Skip to main content

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Travelers can enjoy the indoor pool and spa treatments after exploring the area, then wake up to a delicious breakfast that makes mornings easy

Choose dates to view prices

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers comfort in a rural setting with free breakfast and an indoor pool. Relax at the onsite spa and sun loungers by the pool. Dry cleaning, laundry services, and luggage storage are available, with highly praised staff.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free Wi-Fi
  • Air-conditioning
The current price is ฿3,392
฿3,827 total
includes taxes & fees
26 Apr - 27 Apr

Room options

Available filters for rooms
Showing 9 of 9 rooms

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(35 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(61 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(15 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room, 1 Queen Bed

9.4 out of 10
Exceptional
(6 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
Mod logo
Sign in to view eligible discounts and perks. More rewards for more adventures!
Sign inSign up, it's free

About the area

Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Visit our Cape Girardeau travel guide
Map
3253 William Street, Cape Girardeau, MO, 63701

What's nearby

  • View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park
    Riverfront Bridge Park
    6 min drive - 7.0 km
  • Panorama of Academic Hall, Southeast Missouri State University
    Southeast Missouri State University
    6 min drive - 6.3 km
  • Saint Francis Medical Center
    6 min walk - 0.6 km
  • Century Casino & Hotel Cape Girardeau
    8 min drive - 9.4 km
  • Show Me Center
    9 min drive - 9.1 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    10 min drive

Restaurants

  • Chick-fil-A
    7 min walk
  • Rhodes
    20 min walk
  • McDonald's
    10 min walk
  • White Castle
    10 min walk
  • Qdoba Mexican Eats
    13 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel near Shawnee National Forest
You can look forward to free breakfast, dry cleaning/laundry services and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the on-site spa. In addition to a business centre, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
  • Swimming pool, along with sunloungers
  • Free self-parking
  • An indoor pool, a banquet hall and laundry services
  • Luggage storage, smoke-free property and 1 meeting room
  • Guest reviews give top marks for the breakfast and helpful staff
Room features
All 102 rooms include comforts, such as premium bedding and pillow menus, in addition to thoughtful touches, such as laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the cleanliness rooms at the property.
Other amenities include:
  • Pillowtop mattresses and down duvets
  • Bathrooms with free toiletries and hairdryers
  • 52-inch flat-screen TVs with premium channels
  • Separate sitting areas, mini fridges and microwaves

Similar properties

Desk, laptop workspace, blackout curtains, free cots/infant beds
Pear Tree Inn Cape Girardeau West
Cape Girardeau
  • Breakfast included
  • Pet-friendly
  • Parking included
  • Free Wi-Fi
9.0 out of 10, Wonderful, 999 reviews
The price is ฿2,326
฿2,624 total
includes taxes & fees
6 May - 7 May
Pear Tree Inn Cape Girardeau West
Compare similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business centre
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cots (infant beds) are not available

Payment types at the property

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM to 11 PM.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of 8 Apr 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on 26 Apr 2026 start from ฿3,392, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?

No, pets are not allowed at this property.

How much is parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Self-parking is free at this property.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; check-in end time: anytime.

What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Checkout is at 11 AM.

Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?

Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 miles (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

Have a question?

AI iconBeta

Get instant answers with AI powered search of property information and reviews.

Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

9.6

Cleanliness

9.4

Location

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 778 out of 1000 reviews
Rating 8 - Good. 149 out of 1000 reviews
Rating 6 - Okay. 40 out of 1000 reviews
Rating 4 - Poor. 15 out of 1000 reviews
Rating 2 - Terrible. 18 out of 1000 reviews

Reviews

Verified

10/10 Excellent

Amber

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Vanessa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was recommended by a friend of ours. The hotel staff were great. It was clean and quiet. Me and my husband enjoyed our stay.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Arriel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room staff is very nice parking it great
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I was amazed to find out this place is 20+ years old. It is in great shape. Room was wonderful. Breakfast was great; very lovely stay.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Rex

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Summer

Liked: Cleanliness, staff & service, amenities
It was amazing check in to check out
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Nellie

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff was very friendly.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Dawn

Liked: Cleanliness, amenities, property conditions & facilities
Everyone kind & place very clean.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great staff and clean rooms.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice room. There was a little noise from other rooms or perhaps from the hallways. The breakfast was very good.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Connie

Liked: Cleanliness, staff & service, amenities
Spacious room, clean, & comfy with everything we needed.
Stayed 1 night in Nov 2025
Verified

8/10 Good

Bridgett

Liked: Cleanliness, amenities, property conditions & facilities
Very clean rooms, no unwanted unlocks of doors while you are in your room. The guest serves were delightful and very happy to help. Breakfast was nice and consistently restocked. Only reason for four and half stars, the very first attendant was a little rude. I only saw her the night of check in. Also the pancake maker wouldn’t work, I do craved pancakes and couldn’t get any. But other than that it was a great stay!!!
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Emily

Liked: Cleanliness, property conditions & facilities
Clean and easy check in
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Erik

Liked: Cleanliness, staff & service, amenities
The room was clean, the staff were friendly, and they gave out free cookies in the evening, not just breakfast in the morning.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Marianne

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very nice with comfy bed. It’s a lovely area. We went to a brewery in town and had pizza, salad and a beer.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Kelly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was right off the interstate with lots of restaurant options
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Carey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very Friendly check in Parking lot was very Safe A lot of know restaurants within walking distance from Hotel,Very Clean.
Stayed 2 nights in Aug 2025
Verified

10/10 Excellent

Christine

We had an excellent comfortable stay here! Loved our room and full breakfast.
Stayed 2 nights in Jun 2025
Verified

8/10 Good

Carrie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great room and good breakfast. Great place to stay with central location.
Stayed 1 night in May 2025
Verified

10/10 Excellent

Gretchen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Amie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great customer service!! The people next to our room were very loud with children yelling amd running around all night.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Crystal

Liked: Cleanliness, staff & service, property conditions & facilities
Pool is nice! Place is perfect
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Cherish

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We got greeted with such a friendly smile and attitude as soon as we got in. The room was clean and roomy. Would highly recommend and come back.
Stayed 1 night in Sep 2025
Verified

6/10 Okay

Scott

Liked: Cleanliness, staff & service, amenities
The room was nice and clean but located near an ice machine that clunked all night long. I would suggest asking about the location of your room and the ice machine. Nice place but less than ideal stay
Stayed 1 night in Nov 2025