Barrio de Santiago Travel Guide

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
Study a collection of 19th-century images of jungle-covered ancient ruins, which provided historians with a wealth of knowledge about the Mayans.
See properties

Things to do

Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

฿330
per adult
80% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
Mérida: La Quinta Montes Molina Museum Entrance

Mérida: La Quinta Montes Molina Museum Entrance

฿283
per adult
Mérida: La Quinta Montes Molina Museum Entrance
Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

฿2,638
per adult
94% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
Live Like Local in Real Merida

Live Like Local in Real Merida

฿167
per adult
Live Like Local in Real Merida
Chichen Pueblos Magicos, Izamal + Valladolid Day Trip

Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included

฿3,973
per adult
92% of travellers recommend
Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included
Cenote Yuum Kimil

4 Cenotes Tour in Homún all inclusive from Merida

฿2,708
per adult
94% of travellers recommend
4 Cenotes Tour in Homún all inclusive from Merida
See all activities in Mérida

Top hotels in Barrio de Santiago

Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
The price is ฿1,190 per night from 11 Oct to 12 Oct
฿1,190
฿1,434 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
8.6/10 Excellent! (436 reviews)
"Everything was great during my entire stay"

Reviewed on 14 Aug 2026

Hotel Casa 57
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
The price is ฿2,729 per night from 8 Nov to 9 Nov
฿2,729
฿3,288 total
8 Nov - 9 Nov
includes taxes & fees
Stay at this spa hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (464 reviews)
"Loved the small private pool and the room was very clean."

Reviewed on 5 Oct 2026

Hotel Unknown
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
The price is ฿1,088 per night from 11 Oct to 12 Oct
฿1,088
฿1,311 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular attractions ...
Hotel Ambassador Merida
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
The price is ฿1,289 per night from 12 Oct to 13 Oct
฿1,289
฿1,553 total
12 Oct - 13 Oct
includes taxes & fees
Stay at this boutique hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
Casa Aura Hotel, Mérida
Casona 61 Boutique Hotel

Casona 61 Boutique Hotel

3.5 out of 5
Calle 61 entre 66 y 68 Mérida YUC
The price is ฿1,407 per night from 21 Oct to 22 Oct
฿1,407
฿1,695 total
21 Oct - 22 Oct
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.8/10 Excellent! (422 reviews)
"Staff were incredible and the breakfast was huge and tasted amazing"

Reviewed on 7 Oct 2026

Casona 61 Boutique Hotel
Hotel Boutique La Casona By Kavia

Hotel Boutique La Casona By Kavia

3.5 out of 5
532 Calle 59 Centro Mérida YUC
The price is ฿1,496 per night from 11 Oct to 12 Oct
฿1,496
฿1,803 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular attractions ...
Hotel Boutique La Casona By Kavia
See all 1,392 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas for the activities you enjoy most.
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is known for its abundant dining options, and you can plan a trip to Plaza Grande and Paseo 60 while you're in town.

A sunset over a body of water with a rocky shoreline.
Photo by Tony Lozano
Open Photo by Tony Lozano

Chelem

If you're spending some time in Chelem, Chelem Park is a top sight worth visiting.

A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travellers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

A meal with tacos, a salad, and a drink at a restaurant.
Photo by Alba and John
Open Photo by Alba and John

Santa Lucia

If you're looking for some top things to see and do in Santa Lucia and surrounding area, you can visit Plaza Grande and Paseo 60.

Barrio de Santiago Travel Guide