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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.4 out of 10, Very good, (1,097 reviews)
"Awesome place to stay. "
United States
Tyler
The price is ฿2,473
฿2,818 total
includes taxes & fees
11 Jun - 12 Jun
Sonesta Select Scottsdale at Mayo Clinic Campus

SureStay By Best Western Phoenix Airport

SureStay By Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (2,124 reviews)
"nice hotel, rooms were clean"
United States
Francisco
The price is ฿2,583
฿2,920 total
includes taxes & fees
24 May - 25 May
SureStay By Best Western Phoenix Airport

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,647 reviews)
"Great stay, very clean and staff was great"
Canada
Daniel Di
The price is ฿4,384
฿5,930 total
includes taxes & fees
7 Jun - 8 Jun
Talking Stick Resort

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
2.5 star property
27.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,841 reviews)
"Great place to stay!"
United States
Beth
The price is ฿3,138
฿3,548 total
includes taxes & fees
24 May - 25 May
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,002 reviews)
"Close to Phoenix but far enough that it was quiet and peaceful!"
United States
Danielle
The price is ฿2,751
฿3,141 total
includes taxes & fees
10 Jun - 11 Jun
Fountain Park Hotel, BW Signature Collection

Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
23.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,093 reviews)
"As always, great place. "
United States
Jeffrey
The price is ฿3,106
฿3,543 total
includes taxes & fees
19 Jun - 20 Jun
Hyatt Place Tempe Phoenix Airport

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,002 reviews)
"Clean room, helpful staff, nice pool and hot tub area"
United States
Donna Michelle
The price is ฿3,501
฿3,997 total
includes taxes & fees
1 Jun - 2 Jun
Inn at Eagle Mountain

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,001 reviews)
"Beautiful place."
United States
KEITH
The price is ฿3,410
฿5,813 total
includes taxes & fees
16 Jun - 17 Jun
Wekopa Casino Resort

Scottsdale Parkview Hotel

Scottsdale Parkview Hotel
3.5 star property
17.6 km from Mayo Clinic
7.8 out of 10, Good, (5,070 reviews)
"Nice stay "
United States
Jeremy
The price is ฿2,453
฿2,992 total
includes taxes & fees
28 May - 29 May
Scottsdale Parkview Hotel

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
3.0 star property
24.1 km from Mayo Clinic
8.2 out of 10, Very good, (1,761 reviews)
"Food was good "
United States
Witold
The price is ฿2,419
฿2,764 total
includes taxes & fees
3 Jun - 4 Jun
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,450 reviews)
"Nice atmosphere and service was great"
United States
Gaye
The price is ฿5,266
฿6,002 total
includes taxes & fees
3 Jun - 4 Jun
Hotel Valley Ho

Hilton Garden Inn Phoenix Airport

Hilton Garden Inn Phoenix Airport
3.0 star property
27.6 km from Mayo Clinic
8.8 out of 10, Excellent, (1,004 reviews)
"Comfortable, easy access to airport"
United States
Inna
The price is ฿2,922
฿3,304 total
includes taxes & fees
14 Jun - 15 Jun
Hilton Garden Inn Phoenix Airport

Country Inn & Suites by Radisson, Phoenix Airport, AZ

Country Inn & Suites by Radisson, Phoenix Airport, AZ
3.0 star property
25.2 km from Mayo Clinic
8.2 out of 10, Very good, (3,043 reviews)
"Nice place to stay for a good price "
United States
Alissa
The price is ฿2,574
฿2,911 total
includes taxes & fees
31 May - 1 Jun
Country Inn & Suites by Radisson, Phoenix Airport, AZ

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG
2.5 star property
20.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,020 reviews)
"Very clean hotel one of the best breakfast and friendly staff .."
Canada
Ronak
The price is ฿3,007
฿3,727 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Embassy Suites by Hilton Phoenix Tempe

Embassy Suites by Hilton Phoenix Tempe
3.5 star property
25.7 km from Mayo Clinic
8.4 out of 10, Very good, (1,012 reviews)
"Very clean, nice little happy hour and one of the best complimentary breakfast. "
United States
Donna
The price is ฿3,584
฿4,089 total
includes taxes & fees
14 Jun - 15 Jun
Embassy Suites by Hilton Phoenix Tempe

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,859 reviews)
"Breakfast was great every day I was there."
United States
Ian
The price is ฿3,207
฿3,665 total
includes taxes & fees
31 May - 1 Jun
Hyatt Place Phoenix/Mesa

SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs
2.5 star property
23.4 km from Mayo Clinic
8.2 out of 10, Very good, (1,797 reviews)
"Was in a good location and was a very nice hotel for the value."
United States
Michelle
The price is ฿2,452
฿2,802 total
includes taxes & fees
25 May - 26 May
SureStay Plus by Best Western Mesa Superstition Springs

Fairfield Inn & Suites by Marriott Tempe

Fairfield Inn & Suites by Marriott Tempe
3.0 star property
20.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (396 reviews)
"Great location, clean building, beautiful rooms, a little dated but for the price it worked. The staff was very friendly and helpful."
United States
Arnita
The price is ฿2,713
฿3,095 total
includes taxes & fees
24 May - 25 May
Fairfield Inn & Suites by Marriott Tempe

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
4.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,493 reviews)
"Great place, clean, great breakfast!"
United States
Kristin
The price is ฿3,596
฿4,066 total
includes taxes & fees
24 May - 25 May
Drury Inn & Suites Phoenix Airport

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,867 reviews)
"Room is clean/Enough parking/Nice breakfast"
United States
Shailaja
The price is ฿2,383
฿2,716 total
includes taxes & fees
7 Jun - 8 Jun
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Arizona Boardwalk and OdySea Aquarium while you're sightseeing around the area.