Photo by Hazem Abdul

Search Hotels in South Main, Houston

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Find properties with these dates

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Property class
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top Trending Hotels Near South Main, Houston

Exterior
Club Quarters Hotel Downtown, Houston
4.0 star property
8.2 out of 10, Very good, (3794)
"The only thing it took the water like 5-10 minutes to get hot"
The price is ฿3,837
฿4,490 total
includes taxes & fees
29 May - 30 May
Club Quarters Hotel Downtown, Houston
City view
Blossom Hotel Houston
4.0 star property
9.2 out of 10, Wonderful, (2099)
"5 star all around. We'll be back."
The price is ฿6,242
฿7,304 total
includes taxes & fees
21 May - 22 May
Blossom Hotel Houston
City view from property
The Whitehall Houston
4.0 star property
8.2 out of 10, Very good, (1008)
"Great location. We was close to everything and the highway. The only issue we had was the power going off and there was no back up generator, we had to wait until the problem was fixed.."
The price is ฿5,251
฿6,144 total
includes taxes & fees
11 May - 12 May
The Whitehall Houston
Save an average of 15% on thousands of hotels when you're signed in
Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
7.6 out of 10, Good, (1014)
"Nice property"
The price is ฿4,749
฿5,595 total
includes taxes & fees
3 Jun - 4 Jun
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis Houston
4.0 star property
8.6 out of 10, Excellent, (1004)
"the parking was a bit rough for handicap persons. the valet was full and the parking garage and parking lot was too far for me to walk "
The price is ฿8,556
฿11,165 total
includes taxes & fees
27 May - 28 May
Marriott Marquis Houston
Exterior
Hilton Americas-Houston
4.0 star property
9.2 out of 10, Wonderful, (1078)
"Beautiful hotel. Room and amenities were clean. Staff was fantastic "
The price is ฿6,523
฿7,718 total
includes taxes & fees
26 May - 27 May
Hilton Americas-Houston
Lobby
Cambria Hotel Houston Downtown Convention Center
3.0 star property
8.8 out of 10, Excellent, (1307)
"Real nice"
The price is ฿4,026
฿4,711 total
includes taxes & fees
27 May - 28 May
Cambria Hotel Houston Downtown Convention Center
Lobby sitting area
Hyatt Place Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (1272)
"Very clean and quiet "
The price is ฿5,258
฿6,246 total
includes taxes & fees
22 May - 23 May
Hyatt Place Houston Downtown
Exterior
The Royal Sonesta Houston Galleria
4.0 star property
8.0 out of 10, Very good, (1006)
"Property was amazing and clean will definitely be coming back."
The price is ฿6,593
฿8,616 total
includes taxes & fees
11 May - 12 May
The Royal Sonesta Houston Galleria
Suite, 1 King Bed, City View | View from room
Hotel Derek
4.0 star property
6.4 out of 10, (2091)
"$30 to $40 to park your car The Hotel is great but high service fees and parking price makes the Hotel Derek $100 more than advertised"
The price is ฿4,083
฿5,725 total
includes taxes & fees
12 May - 13 May
Hotel Derek
City view
Hyatt Regency Houston
4.0 star property
9.0 out of 10, Wonderful, (1555)
"Location was great & convenient "
The price is ฿4,737
฿5,768 total
includes taxes & fees
10 May - 11 May
Hyatt Regency Houston
Outdoor pool
HYATT house Houston/Galleria
3.0 star property
8.4 out of 10, Very good, (2103)
"Very nice stay, clean rooms and friendly employees! Safe parking and walking stores."
The price is ฿4,168
฿4,877 total
includes taxes & fees
11 May - 12 May
HYATT house Houston/Galleria
Outdoor pool, pool cabanas (surcharge), pool umbrellas
The Post Oak Hotel at Uptown Houston
5.0 star property
9.6 out of 10, Exceptional, (605)
"Wonderful stay. Great experience as usual. The spa was amazing. "
The price is ฿20,563
฿24,059 total
includes taxes & fees
19 May - 20 May
The Post Oak Hotel at Uptown Houston
Outdoor banquet area
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.2 out of 10, Very good, (639)
"Very welcoming "
The price is ฿5,545
฿7,336 total
includes taxes & fees
26 May - 27 May
C. Baldwin, Curio Collection by Hilton
Lobby
Hyatt Place Houston Medical Center
3.0 star property
9.0 out of 10, Wonderful, (625)
"Room had dead bugs around lamp by TV. Other than this the room was very nice."
The price is ฿4,594
฿5,375 total
includes taxes & fees
12 May - 13 May
Hyatt Place Houston Medical Center
Lobby
Hyatt Place Houston/Galleria
3.0 star property
8.2 out of 10, Very good, (1508)
"Safe and Good location"
The price is ฿3,897
฿4,584 total
includes taxes & fees
27 May - 28 May
Hyatt Place Houston/Galleria
Outdoor pool, pool umbrellas, pool loungers
Hyatt Regency Houston/Galleria
4.0 star property
8.4 out of 10, Very good, (1426)
"The staff was amazing and very professional. Wonderful atmosphere and very clean. Would definitely recommend "
The price is ฿5,542
฿6,527 total
includes taxes & fees
2 Jun - 3 Jun
Hyatt Regency Houston/Galleria
Outdoor pool, pool umbrellas
Courtyard by Marriott Houston Medical Center/NRG Park
3.0 star property
8.4 out of 10, Very good, (1007)
"Decent stay "
The price is ฿3,714
฿4,370 total
includes taxes & fees
26 May - 27 May
Courtyard by Marriott Houston Medical Center/NRG Park
Property amenity
Holiday Inn Houston Downtown, an IHG Hotel
3.0 star property
8.4 out of 10, Very good, (1006)
"Good stay"
The price is ฿3,808
฿5,100 total
includes taxes & fees
24 May - 25 May
Holiday Inn Houston Downtown, an IHG Hotel
International cuisine
InterContinental Houston, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (1003)
"The staff was excellent! "
The price is ฿5,899
฿7,453 total
includes taxes & fees
11 May - 12 May
InterContinental Houston, an IHG Hotel
Don't see what you're looking for?
See all available properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

Hotels in top Houston neighborhoods Learn more about South Main

South Main hotels information

Number of reviews
27,065
Accommodation
6,625 hotels
Lowest Price
฿3,714
Highest Price
฿20,563

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 90 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.

South Main Hotel Reviews