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Check availability on Medical Center District Gay-Friendly Hotels

Our top choices for Medical Center District LGBT-friendly hotels

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San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1000)
"The room is clean and the hotel staff are all nice including the staff from the restourant"
United States
Frank Charles
The price is ฿2,826
฿3,358 total
includes taxes & fees
12 Dec - 13 Dec
San Antonio Marriott Northwest Medical Center
Food and drink
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3108)
"quite place with good breakfast"
United States
Juan
The price is ฿2,819
฿3,332 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Bar (on property)
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1001)
"Room was clean, staff was very friendly!!"
United States
Ray
The price is ฿2,826
฿3,340 total
includes taxes & fees
19 Dec - 20 Dec
Courtyard by Marriott Medical Center San Antonio
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1287)
"Great place to stay and visit "
United States
Harry
The price is ฿2,857
฿3,377 total
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites San Antonio Northwest Medical Center
Property entrance
OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (225)
"Always great stay"
United States
Juan
The price is ฿1,715
฿2,224 total
includes taxes & fees
25 Dec - 26 Dec
OYO Inn & Suites Medical Center San Antonio
Lobby
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1000)
"good staff. good stay"
United States
Divya
The price is ฿3,207
฿3,791 total
includes taxes & fees
12 Dec - 13 Dec
SpringHill Suites by Marriott San Antonio Medical Center/NW
Terrace/patio
Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1920)
"Great stay overall "
United States
Melissa
The price is ฿4,831
฿6,830 total
includes taxes & fees
17 Dec - 18 Dec
Hyatt Regency San Antonio Riverwalk
Exterior
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
3.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (4100)
"Very nice stay."
United States
Anthony
The price is ฿3,810
฿4,503 total
includes taxes & fees
16 Dec - 17 Dec
Drury Plaza Hotel San Antonio Riverwalk
Bar (on property)
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3.0 star property
Downtown San Antonio
7.8 out of 10, Good, (3753)
"Definitely stay again "
United States
Jesse
The price is ฿2,257
฿3,224 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Free daily buffet breakfast
Tru by Hilton San Antonio North

Tru by Hilton San Antonio North

Tru by Hilton San Antonio North
2.5 star property
San Antonio
8.8 out of 10, Excellent, (621)
"Staff here was nice and communicative. "
United States
Mark
The price is ฿2,261
฿2,639 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton San Antonio North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How do I find a gay-friendly hotel in Medical Center District?
If you're searching for a place where you'll feel at ease in Medical Center District, our website has the gay-friendly hotel you're looking for. Discover the people, places and traditions found only in Medical Center District.
What's the best LGBTQ-friendly hotel in Medical Center District?
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. San Antonio Marriott Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio are other good choices for your holiday.
How many LGBTQ-friendly hotels are there in Medical Center District?
There are currently 7 gay-friendly accommodation options in Medical Center District.
What should I see while I'm in Medical Center District?
During your trip, get out and enjoy everything Medical Center District has to offer. You and your travelling companions may want to visit USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16. While you're here, capture some great memories of your trip with stops at Lackland Air Force Base and Six Flags Fiesta Texas.
What is an LGBTQ-friendly hotel in Medical Center District?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Medical Center District, these hotels operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from an LGBTQ-friendly Medical Center District hotel?
Stay at a gay-friendly hotel in Medical Center District and you won't have to hide or your sexuality or your gender identity when you check in. Many of our LGBTQ-friendly accommodation options offer wedding ceremonies and honeymoon packages for same-sex couples.