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Top Trending Hotels Near South Main, Houston

Hyatt Place Houston/Galleria

3.0 star property
8.8 out of 10, Excellent, (1030)
"Great place to stay in"
The price is ฿3,293
฿3,874 total
includes taxes & fees
29 Aug - 30 Aug
Hyatt Place Houston/Galleria

Hyatt Regency Houston West

3.5 star property
8.6 out of 10, Excellent, (1156)
"Beautiful lobby and friendly staff"
The price is ฿3,416
฿3,997 total
includes taxes & fees
29 Aug - 30 Aug
Hyatt Regency Houston West

Hotel ZaZa Houston Memorial City

4.0 star property
9.4 out of 10, Exceptional, (1004)
"Great celebration location for our 19th Anniversary "
Hotel ZaZa Houston Memorial City

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1132)
"It was quiet and close to our event. It was very clean and staff was helpful "
The price is ฿3,209
฿3,754 total
includes taxes & fees
2 Sept - 3 Sept
Wyndham Houston near NRG Park/Medical Center

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1007)
"Wonderful experience absolutely love my stay"
The price is ฿2,013
฿2,355 total
includes taxes & fees
11 Sept - 12 Sept
Quality Inn & Suites NRG Park - Medical Center

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (931)
"Great location, rooms were hot/warm. Needs a huge make over."
The price is ฿2,560
฿2,996 total
includes taxes & fees
1 Sept - 2 Sept
Wingate Houston near NRG Park/Medical Center

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (792)
"Will definitely be back again!"
The price is ฿2,528
฿2,958 total
includes taxes & fees
11 Sept - 12 Sept
Candlewood Suites Houston Medical Center by IHG

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1759)
"Had a quick stay here and would come back again!"
Hotel Zaza Houston Museum District

Hilton Garden Inn Houston/Bush Intercontinental Airport

3.0 star property
8.2 out of 10, Very good, (1009)
"Good Hotel clean and comfortable."
The price is ฿2,309
฿2,716 total
includes taxes & fees
30 Aug - 31 Aug
Hilton Garden Inn Houston/Bush Intercontinental Airport

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

3.0 star property
8.6 out of 10, Excellent, (1508)
"Nice place to stay and convenient to the airport. They also have a free shuttle. Staff was very helpful."
The price is ฿2,577
฿3,031 total
includes taxes & fees
3 Sept - 4 Sept
Hampton Inn & Suites Houston-Bush Intercontinental Aprt

The Moran CITYCENTRE

4.0 star property
9.0 out of 10, Wonderful, (1006)
"Nice hotel with surrounding restaurants and stores for shopping. "
The Moran CITYCENTRE

Hyatt Place Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (1557)
"Great place to stay "
The price is ฿3,863
฿4,603 total
includes taxes & fees
5 Sept - 6 Sept
Hyatt Place Houston Downtown

Blossom Hotel Houston

4.0 star property
9.0 out of 10, Wonderful, (3483)
"The hotel is wonderful and I loved it "
The price is ฿5,419
฿6,340 total
includes taxes & fees
26 Sept - 27 Sept
Blossom Hotel Houston

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (560)
"Very clean with good breakfast! "
The price is ฿3,338
฿3,906 total
includes taxes & fees
1 Sept - 2 Sept
Holiday Inn Express & Suites Houston – Downtown North by IHG

Houston Marriott South at Hobby Airport

3.5 star property
8.8 out of 10, Excellent, (1187)
"Great hotel "
The price is ฿2,697
฿3,244 total
includes taxes & fees
29 Aug - 30 Aug
Houston Marriott South at Hobby Airport

Americas Best Value Inn & Suites NE Houston Downtown I-610

2.0 star property
8.6 out of 10, Excellent, (609)
"Love my stay! Will def come back"
The price is ฿2,158
฿2,525 total
includes taxes & fees
31 Aug - 1 Sept
Americas Best Value Inn & Suites NE Houston Downtown I-610

Courtyard by Marriott Houston Intercontinental Airport

3.0 star property
9.0 out of 10, Wonderful, (1018)
"Clean hotel, very friendly and helpful staff."
The price is ฿3,278
฿3,836 total
includes taxes & fees
5 Sept - 6 Sept
Courtyard by Marriott Houston Intercontinental Airport

Hyatt Place Houston/Sugar Land

3.0 star property
8.8 out of 10, Excellent, (1681)
"Just a wonderful place iverall"
The price is ฿3,079
฿3,541 total
includes taxes & fees
21 Sept - 22 Sept
Hyatt Place Houston/Sugar Land

Thompson Houston, by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (187)
"I loved our stay at the Thompson we would definitely be back next time we are in the Houston Area ! "
The price is ฿8,232
฿11,016 total
includes taxes & fees
21 Sept - 22 Sept
Thompson Houston, by Hyatt

Hyatt Regency Houston Downtown

4.0 star property
9.2 out of 10, Wonderful, (1081)
"Perfect place to stay! "
The price is ฿5,477
฿6,608 total
includes taxes & fees
29 Aug - 30 Aug
Hyatt Regency Houston Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Houston

3 out of top 10 points of interest in this area

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Theater District

Restaurants and seafood restaurants are just a few things travellers like about Theater District. A stop by Wortham Center is also recommended if you've got time to explore the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Explore a world of travel with Expedia

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Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 55 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.