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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,079 reviews)
"Spotless room, wonderful amenities, a MOST comfortable bed,polite staff. Will definitely stay here again. "
United States
Cathleen
The price is ฿3,928
฿4,476 total
includes taxes & fees
1 Apr - 2 Apr
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
3.0 star property
14.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,003 reviews)
"Quality place"
United States
Michael
The price is ฿5,036
฿5,740 total
includes taxes & fees
1 Apr - 2 Apr
Sonesta ES Suites Scottsdale Paradise Valley

HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town
3.0 star property
Downtown Scottsdale, 15.5 km from Mayo Clinic
8.8 out of 10, Excellent, (1,186 reviews)
"Great stay, clean rooms and in the heart of town."
United States
Edmond
The price is ฿4,561
฿5,198 total
includes taxes & fees
1 Apr - 2 Apr
HYATT house Scottsdale/Old Town

Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
3.5 star property
12.4 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,015 reviews)
"Great stay"
United States
Kiley
The price is ฿5,036
฿6,823 total
includes taxes & fees
29 Mar - 30 Mar
Sonesta Suites Scottsdale Gainey Ranch

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
10.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (976 reviews)
"Great place for family time"
United States
Rachel
The price is ฿6,816
฿7,976 total
includes taxes & fees
7 Apr - 8 Apr
Great Wolf Lodge Arizona

Scottsdale Parkview Resort

Scottsdale Parkview Resort
3.5 star property
17.6 km from Mayo Clinic
8.0 out of 10, Very good, (5,190 reviews)
"Rooms were very nice and staff was very kind. "
United States
Janelle Marie
The price is ฿3,775
฿4,604 total
includes taxes & fees
7 Apr - 8 Apr
Scottsdale Parkview Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,893 reviews)
"Fantastic room, staff and breakfast!"
United States
Terry G
The price is ฿3,280
฿3,738 total
includes taxes & fees
2 Apr - 3 Apr
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,020 reviews)
"I stay hte often and like the ccomodations, breakfast and beds!"
United States
Colleen
The price is ฿3,269
฿3,725 total
includes taxes & fees
5 Apr - 6 Apr
Aiden by Best Western Scottsdale North

Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.7 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,815 reviews)
"Great place to stay. People, facility, rooms, breakfast were great. "
United States
Gary
The price is ฿4,276
฿4,875 total
includes taxes & fees
6 Apr - 7 Apr
Comfort Suites Scottsdale Talking Stick Entertainment District

Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square
2.0 star property
16 km from Mayo Clinic
7.8 out of 10, Good, (1,133 reviews)
"Great location for shopping and dining "
Canada
Jason
The price is ฿2,819
฿3,213 total
includes taxes & fees
5 Apr - 6 Apr
Motel 6 Old town Scottsdale/Fashion Square

Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town
3.0 star property
Brown and Stetson Business, 15.6 km from Mayo Clinic
8.6 out of 10, Excellent, (1,426 reviews)
"Great Stay! "
Canada
Bahareh
The price is ฿5,100
฿5,812 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Scottsdale/Old Town

Best Western Plus Sundial

Best Western Plus Sundial
2.5 star property
Downtown Scottsdale, 15.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,005 reviews)
"Great spot!"
United States
Jovan
The price is ฿5,055
฿5,761 total
includes taxes & fees
5 Apr - 6 Apr
Best Western Plus Sundial

Hyatt House North Scottsdale

Hyatt House North Scottsdale
3.5 star property
14.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (920 reviews)
"Great location and very clean hotel!"
United States
Steve
The price is ฿4,941
฿5,631 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt House North Scottsdale

Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
3.0 star property
18.5 km from Mayo Clinic
8.8 out of 10, Excellent, (398 reviews)
"Clean room and the staff was amazing!"
United States
Brian
The price is ฿4,390
฿5,003 total
includes taxes & fees
6 Apr - 7 Apr
Papago Scottsdale by Reside, Trademark Collection by Wyndham

Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG
3.0 star property
9.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (990 reviews)
"Clean room , breakfast delicious, courteous staff. "
United States
David
The price is ฿5,828
฿6,645 total
includes taxes & fees
2 Apr - 3 Apr
Staybridge Suites Scottsdale - Talking Stick by IHG

Sleep Inn North Scottsdale near Mayo Clinic

Sleep Inn North Scottsdale near Mayo Clinic
2.5 star property
Paradise Valley Village, 13.6 km from Mayo Clinic
8.8 out of 10, Excellent, (1,012 reviews)
"Wonderful breakfast and super relaxing pool area. Would visit again."
United States
Ester
The price is ฿3,877
฿4,384 total
includes taxes & fees
6 Apr - 7 Apr
Sleep Inn North Scottsdale near Mayo Clinic

Hilton Vacation Club Scottsdale Villa Mirage

Hilton Vacation Club Scottsdale Villa Mirage
3.5 star property
13.1 km from Mayo Clinic
8.6 out of 10, Excellent, (1,010 reviews)
"overall it was a wonderful stay!"
United States
Todd
The price is ฿4,550
฿6,125 total
includes taxes & fees
25 Mar - 26 Mar
Hilton Vacation Club Scottsdale Villa Mirage

Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort
3.5 star property
11.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,019 reviews)
"Staff was friendly, beautiful place to stay. "
United States
Ron
The price is ฿5,933
฿7,707 total
includes taxes & fees
6 Apr - 7 Apr
Hilton Vacation Club Scottsdale Links Resort

Sonesta Simply Suites Phoenix Scottsdale

Sonesta Simply Suites Phoenix Scottsdale
2.5 star property
8.7 km from Mayo Clinic
8.0 out of 10, Very good, (1,004 reviews)
"Super friendly staff"
United States
robert
The price is ฿2,756
฿3,141 total
includes taxes & fees
3 Apr - 4 Apr
Sonesta Simply Suites Phoenix Scottsdale

Home2 Suites by Hilton Scottsdale Old Town

Home2 Suites by Hilton Scottsdale Old Town
2.5 star property
Downtown Scottsdale, 16.7 km from Mayo Clinic
8.8 out of 10, Excellent, (1,018 reviews)
"Staff was friendly and the rooms were clean."
United States
Carl
The price is ฿6,165
฿7,027 total
includes taxes & fees
5 Apr - 6 Apr
Home2 Suites by Hilton Scottsdale Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Tom's Thumb Trail and Tonto Verde Golf Club.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and Arizona Boardwalk while you're sightseeing around the area.