Name: Ramada Plaza by Wyndham Panama Punta Pacifica
Price range: ฿3,445

Things to do

Panama City: All-Inclusive Catamaran Cruise to Taboga Island

฿3,305

per adult

94% of travellers recommend

From Panama City: San Blas Island Hopping Day Tour

฿4,841

per adult

98% of travellers recommend

Monkey and Sloth Jungle Habitat Panama Tour

฿2,003

per adult

96% of travellers recommend

Panama City: Poin Glass Observation Deck Ticket with VR Tour

฿1,072

per adult

100% of travellers recommend

Transfer to Panama Canal (Miraflores Locks)

฿467

per adult

100% of travellers recommend

Panama City: Poin Full Package Experience

฿5,175

per adult

98% of travellers recommend

See all activities in Panama City

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

฿4,457

฿4,903 total

1 Dec - 2 Dec

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...

9/10 Wonderful! (6,167 reviews)

"Breakfast"

Reviewed on 2 Nov 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

฿3,952

฿4,347 total

30 Nov - 1 Dec

includes taxes & fees

Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...

7.8/10 Good! (1,007 reviews)

"Clean room."

Reviewed on 2 Nov 2026

Megapolis Hotel Panamá

Avenida Balboa Panama City

฿5,655

฿6,221 total

9 Nov - 10 Nov

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...

8.6/10 Excellent! (1,832 reviews)

"The bed sheets were soiled in the room. Fixtures in the shower, lamps and toilet were falling a part. The staff was friendly and the breakfast was amazing. It's situated in an ideal location to get around with Uber and taxi services. The restaurant inside the hotel was nice and food came out in a ..."

Reviewed on 2 Nov 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

฿4,729

฿5,425 total

11 Nov - 12 Nov

includes taxes & fees

Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

฿8,867

฿8,867 total

1 Dec - 2 Dec

includes taxes & fees

Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. Popular attractions Albrook Shopping Mall ...

7.8/10 Good! (1,120 reviews)

"Excelente servicios! Volveremos pronto, muy contentos de no tener que preocuparnos por nada! El hotel te ofrece todo lo que se necesita para un gran descanso."

Reviewed on 2 Nov 2026

Ramada Plaza by Wyndham Panama Punta Pacifica

Via Israel y Calle 71, San Francisco Panama City Panama

฿3,445

฿3,790 total

9 Nov - 10 Nov

includes taxes & fees

Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...

See all 1,808 properties in Santa Clara

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most. Learn more about Santa Clara

A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.