South Central Houston Travel Guide

Houston

TMC
TMC
Taken from the back parking garage.
Taken along bike trail.
Random structure in the museum district.

Popular places to visit

Things to do


Top hotels in South Central Houston

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is ฿3,107 per night from 16 Jan to 17 Jan
฿3,107
฿3,672 total
16 Jan - 17 Jan
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.2/10 Very Good! (1,820 reviews)
Room was nice and newly renovated. Check in was a breeze. Sleep was comfortable!

Reviewed on 12 Jan 2026

Hilton Houston Plaza/Medical Center
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St Houston TX
The price is ฿2,671 per night from 15 Jan to 16 Jan
฿2,671
฿3,125 total
15 Jan - 16 Jan
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Toyota Center and NRG Stadium are located nearby.
7.6/10 Good! (42 reviews)
Room was nice, clean and close to midtown

Reviewed on 26 Dec 2025

Downtowner Inns - Houston Downtown
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Stay at this luxury aparthotel in Houston. Enjoy free Wi-Fi, a full-service spa and a rooftop terrace. Our guests praise the helpful staff in their reviews. ...
8.8/10 Excellent! (1,881 reviews)
Extremely helpful staff, excellent service. Location is convenient to everything.

Reviewed on 12 Jan 2026

Hotel Zaza Houston Museum District
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is ฿4,517 per night from 25 Jan to 26 Jan
฿4,517
฿5,622 total
25 Jan - 26 Jan
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,058 reviews)
Every was great

Reviewed on 13 Jan 2026

The Westin Houston Medical Center/Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
The price is ฿2,874 per night from 7 Feb to 8 Feb
฿2,874
฿3,363 total
7 Feb - 8 Feb
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
8.2/10 Very Good! (494 reviews)
Staff was friendly despite being very busy they took their time with each person checking in to make sure they had what they needed. Room was clean and comfortable. We only stayed one evening had a drink from the bar, very nice bartender and wait staff for breakfast were nice and friendly. Overall ...

Reviewed on 9 Jan 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is ฿4,920 per night from 18 Jan to 19 Jan
฿4,920
฿6,387 total
18 Jan - 19 Jan
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,006 reviews)
I stayed at the InterContinental Houston for four nights and thoroughly enjoyed my stay. The staff was helpful and friendly. The room was beautiful and clean. Everyone in the lounge was helpful and friendly, and the food was good. The valet crew was terrific. Big shout-out to Abdalaziz, Liliana, ...

Reviewed on 11 Jan 2026

InterContinental Houston by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Central Houston

Historic area of Houston.

Greater Third Ward

If you're spending time in Greater Third Ward, check out sights like Carl Lewis International Track and Field Complex or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

Greater Third Ward
Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.

Midtown

Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Midtown Arts and Theater Center Houston and Continental Club are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.

Midtown
TMC

Museum District

Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Museum District
Taken from the parking garage.

#UrbanJungle

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Houston Central Business District
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

4/5(25 area reviews)

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

Downtown Houston
EyeEm Custom Shoots Q4 2018

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Montrose


South Central Houston Travel Guide