South Central Houston Travel Guide
Houston
Visit South Central Houston
Stay near popular South Central Houston attractions
Things to do
Houston: Space Center Houston Admission Ticket
฿991
per adult
92% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
฿397
per adult
80% of travellers recommend
Houston: Holocaust Museum Houston Entry Ticket
฿728
per adult
90% of travellers recommend
Houston's Official City & Mural Tour!
฿1,322
per adult
88% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
฿3,274
per adult
92% of travellers recommend
Top hotels in South Central Houston
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
The price is ฿7,676 per night from 17 Aug to 18 Aug
฿7,676
฿10,291 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is ฿2,703 per night from 7 Sept to 8 Sept
฿2,703
฿3,200 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.4/10 Very good! (2,099 reviews)
"The room was great , not to far from Md anderson , was really disappointed in a restaurant not to order food & sit down Had to order food at Starbucks , bread was very hard , not a lot of food choices"
Reviewed on 14 Aug 2026
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
The price is ฿4,761 per night from 6 Sept to 7 Sept
฿4,761
฿5,926 total
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,182 reviews)
"Great location. Nice staff. Good restaurant. Easy parking. Unique elevator system that works really well."
Reviewed on 14 Aug 2026
InterContinental Houston by IHG
6750 Main St Houston TX
The price is ฿5,336 per night from 29 Aug to 30 Aug
฿5,336
฿6,906 total
29 Aug - 30 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
Houston Marriott Medical Center/Museum District
6580 Fannin Street Houston TX
The price is ฿4,479 per night from 28 Aug to 29 Aug
฿4,479
฿6,292 total
28 Aug - 29 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,000 reviews)
"Always my go to for stays during medical issues with parents."
Reviewed on 11 Aug 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
The price is ฿4,049 per night from 22 Aug to 23 Aug
฿4,049
฿4,738 total
22 Aug - 23 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
8.4/10 Very good! (658 reviews)
"Very clean room, the staff very nice, professional and friendly, breakfast was good, shuttle available to MD Anderson"
Reviewed on 14 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Central Houston
Find the best South Central Houston areas for the activities you enjoy most.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or The Chapel of St. Basil while you're exploring the area.
