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Check availability on Florence Family-Friendly Hotels

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Florence family-friendly hotels

Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2523)
"Great room and staff."
United States
LEE
The price is ฿1,955
฿2,190 total
includes taxes & fees
29 Dec - 30 Dec
Howard Johnson by Wyndham Florence
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (31)
"Friendly staff and clean environment "
United States
john
The price is ฿3,028
฿3,514 total
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Florence North I-95, SC
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (825)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is ฿3,555
฿3,982 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hampton Inn & Suites Florence-North-I-95
Exterior
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1005)
"Very good breakfast & convenient location"
United States
Diedre
The price is ฿3,414
฿3,824 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Exterior
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very good, (1672)
"Clean room & breakfast was good. Checkin staff was great, friendly and professional. "
United States
Cheryl
The price is ฿2,902
฿3,250 total
includes taxes & fees
30 Dec - 31 Dec
La Quinta Inn & Suites by Wyndham Florence
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1259)
"Room was spotless and the staff was friendly..."
United States
Randy
The price is ฿2,435
฿2,727 total
includes taxes & fees
28 Jan - 29 Jan 2026
Quality Inn & Suites Florence Civic Center
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (559)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is ฿3,403
฿3,811 total
includes taxes & fees
7 Jan - 8 Jan 2026
Fairfield Inn & Suites by Marriott Florence I-20
Indoor pool
Courtyard by Marriott Florence

Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (703)
"Very nice hotel. Clean, pleasant staff, and very well done room with comfortable bed."
United States
Kelly
The price is ฿3,007
฿3,368 total
includes taxes & fees
18 Jan - 19 Jan 2026
Courtyard by Marriott Florence
Exterior
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1002)
"Pool was clean good breakfast "
United States
Ann
The price is ฿3,184
฿3,690 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Florence I-95
Bar (on property)
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (606)
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is ฿4,046
฿4,532 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Florence, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

10/10 Excellent
"Great service besides kids hanging round doors it was alright experience."
Demetrius 1-night trip
Posted 9 days ago
Days Inn by Wyndham Florence Near Civic Center

Frequently asked questions

What's Florence like for family-friendly holidays?
The welcoming destination of Florence is a good choice if you've been considering a getaway with your children. The entertainment, excursions and museums are just a few things that make this an attractive holiday destination for families. Fly into Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the city centre.
What's the best family accommodation in Florence?
La Quinta Inn & Suites by Wyndham Florence is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other options for your child-friendly holiday include Howard Johnson by Wyndham Florence and Aloft Florence.
How many family hotels should I expect to find in Florence?
Expedia has 9 family-friendly hotels and other accommodation options in Florence.
When's the best time to book a family-friendly holiday in Florence?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.
What's there to see and do with your family in Florence?
While you are visiting Florence, you and the family may want to explore some interesting spots such as Dr. Eddie Floyd Tennis Center, Magnolia Mall and Drs Bruce and Lee Foundation Library. Make sure that you have lots of time for activities such as War Between the States Museum and Florence Motor Speedway.
What's the best way for us to get around Florence?
If you want to explore the larger area, hop aboard a train at Florence Station. Florence might not have very many public transport options, so consider renting a car to explore more.