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17 Dec - 18 Dec
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18 Dec - 19 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Margnolles - Rhône hotels

Mediterranean cuisine
TRIBE Lyon Croix Rousse

TRIBE Lyon Croix Rousse

TRIBE Lyon Croix Rousse
4.0 star property
Margnolles - Rhône
9.0 out of 10, Wonderful, (147)
"Lovely hotel and very reasonable price "
United Kingdom
Beth
The price is ฿2,752
฿3,239 total
includes taxes & fees
4 Jan - 5 Jan 2026
TRIBE Lyon Croix Rousse
Exterior
Kyriad Lyon Est - Genas Eurexpo

Kyriad Lyon Est - Genas Eurexpo

Kyriad Lyon Est - Genas Eurexpo
3.0 star property
13.1 km from Margnolles - Rhône
8.4 out of 10, Very good, (599)
"Really enjoyed our stay; felt like home away from home. All the staff are very lovely and polite. The restaurant provides good food especially their breakfast. There's free parking as well unlike other hotels. "
United Kingdom
Patricia
The price is ฿1,749
฿2,046 total
includes taxes & fees
28 Dec - 29 Dec
Kyriad Lyon Est - Genas Eurexpo
Lobby
NH Lyon Airport

NH Lyon Airport

NH Lyon Airport
4.0 star property
19.9 km from Margnolles - Rhône
9.4 out of 10, Exceptional, (1002)
"Staff were wonderful and friendly, very welcoming. Room was great, had everything I needed"
United Kingdom
Lauren
The price is ฿3,666
฿4,186 total
includes taxes & fees
21 Dec - 22 Dec
NH Lyon Airport
Daily buffet breakfast (EUR 19.5 per person)
Hôtel Mercure Lyon Centre Lumière

Hôtel Mercure Lyon Centre Lumière

Hôtel Mercure Lyon Centre Lumière
4.0 star property
4.8 km from Margnolles - Rhône
8.4 out of 10, Very good, (380)
"Perfect location for the meetings we attended. Close to metro and restaurants"
United States
Becky
The price is ฿2,888
฿3,389 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hôtel Mercure Lyon Centre Lumière
Desk, soundproofing, free WiFi
Le Lumière

Le Lumière

Le Lumière
3.0 star property
5 km from Margnolles - Rhône
9.2 out of 10, Wonderful, (64)
"Very nice property. Staff was very friendly."
United States
Minerva
The price is ฿2,059
฿2,403 total
includes taxes & fees
28 Dec - 29 Dec
Le Lumière
Classic Room with balcony including self-service snacks and drinks at the Club | Premium bedding, in-room safe, desk, soundproofing
OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre
4.0 star property
2.4 km from Margnolles - Rhône
9.0 out of 10, Wonderful, (1008)
"Fantastic hotel, welcoming staff. "
Canada
Carol
The price is ฿3,475
฿4,034 total
includes taxes & fees
19 Dec - 20 Dec
OKKO Hotels Lyon Centre
City view from property
Novotel Lyon Gerland Musée des Confluences

Novotel Lyon Gerland Musée des Confluences

Novotel Lyon Gerland Musée des Confluences
4.0 star property
6.1 km from Margnolles - Rhône
8.2 out of 10, Very good, (1003)
"Great location for trip through France "
United Kingdom
Colin
The price is ฿2,654
฿3,131 total
includes taxes & fees
11 Jan - 12 Jan 2026
Novotel Lyon Gerland Musée des Confluences
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon
4.0 star property
3.6 km from Margnolles - Rhône
9.2 out of 10, Wonderful, (1004)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Desk, iron/ironing board, free WiFi, bed sheets
Residhome Lyon Gerland

Residhome Lyon Gerland

Residhome Lyon Gerland
3.0 star property
5.5 km from Margnolles - Rhône
8.4 out of 10, Very good, (228)
"It was okay for family and near to metro station."
United Kingdom
Anton
The price is ฿2,089
฿2,436 total
includes taxes & fees
4 Jan - 5 Jan 2026
Residhome Lyon Gerland
Indoor spa tub
B&B Home Lyon Centre Berthelot

B&B Home Lyon Centre Berthelot

B&B Home Lyon Centre Berthelot
5.1 km from Margnolles - Rhône
8.4 out of 10, Very good, (830)
"The stay was very comfortable and everything was clean, and even got to enjoy the jacuzzi and sauna for one night! Was easy to get to my train station for travel the next day. "
United States
Gail
B&B Home Lyon Centre Berthelot
Bar (on property)
Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette
4.0 star property
2.7 km from Margnolles - Rhône
8.8 out of 10, Excellent, (1002)
"Nice workout facility with dipping pool. "
Canada
Sue
The price is ฿3,431
฿3,986 total
includes taxes & fees
4 Jan - 5 Jan 2026
Mercure Lyon Centre Saxe Lafayette
Daily continental breakfast (EUR 14 per person)
Q7 Lodge Lyon 7

Q7 Lodge Lyon 7

Q7 Lodge Lyon 7
4.0 star property
5.4 km from Margnolles - Rhône
8.4 out of 10, Very good, (502)
"Rooms were larger than others we stayed at in Europe. Room was clean, staff was friendly and it was located in what felt like a quiet safe neighborhood. If you’re looking to spend lots of time in Old Lyon or City Center you’d be better off choosing a hotel closer to that area."
Canada
kate
The price is ฿2,331
฿2,776 total
includes taxes & fees
19 Dec - 20 Dec
Q7 Lodge Lyon 7
Lobby sitting area
The Ruck Hotel

The Ruck Hotel

The Ruck Hotel
4.0 star property
6.7 km from Margnolles - Rhône
9.0 out of 10, Wonderful, (208)
"Wasn’t a very good breakfast choice , staff were very helpful and efficient "
United Kingdom
yasmin
The price is ฿4,904
฿5,606 total
includes taxes & fees
31 Dec - 1 Jan 2026
The Ruck Hotel
Breakfast, lunch, dinner served; Regional cuisine
Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon
4.0 star property
3 km from Margnolles - Rhône
8.4 out of 10, Very good, (1002)
"It was great. The room was clean and comfortable. The staff were helpful and friendly"
United States
Glenn
The price is ฿4,104
฿4,726 total
includes taxes & fees
4 Jan - 5 Jan 2026
Radisson Blu Hotel Lyon
Exterior
ibis Styles Lyon Confluence

ibis Styles Lyon Confluence

ibis Styles Lyon Confluence
3.0 star property
4.9 km from Margnolles - Rhône
8.2 out of 10, Very good, (534)
"It wasn’t clear when we booked this hotel that it was right next to a constantly busy main road so it was noisy all night. The food was okay. We only had breakfast there and there wasn’t a lot of choice. The staff in the breakfast area were not helpful. "
United Kingdom
Susan
The price is ฿3,071
฿3,517 total
includes taxes & fees
9 Jan - 10 Jan 2026
ibis Styles Lyon Confluence
Exterior
Intercontinental Lyon Hotel Dieu by IHG

Intercontinental Lyon Hotel Dieu by IHG

Intercontinental Lyon Hotel Dieu by IHG
5.0 star property
3.1 km from Margnolles - Rhône
9.4 out of 10, Exceptional, (503)
"Great location in historic building. Excellent food and drink options."
United States
Ronald
The price is ฿10,158
฿11,467 total
includes taxes & fees
21 Dec - 22 Dec
Intercontinental Lyon Hotel Dieu by IHG
Meeting facility
Novotel Lyon Centre Confluence Bord de Saone

Novotel Lyon Centre Confluence Bord de Saone

Novotel Lyon Centre Confluence Bord de Saone
4.0 star property
5.4 km from Margnolles - Rhône
8.8 out of 10, Excellent, (872)
"Breakfast was excelent. "
United States
Francisco J
The price is ฿3,452
฿4,009 total
includes taxes & fees
4 Jan - 5 Jan 2026
Novotel Lyon Centre Confluence Bord de Saone
Executive Studio | Private kitchen | Fridge, microwave, stovetop, coffee/tea maker
Appart'city Classic Lyon Part Dieu Villette

Appart'city Classic Lyon Part Dieu Villette

Appart'city Classic Lyon Part Dieu Villette
3.0 star property
3.7 km from Margnolles - Rhône
8.0 out of 10, Very good, (102)
"I enjoyed my stay. The room was clean and staff were friendly. It's near the train station and there's a bus across the street to take you to the old town."
Canada
Marie Helene
The price is ฿2,105
฿2,454 total
includes taxes & fees
21 Dec - 22 Dec
Appart'city Classic Lyon Part Dieu Villette
Courtyard view
Académie Hôtel Lyon

Académie Hôtel Lyon

Académie Hôtel Lyon
4.0 star property
2.5 km from Margnolles - Rhône
9.4 out of 10, Exceptional, (203)
"Clean room, nice staff. "
Canada
Pamela
The price is ฿3,993
฿4,604 total
includes taxes & fees
12 Jan - 13 Jan 2026
Académie Hôtel Lyon
Reception
Hôtel Le Roosevelt

Hôtel Le Roosevelt

Hôtel Le Roosevelt
4.0 star property
2 km from Margnolles - Rhône
9.4 out of 10, Exceptional, (203)
"Room spotless, staff lovely "
United Kingdom
Jack
The price is ฿3,560
฿4,128 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hôtel Le Roosevelt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Margnolles - Rhône

Find the best Margnolles - Rhône areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Place Carnot – discover Lyon City Centre, a destination also famous for its shopping.

Lyon showing a city, a river or creek and a statue or sculpture

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour Square which includes a statue or sculpture, a river or creek and a bridge

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

2nd Arrondissement

Travellers love 2nd Arrondissement for its popular shops, and you can see more of Lyon by jumping on the metro at Place des Archives or Sainte-Blandine Tram Stop. You might spend time checking out top sights like Place Carnot and Lyon Confluence Shopping Center.

Top Margnolles - Rhône Hotel Reviews

Bikube Lyon

Bikube Lyon

10/10 Excellent
"The room is very clean and modern- looks brand new! A clever use of space with a well equipped kitchen and an immaculate bathroom with very good shower. The staff are super friendly and helpful. There is a metro station close by which connects with the centre of Lyon. There is a small supermarket 5 mins walk away to buy stuff for breakfast etc "
Kate 3-night trip
Posted 10 days ago
Bikube Lyon
Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

10/10 Excellent
"It was great. The room was clean and comfortable. The staff were helpful and friendly"
Glenn 1-night trip
Posted 1 month ago
Radisson Blu Hotel Lyon

Explore a world of travel with Expedia

Frequently asked questions

What is Margnolles - Rhône like?
Travellers are sure to enjoy a stay in Caluire-et-Cuire's Margnolles - Rhône neighbourhood.
What's a favourite hotel to stay in Margnolles - Rhône?
Based on Expedia customer reviews, TRIBE Lyon Croix Rousse is the highest ranked property in Margnolles - Rhône. This hotel offers a restaurant and a fitness centre.
How many hotels are there in the Margnolles - Rhône area?
When you want to find places to stay in Caluire-et-Cuire, start by booking one of Expedia's 8 hotels and other accommodation options in Margnolles - Rhône.
If I need to cancel my hotel reservation in Margnolles - Rhône, will I receive a refund?
Yes! Most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to review the best options available in Margnolles - Rhône.
What can I see and do in this Caluire-et-Cuire neighbourhood?
A few places to visit in the area around Margnolles - Rhône include Interpol Headquarters, Contemporary Art Museum and Le Pharaon Casino. While you're out sightseeing in Caluire-et-Cuire, make sure that you visit other sights such as Porte des Enfants du Rhône or Maison des Canuts.