Search Hotels in Mission Bay, San Francisco

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission Bay hotels

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Mission Bay
9.6 out of 10, Exceptional, (2,424 reviews)
"Wonderful stay, staff, location and options ! "
United States
Alexandria
The price is ฿6,532
฿7,688 total
includes taxes & fees
31 Jan - 1 Feb
LUMA Hotel San Francisco

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.0 out of 10, Wonderful, (7,298 reviews)
"Nice location, GREAT breakfast, friendly staff, comfortable room"
United States
Gary
The price is ฿3,381
฿5,275 total
includes taxes & fees
10 Feb - 11 Feb
Hotel Riu Plaza Fisherman's Wharf

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 3 km from Mission Bay
8.8 out of 10, Excellent, (2,307 reviews)
"We loved our stay! "
United States
Christine
The price is ฿3,050
฿3,589 total
includes taxes & fees
15 Feb - 16 Feb
Hilton San Francisco Financial District

YOTEL San Francisco

YOTEL San Francisco
3.0 star property
2.1 km from Mission Bay
8.2 out of 10, Very good, (1,010 reviews)
"Great place to stay in the city. Rooms are small but modern and clean staff is courteous and friendly. There is 24 hour security its a great place and is affordable."
United States
Sherretha
The price is ฿2,056
฿3,708 total
includes taxes & fees
21 Jan - 22 Jan
YOTEL San Francisco

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission Bay
9.0 out of 10, Wonderful, (5,149 reviews)
"Great stay!"
United States
Carlos Emiro
The price is ฿3,958
฿4,659 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Golden Gateway by IHG

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.6 km from Mission Bay
9.0 out of 10, Wonderful, (3,823 reviews)
"Nice place to stay"
United States
Harold Franklin
The price is ฿3,801
฿5,982 total
includes taxes & fees
19 Feb - 20 Feb
Hotel Caza Fisherman's Wharf

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 2.8 km from Mission Bay
9.0 out of 10, Wonderful, (2,909 reviews)
"nice location"
United Kingdom
Natthaya
The price is ฿3,795
฿4,467 total
includes taxes & fees
23 Jan - 24 Jan
Club Quarters Hotel in San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
8.6 out of 10, Excellent, (2,380 reviews)
"Great place to stay with kids. Walkable to most everything and seemed very safe "
United States
Amy
The price is ฿3,912
฿5,891 total
includes taxes & fees
28 Jan - 29 Jan
Hotel Zephyr San Francisco

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.4 km from Mission Bay
9.2 out of 10, Wonderful, (1,672 reviews)
"The hotel was very nice and located near many attractions. "
United States
Sergio
The price is ฿3,427
฿5,360 total
includes taxes & fees
9 Feb - 10 Feb
Hotel Zoe Fisherman's Wharf

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
2.5 km from Mission Bay
9.4 out of 10, Exceptional, (3,165 reviews)
"Fantastic....kindest hotel and such a comfortable stay!"
United States
Amy
The price is ฿2,785
฿3,287 total
includes taxes & fees
25 Jan - 26 Jan
Chancellor Hotel on Union Square

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 2.3 km from Mission Bay
9.4 out of 10, Exceptional, (2,691 reviews)
"Very well kept hotel , staff keep it good vibes and fun all around the area to be had!"
United States
Robert
The price is ฿5,286
฿7,659 total
includes taxes & fees
16 Feb - 17 Feb
Hotel Nikko San Francisco

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square, 2.4 km from Mission Bay
8.8 out of 10, Excellent, (2,829 reviews)
"Great location, room was clean and staff was helpful."
United States
Laura
The price is ฿17,791
฿20,939 total
includes taxes & fees
5 Feb - 6 Feb
Handlery Union Square Hotel

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.0 out of 10, Wonderful, (2,279 reviews)
"Clean room, courteous staff, break fast and great location."
United States
Claudia
The price is ฿4,063
฿5,798 total
includes taxes & fees
15 Feb - 16 Feb
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Sonesta Emeryville - San Francisco Bay Bridge

Sonesta Emeryville - San Francisco Bay Bridge
3.0 star property
11.2 km from Mission Bay
8.6 out of 10, Excellent, (1,321 reviews)
"Convenient location, friendly staff"
United States
Diane
The price is ฿3,719
฿4,523 total
includes taxes & fees
25 Jan - 26 Jan
Sonesta Emeryville - San Francisco Bay Bridge

Comfort Inn by the Bay

Comfort Inn by the Bay
2.5 star property
Cow Hollow, 4.5 km from Mission Bay
8.4 out of 10, Very good, (1,276 reviews)
"Clean, comfortable beds, good breakfast, friendly staff, good location. "
United States
Charles
The price is ฿3,235
฿3,807 total
includes taxes & fees
29 Jan - 30 Jan
Comfort Inn by the Bay

King George Hotel

King George Hotel
3.0 star property
Union Square, 2.4 km from Mission Bay
8.6 out of 10, Excellent, (2,094 reviews)
"The staff were all friendly and courteous, the room and bathroom were very clean, the beds were comfortable and a very good location."
United States
Jamie
The price is ฿2,785
฿3,746 total
includes taxes & fees
23 Jan - 24 Jan
King George Hotel

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
19.6 km from Mission Bay
8.6 out of 10, Excellent, (2,311 reviews)
"Great price and great stay. Friendly staff "
United States
Abu
The Marina Inn on San Francisco Bay

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown
3.0 star property
0.9 km from Mission Bay
9.4 out of 10, Exceptional, (1,950 reviews)
"Great overall stay, friendly staff"
United States
Brian
The price is ฿4,657
฿5,481 total
includes taxes & fees
23 Jan - 24 Jan
Hyatt Place San Francisco Downtown

San Remo Hotel

San Remo Hotel
2.0 star property
North Beach, 4.2 km from Mission Bay
8.8 out of 10, Excellent, (1,001 reviews)
"I was there to enjoy my vacation and the facility and location did not disappoint me. "
Canada
Hsiao-Feng
San Remo Hotel

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
22 km from Mission Bay
9.0 out of 10, Wonderful, (1,280 reviews)
"Good place to stay, clean and good breakfast."
United States
Xiaohong
The price is ฿2,953
฿3,394 total
includes taxes & fees
25 Jan - 26 Jan
Best Western Inn & Suites San Mateo - San Francisco Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Mission Bay Hotel Reviews

Frequently asked questions

What is Mission Bay like?
Travellers will be sure to enjoy their time in San Francisco's Mission Bay neighbourhood. Make sure that you visit Chase Center and Lefty O'Doul Bridge as part of your Mission Bay travel plans.
Where is the best place to stay in Mission Bay?
Based on Expedia customer reviews, LUMA Hotel San Francisco is the highest ranked property in Mission Bay. This hotel is a short 5-minute walk from Oracle Park, and it offers a restaurant and a fitness centre.
How many hotels will I be able to find in Mission Bay?
When you want to put your feet up after a day of exploring the sights in San Francisco, you can choose from 18 Expedia hotels and other accommodation options in Mission Bay.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mission Bay.
What are the top things to see and do in Mission Bay?
Chase Center, Lefty O'Doul Bridge and Lucky Strike San Francisco are just a few attractions to check out in Mission Bay. While you're out sightseeing, Oracle Park and Pier 39 are a couple of additional sights to visit in San Francisco.
How can I get around Mission Bay and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at UCSF/Chase Center Stop, Mission Rock Station or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.