Find hotels in La Mesa, CA from ฿1,952

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Our top choices for La Mesa hotels

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.4 out of 10, Very good, (1002)
"Clean room, great breakfast, pleasant staff. It was comfortable. "
United States
Vonda
The price is ฿3,540
฿3,894 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus La Mesa San Diego

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1214)
"room was clean and staff very friendly"
United States
Charles
The price is ฿1,769
฿1,952 total
includes taxes & fees
28 Dec - 29 Dec
Heritage Inn La Mesa

Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego
2.0 star property
La Mesa
7.4 out of 10, Good, (980)
"Best Motel 6 I’ve ever been too! Clean marbel showers and comfortable beds!"
United States
Izaiah
The price is ฿2,672
฿2,944 total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 La Mesa, CA - San Diego

Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
La Mesa
8.2 out of 10, Very good, (456)
"Great Stay"
United States
Jazmin
The price is ฿4,071
฿4,486 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express La Mesa Near SDSU by IHG

Motel 6 La Mesa, CA

Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
"Place was decent a bit dusty in the room and the parking was very very tight but for a quick stay it was fine!"
United States
Trevor
The price is ฿2,797
฿3,076 total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 La Mesa, CA

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is ฿2,940
฿4,307 total
includes taxes & fees
7 Jan - 8 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2871)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is ฿5,470
฿8,035 total
includes taxes & fees
28 Dec - 29 Dec
Manchester Grand Hyatt San Diego

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (793)
"would stay again and recommend "
United States
Brendi
The price is ฿3,481
฿4,036 total
includes taxes & fees
4 Jan - 5 Jan 2026
The DEXTRO Little Italy, BW Premier Collection

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1639)
"Very peaceful resort "
United States
Camilla
Sycuan Casino Resort

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley
8.4 out of 10, Very good, (1914)
"Excellent location"
United States
Paolo
The price is ฿3,035
฿3,459 total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1954)
"Great location! Clean room, nice pool, good food, amazing view! "
United States
Elizabeth
The price is ฿5,438
฿7,939 total
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott Marquis San Diego Marina

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3161)
"Beautiful hotel"
United States
Jordan M.
The price is ฿5,286
฿7,558 total
includes taxes & fees
26 Dec - 27 Dec
Hard Rock Hotel San Diego

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1312)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is ฿4,576
฿6,662 total
includes taxes & fees
1 Jan - 2 Jan 2026
San Diego Mission Bay Resort

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
Point Loma
8.8 out of 10, Excellent, (1560)
"Staff was great, easy check in and great location"
United States
Alysa
The price is ฿3,704
฿4,258 total
includes taxes & fees
12 Jan - 13 Jan 2026
Best Western Plus Island Palms Hotel & Marina

Ayres Lodge Alpine

Ayres Lodge Alpine
3.0 star property
Alpine
9.2 out of 10, Wonderful, (1000)
"Large rooms,very clean, wonderful breakfast! "
United States
Becky
The price is ฿3,387
฿3,665 total
includes taxes & fees
3 Jan - 4 Jan 2026
Ayres Lodge Alpine

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego
8.2 out of 10, Very good, (1915)
"Great stay "
United States
Vanessa
The price is ฿2,598
฿2,986 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2931)
"Great boutique hotel!!"
United States
Maksim
Legacy Resort Hotel & Spa

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach
9.0 out of 10, Wonderful, (810)
"Good location, good basic breakfast, good parking, recommended. "
United States
Leyla
The price is ฿3,201
฿3,679 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3210)
"Great stay and location!"
United States
Jason
The price is ฿3,527
฿4,055 total
includes taxes & fees
25 Jan - 26 Jan 2026
Bay Club Hotel & Marina

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1422)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is ฿3,491
฿4,013 total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley
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Where to stay in La Mesa

Find the best La Mesa areas for the activities you enjoy most.

Mount Helix

If you're looking for some top things to see and do in Mount Helix and surrounding area, you can visit Mount Helix Park and The Magnolia.

Windsor Hills

While there might not be top attractions in Windsor Hills, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Stay near popular La Mesa attractions

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

View from Mount Helix, in La Mesa, near San Diego, California

Top La Mesa Hotel Reviews

More cheap stays in La Mesa

Frequently asked questions

What's the best place for a stay in La Mesa?
Best Western Plus La Mesa San Diego is a favourite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Holiday Inn Express La Mesa Near SDSU by IHG and Motel 6 La Mesa, CA as top choices for your stay. See all available top hotels, or vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
What's the best family accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Also, children of all ages will enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.
What is the favourite LGBTQ-friendly accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Heritage Inn La Mesa is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.
What's the best dog-friendly place to stay in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel for people travelling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet include Motel 6 La Mesa, CA - San Diego and Motel 6 La Mesa, CA. See more pet-friendly hotel accommodations in La Mesa.
What are some accommodation options with pools in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel with a pool, free buffet breakfast and free WiFi. View all hotels with pools in La Mesa.
What is staying in La Mesa like?
Families will find child-friendly activities in La Mesa, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its shopping, zoo and entertainment. Around the area, top sights include San Diego Zoo, Petco Park and Port of San Diego. In La Mesa, there are 160 hotels and other accommodation options to choose from. Find out more about La Mesa.
What is there to see in La Mesa?
A couple of favourite places to visit are Mount Helix Park and Computer Museum of America. You'll also find San Diego Zoo and Petco Park in the area. Take a look at what more there is to see and do in Expedia's La Mesa guide.
How should I get around La Mesa?
You can take advantage of metro transport at La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station. If you want to venture out around the area, you may want a rental car in La Mesa for your journey.
What's the seasonal weather in La Mesa?
The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.

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