South Central Houston Travel Guide

Houston

South Central Houston
South Central Houston
South Central Houston
South Central Houston
South Central Houston


Top hotels in South Central Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is ฿7,087 per night from 19 Apr to 20 Apr
฿7,087
฿9,761 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
This was such a wonderful experience from the booking, checkin, ambiance, the staff, and the peaceful rest that I received. I will definitely share with friends and plan to return.

Reviewed on 15 Apr 2026

Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is ฿4,133 per night from 19 Apr to 20 Apr
฿4,133
฿4,872 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.4/10 Very Good! (1,878 reviews)
Was called handicap room, however my husband who is in a wheelchair, couldn’t get in shower and barely to toilet. No microwave in room, but they did bring one.

Reviewed on 14 Apr 2026

Hilton Houston Plaza/Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is ฿4,867 per night from 19 Apr to 20 Apr
฿4,867
฿6,058 total
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,142 reviews)
Very pleasant stay with family. Courteous staff, good food, decent fitness center.

Reviewed on 15 Apr 2026

The Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is ฿5,483 per night from 18 Apr to 19 Apr
฿5,483
฿7,055 total
18 Apr - 19 Apr
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,002 reviews)
I've stayed at Intercontinental several times in the past including my honeymoon and have had a great experience. However, my experience at the Houston location wasn't as smooth. To start, the bell man was great, he was personable and was ready to help us. We had 4 big luggages and he was ready and ...

Reviewed on 13 Apr 2026

InterContinental Houston by IHG
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
The price is ฿3,915 per night from 17 May to 18 May
฿3,915
฿4,581 total
17 May - 18 May
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
8.4/10 Very Good! (558 reviews)
Easy parking. Breakfast buffet was better than most, cheerful staff, and the pot of coffee brought out quick and hot was nice.

Reviewed on 15 Apr 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

2 out of 5
2419 Riverside Dr Houston TX
The price is ฿3,167 per night from 18 Apr to 19 Apr
฿3,167
฿3,706 total
18 Apr - 19 Apr
includes taxes & fees
Stay at this motel in Houston. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8/10 Very Good! (1,002 reviews)
Shower water pressure was not always present

Reviewed on 12 Apr 2026

Americas Best Value Inn Medical Center Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Central Houston

Greater Third Ward

Greater Third Ward

If you're spending time in Greater Third Ward, check out sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

Greater Third Ward
Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.

Midtown

Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Houston Fire Museum and Midtown Arts and Theater Center Houston are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.

Midtown
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East Downtown Houston

1/5(1 area review)

The restaurants and live music are just a few things visitors like about East Downtown Houston. Shell Energy Stadium and Giant Beatles Statues are worthwhile spots to check out, and you can hop on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the larger area.

East Downtown Houston
Museum District

Museum District

Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.

Museum District
Houston Central Business District

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Houston Central Business District
Downtown Houston

Downtown Houston

4/5(25 area reviews)

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

Downtown Houston


South Central Houston Travel Guide