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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.4 out of 10, Very good, (1,085 reviews)
"Awesome place to stay. "
United States
Tyler
The price is ฿2,445
฿2,787 total
includes taxes & fees
31 May - 1 Jun
Sonesta Select Scottsdale at Mayo Clinic Campus

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
4.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,485 reviews)
"Great place, clean, great breakfast!"
United States
Kristin
The price is ฿3,361
฿3,800 total
includes taxes & fees
5 Jun - 6 Jun
Drury Inn & Suites Phoenix Airport

Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
23.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,097 reviews)
"As always, great place. "
United States
Jeffrey
The price is ฿3,135
฿3,576 total
includes taxes & fees
6 Jun - 7 Jun
Hyatt Place Tempe Phoenix Airport

Fairfield Inn & Suites by Marriott Tempe

Fairfield Inn & Suites by Marriott Tempe
3.0 star property
20.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (391 reviews)
"Friendly and helpful front desk team made it short stay a pleasure. "
United States
stuart
The price is ฿2,687
฿3,065 total
includes taxes & fees
17 May - 18 May
Fairfield Inn & Suites by Marriott Tempe

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
2.5 star property
27.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,838 reviews)
"Great place to stay!"
United States
Beth
The price is ฿3,232
฿3,655 total
includes taxes & fees
24 May - 25 May
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,638 reviews)
"Great stay, very clean and staff was great"
Canada
Daniel Di
The price is ฿4,334
฿5,864 total
includes taxes & fees
7 Jun - 8 Jun
Talking Stick Resort

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,000 reviews)
"Really beautiful property and nice rooms. "
United States
Taylor
The price is ฿3,597
฿6,005 total
includes taxes & fees
18 May - 19 May
Wekopa Casino Resort

SureStay By Best Western Phoenix Airport

SureStay By Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (2,099 reviews)
"nice hotel, rooms were clean"
United States
Francisco
The price is ฿2,747
฿3,106 total
includes taxes & fees
15 May - 16 May
SureStay By Best Western Phoenix Airport

Hilton Garden Inn Phoenix Airport

Hilton Garden Inn Phoenix Airport
3.0 star property
27.6 km from Mayo Clinic
8.8 out of 10, Excellent, (1,009 reviews)
"Comfortable, easy access to airport"
United States
Inna
The price is ฿2,889
฿3,267 total
includes taxes & fees
7 Jun - 8 Jun
Hilton Garden Inn Phoenix Airport

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean room, helpful staff, nice pool and hot tub area"
United States
Donna Michelle
The price is ฿3,247
฿3,707 total
includes taxes & fees
14 Jun - 15 Jun
Inn at Eagle Mountain

Hilton Phoenix Airport

Hilton Phoenix Airport
4.0 star property
25 km from Mayo Clinic
8.8 out of 10, Excellent, (1,091 reviews)
"Was a great place and close to airport "
United States
Kelly
The price is ฿2,885
฿3,262 total
includes taxes & fees
13 Jun - 14 Jun
Hilton Phoenix Airport

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,432 reviews)
"Nice atmosphere and service was great"
United States
Gaye
The price is ฿5,207
฿5,935 total
includes taxes & fees
1 Jun - 2 Jun
Hotel Valley Ho

Home2 Suites by Hilton Phoenix Downtown

Home2 Suites by Hilton Phoenix Downtown
3.0 star property
30.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,353 reviews)
"Room was nice and quiet, breakfast could have more options staff was nice and warm. "
United States
Elvira
The price is ฿3,729
฿4,216 total
includes taxes & fees
28 May - 29 May
Home2 Suites by Hilton Phoenix Downtown

Element Scottsdale at SkySong

Element Scottsdale at SkySong
3.0 star property
18.5 km from Mayo Clinic
9.4 out of 10, Exceptional, (836 reviews)
"Good breakfast "
United States
John
The price is ฿2,812
฿3,205 total
includes taxes & fees
30 May - 31 May
Element Scottsdale at SkySong

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG
2.5 star property
20.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,036 reviews)
"Very clean hotel one of the best breakfast and friendly staff .."
Canada
Ronak
The price is ฿2,844
฿3,216 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,850 reviews)
"Breakfast was great every day I was there."
United States
Ian
The price is ฿3,265
฿3,730 total
includes taxes & fees
28 May - 29 May
Hyatt Place Phoenix/Mesa

SpringHill Suites Phoenix Airport/Tempe

SpringHill Suites Phoenix Airport/Tempe
3.0 star property
23.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,019 reviews)
"location"
United States
Robert
The price is ฿2,445
฿2,789 total
includes taxes & fees
31 May - 1 Jun
SpringHill Suites Phoenix Airport/Tempe

The Westin Tempe

The Westin Tempe
4.0 star property
22.7 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,020 reviews)
"Great place to stay. It was close to everything we wanted to do. "
United States
Isaac
The price is ฿3,200
฿4,781 total
includes taxes & fees
13 Jun - 14 Jun
The Westin Tempe

Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.8 out of 10, Excellent, (2,769 reviews)
"Staff was so friendly and helpful. Bar/restaurant was great and tacos were so delicious."
United States
Chris
The price is ฿2,889
฿3,267 total
includes taxes & fees
7 Jun - 8 Jun
Hilton Garden Inn Phoenix Airport North

My Place Hotel-Phoenix East Mesa AZ

My Place Hotel-Phoenix East Mesa AZ
2.0 star property
28.2 km from Mayo Clinic
8.8 out of 10, Excellent, (193 reviews)
"Nice place to stay"
United States
Roy
The price is ฿3,694
฿4,222 total
includes taxes & fees
25 May - 26 May
My Place Hotel-Phoenix East Mesa AZ
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Cactus Park are top sights worth seeing.

East Mesa

While East Mesa isn't home to many top sights, Superstition Springs Center and Augusta Ranch Golf Club are some notable places to visit nearby.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and Arizona Boardwalk while you're sightseeing around the area.