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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,074 reviews)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is ฿4,119
฿4,694 total
includes taxes & fees
20 Jan - 21 Jan
Sonesta Select Scottsdale at Mayo Clinic Campus

Hyatt Place Tempe / Phoenix / University

Hyatt Place Tempe / Phoenix / University
3.0 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,135 reviews)
"Everything was excellent: the service, the hotel’s location, and the breakfast!"
United States
Amaris Dinorah Coya
The price is ฿4,999
฿5,702 total
includes taxes & fees
11 Jan - 12 Jan
Hyatt Place Tempe / Phoenix / University

Arizona Grand Resort & Spa

Arizona Grand Resort & Spa
4.0 star property
28.6 km from Mayo Clinic
8.6 out of 10, Excellent, (2,322 reviews)
"Great stay! "
United States
Tyson
The price is ฿5,628
฿9,207 total
includes taxes & fees
10 Jan - 11 Jan
Arizona Grand Resort & Spa

The Westin Tempe

The Westin Tempe
4.0 star property
22.7 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,003 reviews)
"Great location "
United States
Darrell
The price is ฿3,993
฿5,655 total
includes taxes & fees
11 Jan - 12 Jan
The Westin Tempe

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,183 reviews)
"Great place to stay! "
United States
Stephanie
The price is ฿8,931
฿10,178 total
includes taxes & fees
11 Jan - 12 Jan
Hotel Valley Ho

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,311 reviews)
"Excellent accommodations"
Canada
Ray
The price is ฿7,046
฿8,930 total
includes taxes & fees
11 Jan - 12 Jan
Talking Stick Resort

Omni Tempe Hotel at ASU

Omni Tempe Hotel at ASU
4.0 star property
22.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,370 reviews)
" Location was great, very clean and pool area is fabulous."
United States
Niaomi
The price is ฿5,005
฿6,606 total
includes taxes & fees
11 Jan - 12 Jan
Omni Tempe Hotel at ASU

Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Scottsdale Plaza Resort & Villas (soon to be Kimpton)
4.0 star property
13.5 km from Mayo Clinic
8.8 out of 10, Excellent, (2,172 reviews)
"Nice resort with clean rooms! Food at restaurant was amazing! Will return for a visit! "
Canada
Mahtab
The price is ฿6,356
฿8,551 total
includes taxes & fees
15 Jan - 16 Jan
Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University
2.5 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,001 reviews)
"Room was clean, Staff was awesome."
United States
keith
The price is ฿5,313
฿6,061 total
includes taxes & fees
10 Jan - 11 Jan
Hyatt House Tempe/Phoenix/University

Embassy Suites by Hilton Phoenix Downtown North

Embassy Suites by Hilton Phoenix Downtown North
3.5 star property
28.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,240 reviews)
"Great rooms fantastic staff quality breakfast"
United States
Mike
The price is ฿5,471
฿6,186 total
includes taxes & fees
10 Jan - 11 Jan
Embassy Suites by Hilton Phoenix Downtown North

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,000 reviews)
"It was an amazing stay! "
United States
Whitney
Wekopa Casino Resort

Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town
3.0 star property
Brown and Stetson Business, 15.6 km from Mayo Clinic
8.6 out of 10, Excellent, (1,375 reviews)
"Great Stay! "
Canada
Bahareh
The price is ฿4,370
฿4,981 total
includes taxes & fees
11 Jan - 12 Jan
Hyatt Place Scottsdale/Old Town

Vīb Hotel by Best Western Phoenix - Tempe

Vīb Hotel by Best Western Phoenix - Tempe
3.0 star property
22.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (730 reviews)
"We had a great stay! Great location and really nice rooms "
United States
Itai
The price is ฿4,660
฿5,315 total
includes taxes & fees
13 Jan - 14 Jan
Vīb Hotel by Best Western Phoenix - Tempe

Rise Uptown Hotel

Rise Uptown Hotel
4.0 star property
27.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,125 reviews)
"Great staff, great rooms."
United States
Robert
The price is ฿5,301
฿7,237 total
includes taxes & fees
12 Jan - 13 Jan
Rise Uptown Hotel

Sonesta Select Tempe Downtown

Sonesta Select Tempe Downtown
3.0 star property
22.7 km from Mayo Clinic
8.4 out of 10, Very good, (1,002 reviews)
"Location, staff were very nice"
United States
Emma
The price is ฿4,999
฿5,702 total
includes taxes & fees
11 Jan - 12 Jan
Sonesta Select Tempe Downtown

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
10.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (915 reviews)
"Awesome resort hotel for kids"
Canada
Vanessa
The price is ฿5,065
฿5,927 total
includes taxes & fees
8 Feb - 9 Feb
Great Wolf Lodge Arizona

Holiday Inn Express & Suites Tempe by IHG

Holiday Inn Express & Suites Tempe by IHG
2.5 star property
28 km from Mayo Clinic
8.8 out of 10, Excellent, (1,001 reviews)
"Clean room, quiet stay, breakfast is very good. The staff and front desk ladies are so nice and polite."
United States
Irma
The price is ฿3,867
฿4,411 total
includes taxes & fees
12 Jan - 13 Jan
Holiday Inn Express & Suites Tempe by IHG

The McCormick Scottsdale

The McCormick Scottsdale
3.5 star property
13 km from Mayo Clinic
8.4 out of 10, Very good, (1,293 reviews)
"Clean room, good view, friendly staff. "
United States
Aravinda
The price is ฿3,647
฿5,232 total
includes taxes & fees
11 Jan - 12 Jan
The McCormick Scottsdale

HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town
3.0 star property
Downtown Scottsdale, 15.5 km from Mayo Clinic
8.8 out of 10, Excellent, (1,141 reviews)
"Great stay, clean rooms and in the heart of town."
United States
Edmond
The price is ฿4,999
฿5,697 total
includes taxes & fees
11 Jan - 12 Jan
HYATT house Scottsdale/Old Town

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Great hotel "
United States
Laura
The price is ฿3,883
฿4,425 total
includes taxes & fees
11 Jan - 12 Jan
Aiden by Best Western Scottsdale North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Western Spirit: Scottsdale's Museum of the West to Scottsdale Fashion Square – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.