South Central Houston Travel Guide
Houston
Visit South Central Houston
Popular places to visit
Rice University
Enjoy the student vibe when you visit Rice University during your travels in Houston. Experience the area's acclaimed theatre scene and lively festivals.
University of Houston
Take a campus tour or just explore the area of University of Houston during your travels in Houston. Experience the lively festivals and acclaimed theatre scene in this vibrant area.
Houston Zoo
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
Houston Methodist Hospital
If Houston Methodist Hospital is what brings you to town, hopefully you'll have a chance to explore more of Houston.
Houston Natural Science Museum
You can spend time browsing the exhibits at Houston Natural Science Museum during your trip to Houston. Experience the area's acclaimed theatre scene and lively festivals.
Texas Children's Hospital
If Texas Children's Hospital is what brings you to town, hopefully you'll have a chance to explore more of Houston.
Things to do
Houston: Holocaust Museum Houston Entry Ticket
Houston: Houston Botanic Garden Entry Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center
Top hotels in South Central Houston
Hilton Houston Plaza/Medical Center
Staff is extremely hospitable.
Reviewed on 19 Jan 2026
Hotel Zaza Houston Museum District
Impeccable! Great stay. Great service and staff and valet. They upped the southern hospitality and I will definitely come back to stay again.
Reviewed on 18 Jan 2026
The Westin Houston Medical Center/Museum District
Every was great
Reviewed on 13 Jan 2026
Downtowner Inns - Houston Downtown
Staff was helpful
Reviewed on 20 Jan 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Staff was great, room was clean and perfect location for our needs. Were there for medical appointment and if we ever need to go back will definitely stay again.
Reviewed on 22 Jan 2026
InterContinental Houston by IHG
Great staff, beautiful lobby, comfortable and clean room
Reviewed on 23 Jan 2026
Other neighbourhoods around South Central Houston
Greater Third Ward
If you're spending time in Greater Third Ward, check out sights like Carl Lewis International Track and Field Complex or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Houston Fire Museum and Midtown Arts and Theater Center Houston are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Jesse H. Jones Hall – discover Downtown Houston, a destination also famous for its sports teams.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
