Downtown South San Francisco Packages (Flight + Hotel)

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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

1 out of top 10 points of interest in this area

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿3,652 per night from 1 Sept to 2 Sept
฿3,652
฿4,280 total
1 Sept - 2 Sept
includes taxes & fees
8/10 Very Good! (2,012 reviews)
"I've stayed at this property a few times, as it fits my budget, is kinda close to SFSU, and has parking. The rooms are clean & comfortable, the showerheads are tall enough for a 6'3" person. Never used the pool. The breakfast is edible, but won't win any awards. There are a couple of nagging issues. ..."

Reviewed on 22 Aug 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿3,491 per night from 1 Sept to 2 Sept
฿3,491
฿5,447 total
1 Sept - 2 Sept
includes taxes & fees
8.8/10 Excellent! (6,706 reviews)
"Excellent location, easily walkable to all the places we wanted to visit. Felt safe and easy parking. We were concerned our car may have been over height, there is a 6ft limit but we got in fine. However you can also use the parking in the hotel opposite which has a greater height allowance. Staff ..."

Reviewed on 24 Aug 2025

Hotel Riu Plaza Fisherman's Wharf
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿5,230 per night from 28 Aug to 29 Aug
฿5,230
฿7,682 total
28 Aug - 29 Aug
includes taxes & fees
9.2/10 Wonderful! (1,816 reviews)
"This hotel is very very quiet. I did not hear the neighbors at all. The room was very large with a stunning view on the 17th floor. I stayed over the weekend when the prices were very reasonable, less than $200 a night. The price almost doubled during the week. I discovered this when my flight was ..."

Reviewed on 23 Aug 2025

Hyatt Regency San Francisco
See all 4,683 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco holiday package cost?
From just . Yes, you read that right. Our Downtown South San Francisco holiday packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream holiday to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Centre, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco holiday?
Travellers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organising an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco holiday package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Popular places to visit

Golden Gate Park featuring a garden and flowers

Golden Gate Park

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park
Pier 39 featuring street scenes, a city and signage

Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Golden Gate Bridge featuring a suspension bridge or treetop walkway, night scenes and general coastal views

Golden Gate Bridge

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge

Things to do

Golden Gate Bridge at night

San Francisco Night Tour

฿1,720
per adult
78% of travellers recommend
San Francisco Night Tour
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

฿4,512
per adult
92% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

฿1,233
per adult
90% of travellers recommend
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.