Search Hotels Near Saint Francis Medical Center, Cape Girardeau

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Mar - 9 Mar
Tomorrow
9 Mar - 10 Mar
Next weekend
13 Mar - 15 Mar
In two weeks
20 Mar - 22 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Saint Francis Medical Center hotels

Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
0.8 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1,016 reviews)
"Great place "
United States
Kelly
The price is ฿3,187
฿3,595 total
includes taxes & fees
15 Mar - 16 Mar
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
0.5 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (795 reviews)
"Excellent stay"
United States
Christina
The price is ฿3,372
฿3,804 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn Cape Girardeau I 55 East
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
0.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1,006 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ฿3,028
฿3,416 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
0.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1,007 reviews)
"Awesome stay!"
United States
Breckin
The price is ฿2,868
฿3,236 total
includes taxes & fees
15 Mar - 16 Mar
Drury Inn & Suites Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
1.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (162 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
The price is ฿3,224
฿3,637 total
includes taxes & fees
19 Mar - 20 Mar
Fairfield Inn & Suites by Marriott Cape Girardeau
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
0.9 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (1,007 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ฿2,295
฿2,589 total
includes taxes & fees
15 Mar - 16 Mar
Pear Tree Inn Cape Girardeau West
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
1.6 km from Saint Francis Medical Center
8.2 out of 10, Very good, (901 reviews)
"Room was clean and spacious."
United States
George
The price is ฿2,550
฿3,052 total
includes taxes & fees
15 Mar - 16 Mar
Candlewood Suites Cape Girardeau by IHG
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
2 km from Saint Francis Medical Center
6.0 out of 10, (212 reviews)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ฿2,008
฿2,346 total
includes taxes & fees
7 Apr - 8 Apr
Town House Inn Cape Giradreau
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
3.6 km from Saint Francis Medical Center
10.0 out of 10, Exceptional, (20 reviews)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is ฿4,790
฿5,403 total
includes taxes & fees
15 Mar - 16 Mar
Rockwood Inn
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
4.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (493 reviews)
"Very nice hotel!"
United States
Angie
The price is ฿3,984
฿4,515 total
includes taxes & fees
19 Mar - 20 Mar
Courtyard by Marriott Cape Girardeau Downtown
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
5.7 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (114 reviews)
"It was a nice stay"
United States
Douglas
The price is ฿3,110
฿3,540 total
includes taxes & fees
15 Mar - 16 Mar
Tru By Hilton Cape Girardeau
Lobby sitting area

The Riverview

The Riverview
4.0 star property
4.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (523 reviews)
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is ฿3,069
฿3,462 total
includes taxes & fees
15 Mar - 16 Mar
The Riverview
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
6.7 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (719 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is ฿2,682
฿2,903 total
includes taxes & fees
15 Mar - 16 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
15.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1,009 reviews)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is ฿2,550
฿2,695 total
includes taxes & fees
15 Mar - 16 Mar
Drury Inn & Suites Jackson MO
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
6.7 km from Saint Francis Medical Center
8.2 out of 10, Very good, (748 reviews)
"Clean and comfortable every time. This is a “go to” hotel "
United States
Jacqulyn
The price is ฿2,937
฿3,179 total
includes taxes & fees
9 Mar - 10 Mar
Comfort Suites Jackson-Cape Girardeau
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
3.8 km from Saint Francis Medical Center
7.2 out of 10, Good, (706 reviews)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is ฿2,123
฿2,395 total
includes taxes & fees
16 Mar - 17 Mar
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Saint Francis Medical Center Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Great experience. We will pick Drury every time we travel. "
ken 1-night trip
Posted 8 hours ago
Drury Inn & Suites Cape Girardeau

Hotels near other Saint Francis Medical Center attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park

Riverfront Bridge Park

4.4/5 (74 reviews)
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Saint Francis Medical Center?
Saint Francis Medical Center is located in Cape Girardeau. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Saint Francis Medical Center?
Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Saint Francis Medical Center. Other good choices within a short distance include Drury Inn & Suites Cape Girardeau and Pear Tree Inn Cape Girardeau West.
How many hotels are there close to Saint Francis Medical Center?
Expedia has 9 hotels and other accommodation options within a mile from Saint Francis Medical Center.
If I need to cancel the hotel reservation for my stay near Saint Francis Medical Center, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best options available near Saint Francis Medical Center.
What can I see and do near Saint Francis Medical Center?
You might spend a leisurely day outdoors at Cape Rock Park and Fort D Historic Site. Create some family memories at Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.