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Our top choices for Mesice holiday rentals

Aparthotel in Mala Strana

Royal Prague City Apartments
4.0 star property
8.8 out of 10, Excellent, (954)
"I liked the location and have no complaints about the accommodations. "
United States
Alex
The price is ฿1,372
฿1,689 total
includes taxes & fees
11 Jan - 12 Jan 2026
Royal Prague City Apartments

Aparthotel in Prague City Center

Mottl House by Adrez
4.0 star property
9.4 out of 10, Exceptional, (271)
"Beautiful rooms, especially the bathroom! Excellent location right in the city centre next to the Wenceslas Square. Lovely building very clean. Would definitely stay there again. "
United Kingdom
Christopher
Mottl House by Adrez

Aparthotel in Prague City Center

MOOo by the Castle
4.0 star property
10.0 out of 10, Exceptional, (249)
"Wonderful rooms close to everything! Will definitely stay here next time"
United States
Christopher
MOOo by the Castle

Aparthotel in Prague City Center

Old Town Square Apartments
3.5 star property
7.8 out of 10, Good, (335)
"Very roomy and comfortable "
United Kingdom
Jane
The price is ฿1,622
฿2,885 total
includes taxes & fees
11 Jan - 12 Jan 2026
Old Town Square Apartments

Aparthotel in Prague City Center

Numa Prague Republika
5.0 star property
9.0 out of 10, Wonderful, (97)
"Highly recommended, especially for families. Breakfast is highly recommended, reasonably priced and very delicious."
United States
Christian
The price is ฿2,561
฿3,019 total
includes taxes & fees
13 Jan - 14 Jan 2026
Numa Prague Republika

Aparthotel in Nové Město

NOBILIS RESIDENCE
3.0 star property
9.8 out of 10, Exceptional, (79)
"Outstanding accommodations! Clean, comfortable and refined. "
United States
Aaron
The price is ฿2,151
฿2,558 total
includes taxes & fees
11 Jan - 12 Jan 2026
NOBILIS RESIDENCE

Apartment in Prague 5

KORA APARTMENTS
3.0 star property
9.4 out of 10, Exceptional, (149)
"Absolutely lovely stay. With a lot of space. "
United States
Anna
The price is ฿1,685
฿2,186 total
includes taxes & fees
7 Jan - 8 Jan 2026
KORA APARTMENTS

Aparthotel in Nové Město

City Pop 2Night Prague - Self check-in
4.0 star property
9.0 out of 10, Wonderful, (339)
"Great location. Spotlessly clean and good amenities "
United Kingdom
philip
The price is ฿2,044
฿2,440 total
includes taxes & fees
13 Jan - 14 Jan 2026
City Pop 2Night Prague - Self check-in

Apartment in Prague City Center

Golden Angel Suites by Adrez Living
3.5 star property
9.2 out of 10, Wonderful, (457)
"Great location, spacious, clean and highly recommend!"
Canada
Ellery
The price is ฿1,809
฿2,173 total
includes taxes & fees
13 Jan - 14 Jan 2026
Golden Angel Suites by Adrez Living

Apartment in Prague City Center

MOOo Downtown
4.0 star property
9.8 out of 10, Exceptional, (479)
"Fun apartment hotel, spacious and in an old building located in excellent location for seeing Prague. Many good restaurants and shopping close by. Staff are friendly and hotel is kept up and clean."
United States
Elizabeth
MOOo Downtown

Apartment in Smichov

Honest SMICHOV
3.5 star property
9.2 out of 10, Wonderful, (73)
"Easy check in and out "
Australia
Jasper
The price is ฿1,692
฿1,895 total
includes taxes & fees
11 Jan - 12 Jan 2026
Honest SMICHOV

Aparthotel in Prague City Center

White Swan Boutique Apartments
3.0 star property
9.2 out of 10, Wonderful, (24)
"Great stay, perfect condition and location"
United Kingdom
Hannah
The price is ฿1,643
฿1,988 total
includes taxes & fees
14 Jan - 15 Jan 2026
White Swan Boutique Apartments

Aparthotel in Prague City Center

City Nest Apartments by Adrez Living
3.5 star property
9.0 out of 10, Wonderful, (282)
"I really enjoyed my stay.Cute place!"
Canada
Gabriella
The price is ฿1,511
฿1,840 total
includes taxes & fees
12 Jan - 13 Jan 2026
City Nest Apartments by Adrez Living

Aparthotel in Prague 2

Prague Urban Apartments 48
2.0 star property
9.8 out of 10, Exceptional, (19)
"we‘ve been to Prag for a 3 day trip, and the Apartment gave us everything we needed … it was in perfect condition, brand new, had a lot of space and was very light full … the owner were very kind and helpful by planing our trip and by giving us travel tips and you can feel that everything comes from heart … "
Germany
Alexandra
The price is ฿2,057
฿2,455 total
includes taxes & fees
23 Dec - 24 Dec
Prague Urban Apartments 48

Aparthotel in Nové Město

Numa Prague Flow
3.5 star property
9.4 out of 10, Exceptional, (225)
"Clean, easy to get in and out of, safe & fantastic location"
United Kingdom
Gemma
The price is ฿2,392
฿2,830 total
includes taxes & fees
20 Jan - 21 Jan 2026
Numa Prague Flow

Apartment in Prague City Center

Prague Kampa APTs by Michal&Friends
3.5 star property
9.4 out of 10, Exceptional, (25)
"Great location, walkable to restaurants and Prague's attractions. Clean, all the amenities. "
Canada
Diane
Prague Kampa APTs by Michal&Friends

Aparthotel in Nové Město

CHILL Apartments
3.5 star property
9.2 out of 10, Wonderful, (205)
"Great location"
Canada
Romina
CHILL Apartments
4.0 star property
9.4 out of 10, Exceptional, (41)
"Excellent stay !!!"
United States
Mariela
The price is ฿1,521
฿2,954 total
includes taxes & fees
11 Jan - 12 Jan 2026
Rašínovo nábřeží - Riverside Residence

Apartment in Prague City Center

3 Epoques Apartments by Adrez Living
4.0 star property
9.2 out of 10, Wonderful, (271)
"Very clean and spacious apartment close to tourist attractions."
United States
Payam
The price is ฿2,135
฿2,544 total
includes taxes & fees
20 Jan - 21 Jan 2026
3 Epoques Apartments by Adrez Living

Aparthotel in Prague City Center

The Botanist by Adrez
4.0 star property
9.6 out of 10, Exceptional, (102)
"Loved the location and room was amazing "
United Kingdom
Harriet
The price is ฿2,148
฿2,553 total
includes taxes & fees
20 Jan - 21 Jan 2026
The Botanist by Adrez
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesice Hotel Reviews

Find out more about Mesice

Search for holiday rentals in Mesice on Expedia! You can easily find your home rentals, villas, holiday apartments in Mesice using one of the methods below:

  • View our selection of featured holiday rentals in Mesice
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  • Enter your travel dates to view the best deals on holiday rentals in Mesice while they last

Look no further and take a look at our great range of rental properties in Mesice!

Frequently asked questions

Can I find a holiday rental in Mesice?

Yes, there are holiday rentals close to the most popular sights in Mesice, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Mesice has to offer?

Apartment Colours Prague Center: This holiday home rental outside of Mesice is in the historical district, and equipped with air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop.

What can I see and do in Mesice?

Explore the area and family-friendly sights such as Sea World, or get out into nature at a spot like Prague Botanical Gardens. O2 Arena and Sportovní hala Fortuna are a couple of places you'll find in the wider area.

What are holiday rentals like in Mesice?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Mesice. Holiday rentals feature amenities such as hot tubs, fire pits and patios so your stay will be comfortable. If you're concerned about cleanliness, a holiday rental can offer a sense of privacy away from shared hotel lifts and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a holiday rental than in a traditional hotel, which makes a holiday rental a popular choice for small groups.