Downtown South San Francisco Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Union Square featuring a skyscraper and a city

Union Square

4/5(287 area reviews)

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Find hotels in Union Square

Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿3,322 per night from 2 Nov to 3 Nov
฿3,322
฿3,902 total
2 Nov - 3 Nov
includes taxes & fees
8/10 Very Good! (2,021 reviews)
"Just ok"

Reviewed on 6 Oct 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿4,292 per night from 10 Nov to 11 Nov
฿4,292
฿5,051 total
10 Nov - 11 Nov
includes taxes & fees
8.8/10 Excellent! (4,707 reviews)
"I enjoyed my stay — the hotel had a welcoming atmosphere and the amenities were nice. The room was spacious and the bed was comfortable. The only thing that stood out was that it wasn’t quite as clean as I expected (a bit of dust and a few missed spots). Other than that, it was a good experience, ..."

Reviewed on 20 Oct 2025

Holiday Inn Golden Gateway by IHG
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

3 out of 5
380 S Airport Boulevard, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is ฿3,117 per night from 7 Nov to 8 Nov
฿3,117
฿3,682 total
7 Nov - 8 Nov
includes taxes & fees
8.4/10 Very Good! (1,649 reviews)
"Shuttle was on time"

Reviewed on 21 Oct 2025

Best Western Plus Grosvenor Airport Hotel
See all 4,656 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco holiday package cost?
From just . Yes, you read that right. Our Downtown South San Francisco holiday packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream holiday to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Centre, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco holiday?
Travellers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organising an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco holiday package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Popular places to visit

Golden Gate Park featuring a garden and flowers

Golden Gate Park

4.5/5(323 reviews)

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park
Pier 39 featuring street scenes, a city and signage

Pier 39

4/5(364 reviews)

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Golden Gate Bridge featuring a suspension bridge or treetop walkway, night scenes and general coastal views

Golden Gate Bridge

4.5/5(362 reviews)

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

฿1,602
per adult
84% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

฿4,544
per adult
92% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

฿1,896
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.