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Check prices for these dates

In two weeks
26 Dec - 28 Dec
In two months
6 Feb - 8 Feb
In three months
6 Mar - 8 Mar
In four months
3 Apr - 5 Apr

Our top choices for La Serena holiday rentals

32-inch flat-screen TV with cable channels, first-run films
Domos Dream hotel cabañas

Camping in La Serena

2.0 star property
8.0 out of 10, Very good, (3)
"It was far away."
Mexico
Sergio
The price is ฿2,527
฿2,527 total
11 Dec - 12 Dec
Domos Dream hotel cabañas
Front of property
Apart Hotel y Cabañas Vegasur

Aparthotel in La Serena

3.0 star property
8.6 out of 10, Excellent, (93)
"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."
Chile
Martin
Apart Hotel y Cabañas Vegasur
Outdoor pool, pool loungers
Apart Hotel Gran Pacifico

Aparthotel in La Serena

3.0 star property
8.6 out of 10, Excellent, (40)
"En gral buena eleccion"
Argentina
Javier
Apart Hotel Gran Pacifico
Family Cabin, 2 Bedrooms | Private kitchen | Full-sized fridge, microwave, oven, electric kettle
Cabañas de la Costa

Cabin in La Serena

3.0 star property
10.0 out of 10, Exceptional, (1)
"They were very hospitable. And I would recommend it to anybody that comes to coquimbo."
United States
Erwin
The price is ฿4,239
฿4,239 total
1 Jan - 2 Jan 2026
Cabañas de la Costa
Beach nearby, sun-loungers, beach umbrellas, beach massages
Cosmopolita

Apartment in La Serena

3.0 star property
10.0 out of 10, Exceptional, (2)
"Highly recommend! The apartment was great and comfortable with everything you need and in a great location, and the owner Yanitza is incredibly nice and helpful and can tell you many things to do and see and is a very friendly person who makes you feel welcome."
United States
brett
Cosmopolita
Basic Apartment | 3 bedrooms, free WiFi
Increíble depto a pasos de Av. del Mar

Apartment in La Serena

2.5 star property
6.0 out of 10, (1)
"The room had great view but was not very clean. Mold on shower curtins, stained sheets and pillow cases."
Canada
Gonzalo
Increíble depto a pasos de Av. del Mar
3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas
Cabaña Villa Los Plátanos

Cabin in La Serena

3.0 star property
10.0 out of 10, Exceptional, (2)
The price is ฿2,175
฿2,175 total
11 Dec - 12 Dec
Cabaña Villa Los Plátanos
Classic Apartment, Ocean View | Private kitchen
Depto Serena Golf

Apartment in La Serena

2.0 star property
The price is ฿7,220
฿9,283 total
21 Dec - 22 Dec
Depto Serena Golf
Porch
Piedra Negra

Apartment in La Serena

3.0 star property
Piedra Negra
Apartment | Beach | Beach nearby
Oceana Suites Laguna del Mar

Apartment in La Serena

3.0 star property
2.0 out of 10, (1)
"No tenían el departmento que arrendamos y me tuvieron que mover a otro. Todo fue a última hora, si yo no contacto para las llaves no se enteran que teníamos una reserva. "
Canada
Daniela
Oceana Suites Laguna del Mar
Front of property
Qamawi

Cabin in La Serena

2.5 star property
Qamawi
Interior detail
Departamento Edificio La Alhambra 030 - La Serena

Apartment in La Serena

2.5 star property
Departamento Edificio La Alhambra 030 - La Serena
Apartment, 2 Bedrooms, Private Bathroom | Living area | Flat-screen TV
8.- HNA Playa Pacifico IV

Apartment in La Serena

3.0 star property
10.0 out of 10, Exceptional, (1)
8.- HNA Playa Pacifico IV
Exterior
761 Av. Pacifico

Apartment in La Serena

3.5 star property
761 Av. Pacifico
Superior Cabin, 2 Bedrooms, 2 Bathrooms, Garden Area | View from room
Cabañas 4 Esquinas

Cabin in La Serena

3.0 star property
8.2 out of 10, Very good, (19)
"Descepcionante, instalaciones sin renovar.. caro para lo que ofrecen... fome, no volvería "
Chile
Anonymous traveller
Cabañas 4 Esquinas
Apartment | Property grounds
Oceana Suites Distrito Verde

Apartment in La Serena

3.0 star property
Oceana Suites Distrito Verde
Property grounds
Departamento Molina

Apartment in La Serena

3.0 star property
Departamento Molina
Apartamento 1 dormitorio con vista al mar (1124) | Balcony
Condominio Mirador El Faro

Condo in La Serena

3.0 star property
7.8 out of 10, Good, (10)
"Es handelt sich nicht um ein Hotel, sondern um eine Eigentumswohnung in einem großen Wohnkomplex mit zweckmäßiger Einrichtung, in der Näche des Leuchtturms. Das WLAN hat nicht funktioniert. Eingangstür mit Zahlenschloss fühlte sich nicht sicher an. "
Germany
H.Weigelt
Condominio Mirador El Faro
Balcony
Depto Edificio Ecovista

Apartment in La Serena

3.0 star property
Depto Edificio Ecovista
Property grounds
Depto en Edificio Don Victor

Apartment in La Serena

3.0 star property
Depto en Edificio Don Victor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Serena Hotel Reviews

Hotel Diego de Almagro La Serena Express

Hotel Diego de Almagro La Serena Express

10/10 Excellent
"Great property with lots of amenities. Only thing that l missed was an iron for my shirts. Other than that l give it a 10"
Cesar 2-night trip
Posted 9 days ago
Hotel Diego de Almagro La Serena Express

Find out more about La Serena

Search for holiday rentals in La Serena on Expedia! You can easily find your home rentals, villas, holiday apartments in La Serena using one of the methods below:

  • View our selection of featured holiday rentals in La Serena
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  • Enter your travel dates to view the best deals on holiday rentals in La Serena while they last

Look no further and take a look at our great range of rental properties in La Serena!

Frequently asked questions

Can I find a holiday rental in La Serena?

Yes, there are holiday rentals in La Serena close to Jardin del Corazon, or you can select a more secluded option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

How many holiday rentals will I find in La Serena?

With 17 Expedia holiday rentals, you're guaranteed to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum, whereas Jardin del Corazon and El Faro Beach are a couple of picturesque spots to enjoy the outdoors. While here, Mall Plaza La Serena and La Serena Lighthouse are other places worth a visit.

What are holiday rentals like in La Serena?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Serena. Holiday rentals feature extras such as kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a clean environment, a holiday rental can offer a sense of security away from shared hotel lifts and busy lobbies while still allowing you a great travel experience. You'll also find more space in a holiday rental than in a standard hotel, which makes a holiday rental an attractive option for a small group gathering.