
Find hotels in Cape Girardeau, MO from ฿2,226
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Cape Girardeau
Pet friendly
Apartment
Family friendly
Waterpark
Condo
Check prices for these dates
Tonight
16 Sep - 17 SepTomorrow
17 Sep - 18 SepThis weekend
18 Sep - 20 SepNext weekend
25 Sep - 27 SepOur top choices for Cape Girardeau hotels




1. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Sandra
฿3,321
฿3,746 total
includes taxes & fees
20 Sept - 21 Sept




2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
ELAINE
฿3,354
฿3,818 total
includes taxes & fees
20 Sept - 21 Sept




3. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
Teresa
฿2,989
฿3,372 total
includes taxes & fees
20 Sept - 21 Sept




4. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
Kristin
฿4,155
฿4,708 total
includes taxes & fees
27 Sept - 28 Sept




5. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
Raidas
฿2,391
฿2,697 total
includes taxes & fees
20 Sept - 21 Sept




6. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
Rebekah
฿3,513
฿3,963 total
includes taxes & fees
27 Sept - 28 Sept




7. The Riverview
The RiverviewCape Girardeau
Alyssa
฿3,796
฿4,282 total
includes taxes & fees
20 Sept - 21 Sept




8. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
Carlos
฿3,359
฿3,790 total
includes taxes & fees
27 Sept - 28 Sept




9. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
Stephen
฿1,973
฿2,226 total
includes taxes & fees
27 Sept - 28 Sept




10. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
Darlene
฿2,968
฿3,378 total
includes taxes & fees
22 Sept - 23 Sept




11. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
Samuel
฿2,823
฿3,367 total
includes taxes & fees
11 Oct - 12 Oct




12. Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
Joshua
฿2,491
฿2,910 total
includes taxes & fees
24 Sept - 25 Sept




13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Elaine
฿2,795
฿3,025 total
includes taxes & fees
22 Sept - 23 Sept




14. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
William
฿2,756
฿2,914 total
includes taxes & fees
21 Sept - 22 Sept




15. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
VICTORIA
฿2,518
฿2,725 total
includes taxes & fees
11 Oct - 12 Oct




16. Town House Inn
Town House InnJackson
Taylor
฿2,367
฿2,562 total
includes taxes & fees
27 Sept - 28 Sept




17. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
JANEEN
฿3,359
฿3,656 total
includes taxes & fees
17 Sept - 18 Sept




18. Makanda Inn
Makanda InnMakanda
Michele
฿8,699
฿9,917 total
includes taxes & fees
17 Sept - 18 Sept
Stay near popular Cape Girardeau attractions

Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

Riverfront Bridge Park
8.8/10 (129 reviews)
Enjoy panoramic views of the Mississippi River and Bill Emerson Memorial Bridge from this peaceful riverside park. Stroll along the well-maintained walking paths and find perfect spots for memorable photographs.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
Hunter Valley Winery
7.4/10 (48 reviews)
Sip award-winning Chambourcin and Chardonnay at this picturesque Missouri estate with lake views. Bring a picnic basket and enjoy live weekend music on the deck overlooking the sculpture garden.
Show Me Center
8.6/10 (40 reviews)
The Show Me Centre hosts Southeast Missouri State basketball and major concerts in a versatile arena setting. Catch Redhawks games or enjoy performances by renowned artists in this regional entertainment hub.
Riverfront Park
8.0/10 (2 reviews)
This riverside haven features terraced seating overlooking the Mississippi and a flood wall adorned with historical murals. Stroll the riverfront trail while watching paddle boats dock at this picturesque park.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
This 3.5-acre water park thrills with a 265-foot free-fall slide and 700-foot lazy river. Families can splash in the pirate ship playground or relax in shaded lounge areas during summer months.
Cape Rock Park
8.6/10 (36 reviews)
Perched on a limestone bluff, Cape Rock Park offers panoramic views of the Mississippi River and passing barges. Bring binoculars to spot wildlife at this historic former trading post.
Learn more about Cape Girardeau
Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.
See all hotels in Cape Girardeau
Top Cape Girardeau Hotel Reviews
Drury Inn & Suites Jackson MO
10/10 Excellent
"What a great stay! It’s the best buffet breakfast in the area."
EC Reed's Mercantile and Hotel
10/10 Excellent
"This hotel is perfect!!! We loved the check in process which is the easiest i have ever encountered. The hotel is so cute and nostalgic. I fell in love with the room, the lobby and the restaurant. Very nice people here. The food was absolutely delicious. The music playing in the hotel lobby was lite and relaxing. The bed in room 6 was so comfortable like a big fluffy cloud. The mercantile has the most unique items. I wish i would have time to visit the old time soda shop. The coffee bar was awesome. I love the patriot coffee k cups . The honey for the coffee was top tier. There is nothing about this place that we did not love. Please do yourself a favor and stop by, i promise its worth the stop. There is also a small barber shop at the entrance of the hotel. Thank yall for the kindness shown to us and we cant wait to visit again"
Tru By Hilton Cape Girardeau
10/10 Excellent
"Excellent hotel!! Great water pressure in showers!"
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Great experience- food, cleanliness, friendly staff"
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Excellent breakfast,friendly staff and clean rooms"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"The receptionist was very courteous. Helped answer all my questions. We loved the room. And we had a great breakfast before we left."
Town House Inn Cape Giradreau
8/10 Good
"The outside needed cleaning, but the room was very clean and well maintained."
Hotel 7 Inn Anna
10/10 Excellent
"Staff were very accommodating and made the stay very pleasant."
More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
฿1,973
฿2,226 total
27 Sept - 28 Sept
includes taxes & fees

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
฿2,391
฿2,697 total
20 Sept - 21 Sept
includes taxes & fees

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
฿2,823
฿3,367 total
11 Oct - 12 Oct
includes taxes & fees
8/10 Very good! (1,000 reviews)

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
฿2,968
฿3,378 total
22 Sept - 23 Sept
includes taxes & fees
9.6/10 Exceptional! (179 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
฿3,354
฿3,818 total
20 Sept - 21 Sept
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd Cape Girardeau MO
฿3,513
฿3,963 total
27 Sept - 28 Sept
includes taxes & fees
