
Find hotels in Florence, SC from ฿2,197
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Florence
Pet friendly
Check prices for these dates
Our top choices for Florence hotels

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
8.6 out of 10, Excellent, (2,623 reviews)
The price is ฿2,170
฿2,430 total
includes taxes & fees
12 Apr - 13 Apr

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCFlorence
9.0 out of 10, Wonderful, (2,241 reviews)
The price is ฿3,074
฿3,443 total
includes taxes & fees
26 Apr - 27 Apr

Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHGLatta
9.6 out of 10, Exceptional, (570 reviews)
The price is ฿3,726
฿4,062 total
includes taxes & fees
3 May - 4 May

Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic CenterFlorence
8.4 out of 10, Very good, (60 reviews)
The price is ฿3,157
฿3,536 total
includes taxes & fees
6 May - 7 May

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center AreaFlorence
9.0 out of 10, Wonderful, (1,251 reviews)
The price is ฿3,383
฿3,789 total
includes taxes & fees
26 Apr - 27 Apr

Best Western Executive Inn
Best Western Executive InnLatta
8.2 out of 10, Very good, (980 reviews)
The price is ฿3,462
฿3,773 total
includes taxes & fees
15 Apr - 16 Apr

Tru by Hilton Florence I-95
Tru by Hilton Florence I-95Florence
8.4 out of 10, Very good, (1,006 reviews)
The price is ฿3,183
฿3,679 total
includes taxes & fees
27 Apr - 28 Apr

Hyatt Place Florence Downtown
Hyatt Place Florence DowntownFlorence
9.0 out of 10, Wonderful, (1,009 reviews)
The price is ฿3,988
฿4,466 total
includes taxes & fees
3 May - 4 May

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95Florence
9.0 out of 10, Wonderful, (890 reviews)
The price is ฿3,943
฿4,416 total
includes taxes & fees
6 May - 7 May

Days Inn by Wyndham Florence Near Civic Center
Days Inn by Wyndham Florence Near Civic CenterFlorence
7.0 out of 10, Good, (1,008 reviews)
The price is ฿2,150
฿2,408 total
includes taxes & fees
21 Apr - 22 Apr

Comfort Suites Florence I-95
Comfort Suites Florence I-95Florence
8.4 out of 10, Very good, (1,002 reviews)
The price is ฿3,157
฿3,795 total
includes taxes & fees
3 May - 4 May

The Mantissa Hotel
The Mantissa HotelHartsville
9.2 out of 10, Wonderful, (280 reviews)
The price is ฿2,942
฿3,295 total
includes taxes & fees
9 Apr - 10 Apr

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
8.6 out of 10, Excellent, (1,002 reviews)
The price is ฿4,086
฿4,576 total
includes taxes & fees
26 Apr - 27 Apr

Courtyard by Marriott Florence
Courtyard by Marriott FlorenceFlorence
7.8 out of 10, Good, (722 reviews)
The price is ฿3,171
฿3,551 total
includes taxes & fees
26 Apr - 27 Apr

Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SCFlorence
8.0 out of 10, Very good, (63 reviews)
The price is ฿2,912
฿3,390 total
includes taxes & fees
13 Apr - 14 Apr

Best Western Inn
Best Western InnFlorence
7.8 out of 10, Good, (1,001 reviews)
The price is ฿3,226
฿3,613 total
includes taxes & fees
21 Apr - 22 Apr

TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott FlorenceFlorence
9.0 out of 10, Wonderful, (798 reviews)
The price is ฿3,850
฿4,312 total
includes taxes & fees
14 Apr - 15 Apr

Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20Florence
9.0 out of 10, Wonderful, (616 reviews)
The price is ฿3,850
฿4,312 total
includes taxes & fees
22 Apr - 23 Apr

Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence CenterFlorence
9.0 out of 10, Wonderful, (870 reviews)
The price is ฿3,593
฿4,025 total
includes taxes & fees
3 May - 4 May

Aloft Florence
Aloft FlorenceFlorence
8.6 out of 10, Excellent, (306 reviews)
The price is ฿3,367
฿3,771 total
includes taxes & fees
26 Apr - 27 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Florence attractions
Florence and related destinations
Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Centre or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

Top Florence Hotel Reviews

Home2 Suites by Hilton Florence, SC
6/10 Okay
More cheap stays in Florence

Microtel Inn & Suites by Wyndham Florence
1912 Enterprise Dr Florence SC
The price is ฿1,961 per night from 27 Apr to 28 Apr
฿1,961
฿2,197 total
27 Apr - 28 Apr
includes taxes & fees
6.8/10 (1,003 reviews)














































































