South Main Travel Guide

Houston

A city skyline with modern buildings and a park with a lake.
A modern urban street with a metro train, buildings, and a clear blue sky.

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

฿984
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston Museum of Natural Sciences: Planetarium Ticket

Houston Museum of Natural Sciences: Planetarium Ticket

฿394
per adult
80% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

฿2,626
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
Houston: Museum of Natural Science General Admission Ticket

Houston: Museum of Natural Science General Admission Ticket

฿821
per adult
98% of travellers recommend
Houston: Museum of Natural Science General Admission Ticket
The Official Houston City Tour

NASA's Space Center & Official Houston City Tour with tickets

฿3,579
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
Houston: Holocaust Museum Houston Entry Ticket

Houston: Holocaust Museum Houston Entry Ticket

฿723
per adult
90% of travellers recommend
Houston: Holocaust Museum Houston Entry Ticket
See all activities in Houston

Top hotels in South Main

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive Houston TX
The price is ฿3,056 per night from 3 Aug to 4 Aug
฿3,056
฿3,576 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, a 24-hour fitness centre and a 24-hour front desk. Our guests praise the helpful staff and ...
7/10 Good! (1,338 reviews)
"Clean room"

Reviewed on 13 Jul 2026

Wyndham Houston near NRG Park/Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
The price is ฿3,865 per night from 14 Jul to 15 Jul
฿3,865
฿4,522 total
14 Jul - 15 Jul
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
Club Quarters Hotel Downtown, Houston
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
The price is ฿3,092 per night from 19 Jul to 20 Jul
฿3,092
฿3,618 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this family-friendly hotel in Houston. Enjoy free Wi-Fi, an outdoor pool and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8/10 Very good! (164 reviews)
"Beautiful Place"

Reviewed on 13 Jul 2026

Grand Tuscany Hotel
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
The price is ฿4,254 per night from 31 Jul to 1 Aug
฿4,254
฿5,012 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
8.4/10 Very good! (4,270 reviews)
"."

Reviewed on 13 Jul 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
The price is ฿9,289 per night from 30 Jul to 31 Jul
฿9,289
฿11,831 total
30 Jul - 31 Jul
includes taxes & fees
Stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
9/10 Wonderful! (1,173 reviews)
"N/a"

Reviewed on 12 Jul 2026

Marriott Marquis Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
The price is ฿5,483 per night from 19 Jul to 20 Jul
฿5,483
฿6,415 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges and a rooftop terrace. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (3,861 reviews)
"Amazing stay,will visit again"

Reviewed on 13 Jul 2026

Blossom Hotel Houston, Curio Collection by Hilton
See all 7,275 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
A cityscape with modern skyscrapers and a park with trees and people.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A large, modern shopping mall with a glass ceiling and multiple levels.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

South Main Travel Guide