South Central Houston Travel Guide
Houston
Visit South Central Houston
Top hotels in South Central Houston
Hilton Houston Plaza/Medical Center
The property was wonderful, but the staff was Exemplary. I spent about 10-12 days here on different reservations and Seymour, at the front desk, was very helpful and attentive to all of my needs. Thank you Seymour!
Reviewed on 5 Jan 2026
Downtowner Inns - Houston Downtown
Room was nice, clean and close to midtown
Reviewed on 26 Dec 2025
Hotel Zaza Houston Museum District
Everything was nice except the pillows, if you can even call them that. Pillows should be trashed.
Reviewed on 2 Jan 2026
The Westin Houston Medical Center/Museum District
Staff was courteous. The beds were very comfortable. It was quiet considering it was New Year's Eve and we were able to get a good night's sleep.
Reviewed on 6 Jan 2026
InterContinental Houston by IHG
A
Reviewed on 1 Jan 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Only negative was at dinner the staff was overwhelmed by the amount of clientele
Reviewed on 1 Jan 2026
Other neighbourhoods around South Central Houston
Midtown
Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Midtown Arts and Theater Center Houston and Continental Club are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
