Santa Clara Travel Guide

Panama City


Popular places to visit

Things to do


Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is ฿4,821 per night from 12 Apr to 13 Apr
฿4,821
฿5,303 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,073 reviews)
The only thing preventing a 5-star review is that towels were removed from my room, and also from a friend’s room in a totally different floor. We arrived tired from the day and couldn’t take a shower for almost an hour and after 5 calls to the front desk. Other than that l, everything was great. ...

Reviewed on 12 Mar 2026

Hotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is ฿4,045 per night from 3 Apr to 4 Apr
฿4,045
฿4,450 total
3 Apr - 4 Apr
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
Clean and comfortable room. Bathroom needs an overall. Faucets are hard to open and close.

Reviewed on 7 Mar 2026

Sheraton Grand Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is ฿4,280 per night from 23 Mar to 24 Mar
฿4,280
฿4,708 total
23 Mar - 24 Mar
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,498 reviews)
Clean and quiet, perfect for a short trip. 100% recommended.

Reviewed on 11 Mar 2026

Crowne Plaza Panama Airport by IHG
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is ฿3,413 per night from 23 Mar to 24 Mar
฿3,413
฿3,755 total
23 Mar - 24 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,018 reviews)
The pool and pool side rooms are very much recommended

Reviewed on 11 Mar 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
The price is ฿6,362 per night from 31 Mar to 1 Apr
฿6,362
฿6,999 total
31 Mar - 1 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (1,002 reviews)
Enjoyed our stay, staff were very friendly and helpful!

Reviewed on 10 Mar 2026

W Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
The price is ฿2,845 per night from 17 Mar to 18 Mar
฿2,845
฿3,824 total
17 Mar - 18 Mar
includes taxes & fees
Stay at this spa B&B in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Via Espana and Avenida Balboa are located ...
8.8/10 Excellent! (772 reviews)
There's a lot to like about this hotel. I found it to be much more attractive than it is in the photographs. I was assigned a room on the 10th floor and I liked the room from the moment I walked in. Everything worked fine.... The Wi-Fi, the TV, etc. The hot water pressure was good and the flow was ...

Reviewed on 11 Mar 2026

Waymore Hotel Spa & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Clara

modern skyline of downtown Panama City   - skyscraper building  aerial -

Juan Diaz

You'll enjoy the restaurants and shopping in Juan Diaz. You might want to make time for a stop at Los Pueblos Commercial Center or Estadio Rommel Fernandez.

Juan Diaz
Panorámica de Cuidad de panamá, con vista a Corredor Sur y Costa del Este, día soleado

Costa del Este

Travellers like the restaurants in Costa del Este, and Atrio Mall is a top attraction you might want to visit.

Costa del Este
Fascination for obelisks

Parque Lefevre

You'll enjoy the restaurants and museums in Parque Lefevre. You might want to make time for a stop at Panama Viejo or National Craft Market.

Parque Lefevre
The Bridge of the Americas in summer, Panama City

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Francisco
Almost no space between modern cruiseship or cruise ship liner and concrete walls of Panama Canal inside locks

Bethania

Bethania might not have many top sights, but El Dorado Mall and Panama Canal Murals are two attractions nearby that you can check out.

Bethania
Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio


Santa Clara Travel Guide