A coastal cityscape with a sunset, high-rise buildings, and a marina.

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Our top choices for San Antonio hotels

1. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,014 reviews)
"The room was clean daily and the staff are friendly and courteous."
United States
Paula
The price is ฿3,352
฿3,687 total
includes taxes & fees
9 Oct - 10 Oct
Courtyard by Marriott Panama Metromall

2. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
4.5 km from San Antonio
8.6 out of 10, Excellent, (1,814 reviews)
"Short stay and it was good...staff at check in was very helpful."
United States
Tanese
The price is ฿3,586
฿3,944 total
includes taxes & fees
24 Sept - 25 Sept
Riande Aeropuerto Hotel & Casino

3. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
6.1 km from San Antonio
8.6 out of 10, Excellent, (2,731 reviews)
"Great hotel Loved the inclusive breakfast. Loved the Location"
United States
Xenia
The price is ฿4,471
฿5,137 total
includes taxes & fees
1 Oct - 2 Oct
Crowne Plaza Panama Airport by IHG

4. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
4 km from San Antonio
9.6 out of 10, Exceptional, (754 reviews)
"Great hotel overall"
United States
PAULA
The price is ฿8,904
฿9,794 total
includes taxes & fees
15 Oct - 16 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
5.7 km from San Antonio
9.0 out of 10, Wonderful, (203 reviews)
"great airport shuttle and very attentive staff, room was great"
United States
Paul
The price is ฿3,387
฿4,397 total
includes taxes & fees
21 Oct - 22 Oct
ORHO Hotel Boutique 15 Minutes from PTY Airport

6. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
10.9 km from San Antonio
9.6 out of 10, Exceptional, (1,354 reviews)
"excellent breakfast great location"
United States
Maria
The price is ฿3,255
฿3,580 total
includes taxes & fees
4 Oct - 5 Oct
Ramada Plaza by Wyndham Panama Punta Pacifica

7. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
6.2 km from San Antonio
9.2 out of 10, Wonderful, (383 reviews)
"Nice place good location"
United States
Rame
The price is ฿3,468
฿5,579 total
includes taxes & fees
29 Sept - 30 Sept
Corporate Stays Arcadia | Executive Furnished Apartments

8. The Westin Panama

The Westin Panama
4.0 star property
6.8 km from San Antonio
9.0 out of 10, Wonderful, (349 reviews)
"Hotel was ok"
United Kingdom
Luke
The price is ฿6,808
฿7,489 total
includes taxes & fees
10 Oct - 11 Oct
The Westin Panama

9. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
12.4 km from San Antonio
9.0 out of 10, Wonderful, (5,985 reviews)
"Beautiful hotel, breakfast was wonderful, location was very convenient."
United States
Sandrelly
The price is ฿4,559
฿5,015 total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama

10. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
12.7 km from San Antonio
9.4 out of 10, Exceptional, (2,233 reviews)
"Great hotel, great location"
Canada
Catherine
The price is ฿3,941
฿4,335 total
includes taxes & fees
24 Sept - 25 Sept
Plaza Paitilla Inn Hotel

11. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
10.4 km from San Antonio
8.8 out of 10, Excellent, (1,006 reviews)
"It was a great stay"
United States
Shaniyah
The price is ฿4,382
฿4,820 total
includes taxes & fees
2 Oct - 3 Oct
Aloft by Marriott Panama

12. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
10.4 km from San Antonio
8.6 out of 10, Excellent, (1,001 reviews)
"Great facility and great location."
United States
Noel
The price is ฿5,813
฿6,394 total
includes taxes & fees
1 Oct - 2 Oct
Sheraton Grand Panama

13. JW Marriott Panama

JW Marriott Panama
5.0 star property
12 km from San Antonio
9.2 out of 10, Wonderful, (1,007 reviews)
"Great experience in great hotel You can’t be wrong if you book room with them, I will be back again for sure"
United States
Nemanja
The price is ฿8,717
฿9,589 total
includes taxes & fees
10 Oct - 11 Oct
JW Marriott Panama

14. MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
18.8 km from San Antonio
8.0 out of 10, Very good, (277 reviews)
"Good hotel for families"
United States
Martha
The price is ฿2,198
฿2,418 total
includes taxes & fees
25 Sept - 26 Sept
MARINN Tropical Vibes Hotel

15. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
12.5 km from San Antonio
8.6 out of 10, Excellent, (1,720 reviews)
"Location is wonderful."
United States
Jorge Luis
The price is ฿3,662
฿4,028 total
includes taxes & fees
10 Oct - 11 Oct
Decapolis Hotel Panama City

16. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
12.2 km from San Antonio
9.0 out of 10, Wonderful, (2,072 reviews)
"Good area around for short time visit"
United States
Eliel
The price is ฿1,958
฿2,154 total
includes taxes & fees
24 Sept - 25 Sept
Principe Hotel and Suites

17. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
12.3 km from San Antonio
9.0 out of 10, Wonderful, (791 reviews)
"It was a great stay"
United States
Shontel
The price is ฿3,312
฿3,643 total
includes taxes & fees
4 Oct - 5 Oct
Best Western El Dorado Panama Hotel

18. Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
11.5 km from San Antonio
9.0 out of 10, Wonderful, (228 reviews)
"It was good for a night before heading to the airport."
United States
Mark
The price is ฿969
฿1,066 total
includes taxes & fees
27 Sept - 28 Sept
Panama House Bed & Breakfast

19. The Executive Hotel

The Executive Hotel
3.5 star property
12.8 km from San Antonio
9.2 out of 10, Wonderful, (1,266 reviews)
"great location, great hotel"
United States
Sandra
The price is ฿3,079
฿3,387 total
includes taxes & fees
6 Oct - 7 Oct
The Executive Hotel

20. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
12.5 km from San Antonio
8.6 out of 10, Excellent, (1,749 reviews)
"It was a beautiful stay ..enjoyed every moment"
United States
Devika
The price is ฿5,320
฿5,852 total
includes taxes & fees
24 Sept - 25 Sept
Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Rufina Alfaro

While you're in Rufina Alfaro, take in top sights like Metromall Panama and jump on the metro at San Antonio Station to see more of the city.

Belisario Porras

Even though there aren't top sights in Belisario Porras, you can explore the larger area and take in top sights like Estadio Rommel Fernandez. Jump on the metro at Los Andes Station to see more of the city.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

Omar Torrijos

While you're in Omar Torrijos, take in top sights like Templo Bahá'í and jump on the metro at San Isidro Station to see more of the city.

Top San Antonio Hotel Reviews

Frequently asked questions

What's it like in San Antonio?
San Antonio is a neighbourhood that travellers like for its shopping and gardens.
Where is the best hotel for a stay in San Antonio?
Based on our traveller data, Courtyard by Marriott Panama Metromall is one of the top choices for your stay in San Antonio. This hotel offers a restaurant and an outdoor pool.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in San Antonio.
What is there to do in this San Miguelito neighbourhood?
Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.