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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,075 reviews)
"Great staff, clean room and affordable rates "
United States
Geoffrey
The price is ฿4,404
฿5,019 total
includes taxes & fees
24 Jan - 25 Jan
Sonesta Select Scottsdale at Mayo Clinic Campus

HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town
3.0 star property
Downtown Scottsdale, 15.5 km from Mayo Clinic
8.8 out of 10, Excellent, (1,152 reviews)
"Great stay, clean rooms and in the heart of town."
United States
Edmond
The price is ฿7,192
฿8,197 total
includes taxes & fees
1 Feb - 2 Feb
HYATT house Scottsdale/Old Town

Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
3.5 star property
12.4 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,009 reviews)
"Very nice room, great breakfast and close to a shopping center with restaurants. "
United States
SHANNON
The price is ฿6,889
฿8,927 total
includes taxes & fees
25 Jan - 26 Jan
Sonesta Suites Scottsdale Gainey Ranch

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
10.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (920 reviews)
"Awesome resort hotel for kids"
Canada
Vanessa
The price is ฿5,630
฿6,589 total
includes taxes & fees
21 Jan - 22 Jan
Great Wolf Lodge Arizona

Hilton Garden Inn Scottsdale Old Town

Hilton Garden Inn Scottsdale Old Town
3.0 star property
Brown and Stetson Business, 15.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,002 reviews)
"The front desk staff was great and I enjoyed the continental breakfast. A very reasonably priced hotel in a good location."
United States
Marie
The price is ฿5,391
฿6,144 total
includes taxes & fees
25 Jan - 26 Jan
Hilton Garden Inn Scottsdale Old Town

Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square
2.0 star property
Fashion Square, 16 km from Mayo Clinic
7.8 out of 10, Good, (1,074 reviews)
"Cool area..near shops and food.."
United States
Sean
The price is ฿2,831
฿3,226 total
includes taxes & fees
25 Jan - 26 Jan
Motel 6 Old town Scottsdale/Fashion Square

Scottsdale Parkview Resort

Scottsdale Parkview Resort
3.5 star property
17.6 km from Mayo Clinic
8.0 out of 10, Very good, (5,151 reviews)
"Great stay, friendly staff and excellent location!"
United States
Michael Jason
The price is ฿2,834
฿3,456 total
includes taxes & fees
21 Jan - 22 Jan
Scottsdale Parkview Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,846 reviews)
"Fantastic room, staff and breakfast!"
United States
Terry G
The price is ฿4,512
฿5,143 total
includes taxes & fees
28 Jan - 29 Jan
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Great hotel "
United States
Laura
The price is ฿4,532
฿5,165 total
includes taxes & fees
26 Jan - 27 Jan
Aiden by Best Western Scottsdale North

Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG
3.0 star property
9.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (979 reviews)
"Clean room , breakfast delicious, courteous staff. "
United States
David
The price is ฿7,832
฿8,930 total
includes taxes & fees
29 Jan - 30 Jan
Staybridge Suites Scottsdale - Talking Stick by IHG

Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town
3.0 star property
Brown and Stetson Business, 15.6 km from Mayo Clinic
8.6 out of 10, Excellent, (1,384 reviews)
"Great Stay! "
Canada
Bahareh
The price is ฿4,624
฿5,270 total
includes taxes & fees
25 Jan - 26 Jan
Hyatt Place Scottsdale/Old Town

Hyatt House North Scottsdale

Hyatt House North Scottsdale
3.5 star property
14.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (894 reviews)
"The hotel was very nice and convenient. Breakfasts were good- nice selection. "
United States
Bruce
The price is ฿7,486
฿8,532 total
includes taxes & fees
30 Jan - 31 Jan
Hyatt House North Scottsdale

Hilton Vacation Club Scottsdale Villa Mirage

Hilton Vacation Club Scottsdale Villa Mirage
3.5 star property
13.1 km from Mayo Clinic
8.6 out of 10, Excellent, (1,002 reviews)
"Nice location, nice activities, and restaurant."
United States
Bob
The price is ฿4,519
฿6,082 total
includes taxes & fees
25 Jan - 26 Jan
Hilton Vacation Club Scottsdale Villa Mirage

Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort
3.5 star property
11.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,002 reviews)
"Plenty of parking and room to roam. Enjoyed the visit"
United States
Kenneth
The price is ฿5,326
฿7,003 total
includes taxes & fees
25 Jan - 26 Jan
Hilton Vacation Club Scottsdale Links Resort

Sleep Inn North Scottsdale near Mayo Clinic

Sleep Inn North Scottsdale near Mayo Clinic
2.5 star property
Paradise Valley Village, 13.6 km from Mayo Clinic
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean, check in was quick and easy, and breakfast was served early, just as promised."
United States
Jeffrey
The price is ฿5,517
฿6,238 total
includes taxes & fees
28 Jan - 29 Jan
Sleep Inn North Scottsdale near Mayo Clinic

Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.7 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,783 reviews)
"Very polite staff, great breakfast, clean room! "
United States
Kathryn
The price is ฿4,839
฿5,518 total
includes taxes & fees
1 Feb - 2 Feb
Comfort Suites Scottsdale Talking Stick Entertainment District

Home2 Suites by Hilton Scottsdale Old Town

Home2 Suites by Hilton Scottsdale Old Town
2.5 star property
Downtown Scottsdale, 16.7 km from Mayo Clinic
8.8 out of 10, Excellent, (1,008 reviews)
"Clean rooms, spacious, cleaned daily, plenty of towels, staff was very kind and beds were comfortable! Definitely stay here again."
United States
Misty
The price is ฿6,526
฿7,437 total
includes taxes & fees
25 Jan - 26 Jan
Home2 Suites by Hilton Scottsdale Old Town

Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
3.0 star property
18.5 km from Mayo Clinic
8.6 out of 10, Excellent, (301 reviews)
"Room was clean and service was great."
United States
Zoar
The price is ฿3,396
฿3,870 total
includes taxes & fees
25 Jan - 26 Jan
Papago Scottsdale by Reside, Trademark Collection by Wyndham

Revival Scottsdale Studios

Revival Scottsdale Studios
2.5 star property
Paradise Valley Village, 12.8 km from Mayo Clinic
7.4 out of 10, Good, (1,130 reviews)
"Nice rooms"
United States
Benito
The price is ฿3,749
฿4,239 total
includes taxes & fees
25 Jan - 26 Jan
Revival Scottsdale Studios

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,205 reviews)
"Great place to stay! "
United States
Stephanie
The price is ฿8,935
฿10,183 total
includes taxes & fees
25 Jan - 26 Jan
Hotel Valley Ho
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Western Spirit: Scottsdale's Museum of the West to Scottsdale Fashion Square – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club are top sights worth seeing.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and Arizona Boardwalk while you're sightseeing around the area.