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8 Dec - 9 Dec
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Top Trending Hotels Near San Francisco, Guayaquil

Rooftop bar, al fresco dining, open daily
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 star property
Simón Bolívar, 8.8 km from San Francisco
9.0 out of 10, Wonderful, (1003)
"Airport shuttle was very convenient "
Canada
Arlene
The price is ฿2,657
฿2,970 total
13 Dec - 14 Dec
Wyndham Garden Guayaquil
Outdoor pool
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 star property
10.6 km from San Francisco
9.4 out of 10, Exceptional, (1007)
"Great stay"
United States
Susan
The price is ฿2,680
฿3,028 total
22 Dec - 23 Dec
Holiday Inn Guayaquil Airport by IHG
2 restaurants, breakfast, lunch, dinner served; Regional cuisine
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

5.0 star property
Simón Bolívar, 9 km from San Francisco
9.0 out of 10, Wonderful, (605)
"Very friendly front desk thank you for a comfortable and enjoyable stay. "
United States
Andrew
The price is ฿3,443
฿3,867 total
19 Dec - 20 Dec
Sheraton Guayaquil Hotel
Exterior
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 star property
Simón Bolívar, 9.1 km from San Francisco
9.0 out of 10, Wonderful, (1002)
"💯"
United States
Sreenidhi
The price is ฿3,327
฿3,739 total
14 Dec - 15 Dec
TRYP by Wyndham Guayaquil Airport
Outdoor pool, pool loungers
Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

5.0 star property
Kennedy, 6.7 km from San Francisco
9.2 out of 10, Wonderful, (631)
"Good service "
United States
Genny
The price is ฿3,052
฿3,436 total
15 Dec - 16 Dec
Radisson Hotel Guayaquil
Lobby
Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

3.5 star property
Kennedy, 7.7 km from San Francisco
9.0 out of 10, Wonderful, (1004)
"Great stay and they were able to accommodate our last minute booking. We had an amazing view of the city and the room was spotless."
United States
Cesar
The price is ฿2,298
฿2,575 total
2 Jan - 3 Jan 2026
Courtyard by Marriott Guayaquil
Lobby
DC Suites Aeropuerto

DC Suites Aeropuerto

3.0 star property
Simón Bolívar, 9.6 km from San Francisco
9.0 out of 10, Wonderful, (578)
"Great location and clean hotel"
United States
Elvin
DC Suites Aeropuerto
Outdoor pool, open 8:00 AM to 9:00 PM, pool loungers
Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel

4.0 star property
Rocafuerte, 6.4 km from San Francisco
9.2 out of 10, Wonderful, (985)
"Great place to Stay.!"
United States
Erwin
The price is ฿2,872
฿3,207 total
14 Dec - 15 Dec
Grand Hotel Guayaquil, an Ascend Collection Hotel
Exterior
Hotel GH Galeria

Hotel GH Galeria

3.5 star property
Downtown Guayaquil, 6.2 km from San Francisco
8.4 out of 10, Very good, (392)
"Location "
United States
Marcelo
Hotel GH Galeria
Reception
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4.0 star property
Rocafuerte, 6.6 km from San Francisco
9.2 out of 10, Wonderful, (1002)
"Nice place to stay"
United States
Victor
The price is ฿2,183
฿2,481 total
6 Jan - 7 Jan 2026
Unipark by Oro Verde Hotels
Children’s activities
Oro Verde Guayaquil

Oro Verde Guayaquil

5.0 star property
Downtown Guayaquil, 6.2 km from San Francisco
9.4 out of 10, Exceptional, (1007)
"Very good stay , recommend 100%"
United States
Lenin
The price is ฿2,840
฿3,204 total
15 Dec - 16 Dec
Oro Verde Guayaquil
Presidential Suite, 1 King Bed, Jetted Tub, River View | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 star property
Puerto Santa Ana, 8.2 km from San Francisco
9.2 out of 10, Wonderful, (1001)
"The hotel and service were great!"
United States
Rolando
The price is ฿3,759
฿4,215 total
19 Dec - 20 Dec
Wyndham Guayaquil Puerto Santa Ana
Outdoor pool, pool loungers
Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield

3.5 star property
Downtown Guayaquil, 7 km from San Francisco
8.6 out of 10, Excellent, (132)
"Excellent location and close to the airport."
United States
Martin Gerardo
Hotel Patrimonial by Greenfield
Exterior
Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast

3.5 star property
6.6 km from San Francisco
9.2 out of 10, Wonderful, (46)
"Excelente Todo "
Costa Rica
Cesar
The price is ฿1,867
฿2,085 total
9 Dec - 10 Dec
Iguanazu Bed & Breakfast
Restaurant
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4.0 star property
Downtown Guayaquil, 7.1 km from San Francisco
9.4 out of 10, Exceptional, (272)
"Great location and great hotel "
United States
José
The price is ฿1,915
฿2,154 total
12 Dec - 13 Dec
Ibis Styles El Malecon Guayaquil
Lobby
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 star property
Kennedy, 8.4 km from San Francisco
8.6 out of 10, Excellent, (811)
"Great room"
United States
Trevor
The price is ฿3,009
฿3,390 total
20 Dec - 21 Dec
Hilton Colon Guayaquil
Garden
Dreamkapture Hostel

Dreamkapture Hostel

2.0 star property
Alborada, 10.4 km from San Francisco
8.8 out of 10, Excellent, (19)
"Good Pool !"
Australia
Julie
Dreamkapture Hostel
In-room safe, blackout curtains, soundproofing, iron/ironing board
Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil

3.5 star property
Rocafuerte, 7 km from San Francisco
9.0 out of 10, Wonderful, (70)
"We stayed here twice and both the times to staff was excellent, the property was centrally located, it felt safe, and welcoming. I highly recommend this hotel and felt like it exceeded our expectations."
United States
Ravi
The price is ฿2,226
฿3,140 total
2 Jan - 3 Jan 2026
Doubletree By Hilton Guayaquil
Lobby
Hotel Palace Guayaquil

Hotel Palace Guayaquil

4.0 star property
Rocafuerte, 6.7 km from San Francisco
9.2 out of 10, Wonderful, (911)
"Good place to stay "
United States
GIOVANNY
The price is ฿1,964
฿2,209 total
22 Dec - 23 Dec
Hotel Palace Guayaquil
Massages
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4.0 star property
Garzota, 10.1 km from San Francisco
8.6 out of 10, Excellent, (220)
"Loved my stay. It was very clean and close to the airport. "
United States
Yesenia
Hotel Puerto Pacifico Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Botanical Garden while you're familiarising yourself with the larger area.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Top San Francisco Hotel Reviews

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil

10/10 Excellent
"Everything worked perfectly. The air conditioner kept the temp all night. The bathroom was large and clean. All staff was friendly. We enjoyed our food and drinks on the rooftop when we arrived. "
Heather 1-night trip
Posted 2 months ago
Doubletree By Hilton Guayaquil
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

10/10 Excellent
"I didn't eat breakfast. Overall my stay was excellent. Had staff meet me at airport and take me to the hotel. Check-in was very quick. Found the room to be spacious, very clean, and the bathroom was well stocked with the shower necessities. Was very pleased with my stay and highly recommend the hotel."
Joe 1-night trip
Posted 2 months ago
Hotel Puerto Pacifico Guayaquil Airport

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Frequently asked questions

What is San Francisco like?
Travellers will be sure to enjoy their time in Guayaquil's San Francisco neighbourhood.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in San Francisco.
What is there to do around this Guayaquil neighbourhood?
A few places to visit in the area around San Francisco include U.S. Consulate General, Mall del Sur and Estero de Mongon. While you're out sightseeing in Guayaquil, make sure that you visit other sights such as Banco Pichincha Monumental Stadium or Civic Center.