Search Family-Friendly Hotels in La Mesa

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Check availability on La Mesa Family-Friendly Hotels

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for La Mesa family-friendly hotels

Blackout curtains, free WiFi, bed sheets
Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego
2.0 star property
La Mesa
7.4 out of 10, Good, (981)
"Best Motel 6 I’ve ever been too! Clean marbel showers and comfortable beds!"
United States
Izaiah
The price is ฿2,831
฿3,119 total
includes taxes & fees
4 Jan - 5 Jan 2026
Motel 6 La Mesa, CA - San Diego
Outdoor pool, pool umbrellas, pool loungers
Heritage Inn La Mesa

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1221)
"room was clean and staff very friendly"
United States
Charles
The price is ฿1,791
฿1,976 total
includes taxes & fees
4 Jan - 5 Jan 2026
Heritage Inn La Mesa
Suite, Multiple Beds, Kitchenette | Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
La Mesa
8.2 out of 10, Very good, (459)
"Great Stay"
United States
Jazmin
The price is ฿4,811
฿5,301 total
includes taxes & fees
19 Jan - 20 Jan 2026
Holiday Inn Express La Mesa Near SDSU by IHG
Blackout curtains, free WiFi, bed sheets
Motel 6 La Mesa, CA

Motel 6 La Mesa, CA

Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
"Place was decent a bit dusty in the room and the parking was very very tight but for a quick stay it was fine!"
United States
Trevor
The price is ฿3,145
฿3,460 total
includes taxes & fees
11 Jan - 12 Jan 2026
Motel 6 La Mesa, CA
Outdoor pool
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1015)
"Room and breakfast "
United States
Juan
The price is ฿2,926
฿3,376 total
includes taxes & fees
4 Jan - 5 Jan 2026
Crowne Plaza San Diego - Mission Valley by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"All was excellent thank you very much "
Camil 1-night trip
Posted 2 days ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

What's La Mesa like for family-friendly holidays?
The welcoming destination of La Mesa is a great choice if you've been considering a holiday with the children. The entertainment and cafes are just a couple of things that make this an attractive spot for a family holiday. Arrange a flight into San Diego, CA (SEE-Gillespie Field), which is the closest airport, or San Diego, CA (MYF-Montgomery Field), which is located 7.5 mi (12.1 km) from the city centre.
What's the best family accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly holiday in La Mesa?
The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.
What's there to see and do with your family in La Mesa?
While you are visiting La Mesa, you and the family may want to explore some interesting spots such as San Diego Zoo, Petco Park and Port of San Diego. Make sure that you have plenty of time to take in activities in the area such as Mission Bay, Mission Beach and San Ysidro Border Crossing.
What's the best way for us to get around La Mesa?
Walk to nearby metro stations such as La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station. If you'd like to venture out around the area, you may want to rent a car for your trip.