santa Ana offers a rich tapestry of history and culture, highlighted by the Santa Ana Church and local museums.
  • Free Walking Tours: Explore the area through engaging walking tours that showcase its vibrant streets and historical significance.
  • Family-Friendly Activities: The neighbourhood is perfect for families, with numerous parks and leisure options nearby.
  • Diverse Accommodations: Enjoy a variety of lodging options, from hotels to charming vacation rentals, catering to all preferences.
  • Relaxing Atmosphere: Santa Ana boasts a welcoming vibe, ideal for unwinding while exploring the local dining scene.

Find great hotels near Santa Ana

Discover a range of delightful accommodations in Santa Ana, Panama City, offering both hotel and apartment options. Whether you seek a pet-friendly retreat, a business-friendly environment, or a charming vacation rental, Santa Ana caters to diverse traveller needs. Explore popular choices such as Hotel El Panama and various Panama City hotels, ensuring a memorable stay in this vibrant area of Panamá Province.

  • Central Hotel Panama Casco Viejo: A charming 4-star hotel, Central Hotel Panama Casco Viejo boasts a guest rating of 9.2 out of 10. Located 805m from Santa Ana, this hotel exudes a romantic and spa-themed atmosphere, making it ideal for couples seeking a serene getaway. Guests can indulge in romance packages, featuring amenities like 24-hour room service and Champagne Service. For relaxation, the hotel offers a full spa experience, including outdoor pools and a steam room, perfect for unwinding after a day of exploration. The central location adds to its appeal, allowing easy access to the vibrant city life.
  • American Trade Hotel: Rated 4.5 stars with a guest rating of 9.4 out of 10, American Trade Hotel is situated 644m from Santa Ana. This accommodation is tailored for families and adventure seekers alike, offering recreational activities such as hiking, biking, and nearby scooter rentals. The hotel also provides child-friendly amenities, ensuring a comfortable stay for families. Guests can enjoy romantic dining with garden views and benefit from spa services and outdoor pools, making it a versatile choice for both family fun and intimate escapes.
  • Sofitel Legend Casco Viejo, Panama City: This luxurious 5-star hotel, with an impressive guest rating of 9.8 out of 10, is located 1km from Santa Ana. Sofitel Legend Casco Viejo is designed for those seeking a premium spa experience or business travel. Guests can immerse themselves in relaxation with an array of spa services, including hot stone massages and outdoor treatment rooms, alongside a stunning outdoor pool. The elegant setting and refined service create an atmosphere of sophistication, making it a distinguished choice for discerning travellers.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panama City, offers an inviting blend of family-friendly activities and a lively atmosphere. Visitors can immerse themselves in the welcoming Panamanian vibe, exploring nearby districts that boast relaxing parks and luxurious dining options. With its mix of business and leisure, Santa Ana is the perfect base to discover the best of Panamá Province, ensuring a delightful experience for all types of travellers.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis that offers a unique blend of modernity and tradition. Situated in the heart of the country, it serves as a gateway to various attractions, including shopping centres and scenic parks. With a steady influx of visitors throughout the year, Panama City is particularly lively in January, July, and September. Tourists flock here for family-friendly activities, business events, and urban exploration. Be sure to visit the iconic coastline and local beaches that provide a refreshing escape from the city's hustle.
  • Casco Viejo: Located a mere 644m from Santa Ana, Casco Viejo is a historic neighbourhood that showcases the rich cultural heritage of Panama. This area attracts visitors year-round, peaking in January and during the spring months of March to April. Known for its charming streets and colonial architecture, Casco Viejo offers an array of shopping areas and resorts, making it a perfect destination for families and business travellers alike. Wander through the picturesque streets, enjoy local cuisine, and relax at nearby parks while soaking in the vibrant atmosphere.
  • Barrio Chino: Just 322m from Santa Ana, Barrio Chino is a lively neighbourhood that celebrates the cultural fusion of Panama's Chinese community. This area sees a surge in visitors from February to March and December, drawing families and business-minded tourists. The neighbourhood offers various shopping options, including centres and malls, alongside cultural landmarks such as museums and research facilities. Stroll along the bustling streets to experience the unique blend of traditions and flavours that Barrio Chino has to offer.

Things to do near Santa Ana

Shopping

In Santa Ana, visit the Albrook Mall, a large shopping centre with a variety of stores, from fashion to electronics. For a local experience, explore the nearby artisan markets, where you can find unique handcrafted souvenirs and traditional Panamanian gifts.

Recreation

The Santa Ana Wellness Centre offers holistic treatments including yoga classes and massage therapies, set in a tranquil environment. Nearby, the Parque Natural Metropolitano features scenic trails and opportunities for birdwatching, allowing visitors to reconnect with nature and rejuvenate their spirits.

Adventure

Gatun Eco Adventures offers an exhilarating zipline ropes course located 48km from Santa Ana. Experience the thrill of soaring through the treetops amidst lush landscapes, all while enjoying the vibrant outdoor atmosphere that this adventure venue provides.

Nightlife

The nightlife in Santa Ana offers a vibrant blend of local bars and lively music venues. Visit the popular La Tana for a relaxed atmosphere and enjoy cocktails, or check out Casa Góngora for live performances that showcase local talent, creating an engaging evening experience.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Ana

Santa Ana in Panama City is ideal for family, city, and business-themed holidays. Visitors can explore captivating attractions such as the Santa Ana Church and the nearby San Miguel. The area offers a delightful blend of culture, outdoor activities, and beautiful scenery, making it perfect for those seeking a rich historical experience. Don't miss the local cathedral and history museum for a deeper understanding of Santa Ana's heritage.

  • Interoceanic Canal Museum: Located a mere 805m from Santa Ana, this museum offers a fascinating insight into the history and significance of the Panama Canal. With engaging exhibits, visitors can explore the cultural impact of this engineering marvel on global trade.
  • Metropolitan Cathedral of Panama: Also situated 805m away, this stunning cathedral showcases impressive architecture and rich history. Its serene atmosphere invites contemplation, while its intricate details reflect the cultural heritage of Panama.
  • Independence Square: Just 805m from Santa Ana, this vibrant piazza is a hub of activity, surrounded by historic buildings. It's an ideal spot to experience local culture, with many events and gatherings taking place throughout the year.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Flying into Santa Ana, Panama, is convenient with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is located 3km away, with luxurious hotels such as Hilton Panama and Sofitel Legend Casco Viejo, both offering various transportation services. Balboa (BLB-Panama Pacifico Intl.) is situated 6km away, with The Westin Playa Bonita Panama as a notable hotel option. Finally, Panama City (PTY-Tocumen Intl.) is 21km away, featuring The Santa Maria, A Luxury Collection Hotel, which also provides transport services. Each airport offers easy access to the surrounding hotels, ensuring a smooth journey for visitors.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 131 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.