Find hotels in Charleston, MO from ฿1,999
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Charleston
Pet friendly
Family friendly
Check prices for these dates
Our top choices for Charleston hotels

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (618 reviews)
The price is ฿1,948
฿2,162 total
includes taxes & fees
8 Feb - 9 Feb

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
The price is ฿1,902
฿2,111 total
includes taxes & fees
11 Jan - 12 Jan

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿2,829
฿3,253 total
includes taxes & fees
14 Jan - 15 Jan

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
The price is ฿2,823
฿3,185 total
includes taxes & fees
8 Feb - 9 Feb

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (487 reviews)
The price is ฿3,021
฿3,408 total
includes taxes & fees
5 Feb - 6 Feb


Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
The price is ฿2,196
฿2,499 total
includes taxes & fees
8 Feb - 9 Feb

Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
The price is ฿3,804
฿9,117 total
includes taxes & fees
25 Jan - 26 Jan

Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very good, (1,008 reviews)
The price is ฿2,111
฿2,406 total
includes taxes & fees
18 Jan - 19 Jan

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (728 reviews)
The price is ฿1,745
฿1,988 total
includes taxes & fees
11 Jan - 12 Jan

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (275 reviews)
The price is ฿2,237
฿2,483 total
includes taxes & fees
17 Jan - 18 Jan

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (445 reviews)
The price is ฿2,924
฿3,311 total
includes taxes & fees
25 Jan - 26 Jan

Pear Tree Inn Sikeston
Pear Tree Inn SikestonSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿2,358
฿2,710 total
includes taxes & fees
14 Jan - 15 Jan

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (460 reviews)
The price is ฿3,144
฿3,560 total
includes taxes & fees
25 Jan - 26 Jan

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (477 reviews)
The price is ฿3,804
฿4,311 total
includes taxes & fees
25 Jan - 26 Jan

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (148 reviews)
The price is ฿2,761
฿3,115 total
includes taxes & fees
25 Jan - 26 Jan

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ฿2,200
฿2,483 total
includes taxes & fees
14 Jan - 15 Jan

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very good, (284 reviews)
The price is ฿2,779
฿3,168 total
includes taxes & fees
14 Jan - 15 Jan

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿2,823
฿3,185 total
includes taxes & fees
8 Feb - 9 Feb

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,002 reviews)
The price is ฿1,978
฿2,254 total
includes taxes & fees
12 Jan - 13 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Charleston
Quaint Charleston is calling! Discover its opera, entertainment, dining and more.

Top Charleston Hotel Reviews

Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
More cheap stays in Charleston

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
The price is ฿1,978 per night from 12 Jan to 13 Jan
฿1,978
฿2,254 total
12 Jan - 13 Jan
includes taxes & fees
7.2/10 Good! (1,002 reviews)




































































