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Search Hotels Near Calle 50, Panama City

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9 Dec - 10 Dec
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10 Dec - 11 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Calle 50 hotels

Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (121)
"Great hotel fair price"
United States
Santiago
The price is ฿4,308
฿4,738 total
includes taxes & fees
13 Dec - 14 Dec
Hyatt Regency Panama City
Outdoor pool, pool umbrellas, pool loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco, 1 km from Calle 50
9.6 out of 10, Exceptional, (1104)
"Property and location was excellent. Staff is very accommodating and helpful. "
Canada
Helen
The price is ฿3,797
฿4,177 total
includes taxes & fees
24 Dec - 25 Dec
Ramada Plaza by Wyndham Panama Punta Pacifica
Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4641)
"Awesome great place to stay "
United States
Herbert
The price is ฿3,908
฿4,298 total
includes taxes & fees
10 Dec - 11 Dec
Hotel Riu Plaza Panama
Exterior
Yoo Apartamento

Yoo Apartamento

3.0 star property
Bella Vista, 1.3 km from Calle 50
9.6 out of 10, Exceptional, (10)
"the place was clean with an awesome and helpful staff. The views of the city from the balcony and the bedroom spectacular especially at night."
United States
edward
The price is ฿2,808
฿4,493 total
includes taxes & fees
23 Dec - 24 Dec
Yoo Apartamento
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1000)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is ฿5,858
฿6,444 total
includes taxes & fees
12 Dec - 13 Dec
Bristol Panama, a Registry Collection Hotel
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2137)
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
The price is ฿3,445
฿3,789 total
includes taxes & fees
2 Jan - 3 Jan 2026
Plaza Paitilla Inn Hotel
Lobby
The Executive Hotel

The Executive Hotel

3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1006)
"Clean room, friendly staff, great breakfast daily. I would always recommend this hotel to my friends and family. "
United States
Roxanne Timolyn Thomas
The Executive Hotel
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1587)
"Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever. "
United States
Lakshmin
The price is ฿1,595
฿1,755 total
includes taxes & fees
27 Dec - 28 Dec
Principe Hotel and Suites
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1016)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is ฿3,389
฿3,728 total
includes taxes & fees
13 Dec - 14 Dec
Novotel Panama City
Outdoor pool, free pool cabanas, pool loungers
Yoo Panama & Arts Tower

Yoo Panama & Arts Tower

3.0 star property
Bella Vista, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (46)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco, 0.4 km from Calle 50
8.8 out of 10, Excellent, (1000)
"Staff was very helpful. Great location."
United States
John
The price is ฿3,634
฿3,998 total
includes taxes & fees
3 Jan - 4 Jan 2026
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, pool loungers
Gran Evenia Panama

Gran Evenia Panama

4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (191)
"The staffing was pleasant and room clean "
United States
Okeicha
Gran Evenia Panama
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1005)
"Wonderful stay!"
United States
Martha
The price is ฿5,581
฿6,139 total
includes taxes & fees
14 Dec - 15 Dec
Las Americas Golden Tower Panama
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
El Cangrejo, 1.4 km from Calle 50
9.2 out of 10, Wonderful, (1007)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is ฿2,913
฿3,205 total
includes taxes & fees
16 Dec - 17 Dec
TRYP by Wyndham Panamá Centro
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
Obarrio, 0.6 km from Calle 50
8.8 out of 10, Excellent, (1001)
"Amazing amazing service"
United States
KFIR
The price is ฿5,074
฿5,581 total
includes taxes & fees
13 Dec - 14 Dec
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
Campo Alegre, 0.7 km from Calle 50
8.8 out of 10, Excellent, (1004)
"The staff members are amazing!!"
United States
Cherisse
The price is ฿2,744
฿3,194 total
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Panama Distrito Financiero by IHG
Exterior
Hotel Milan

Hotel Milan

3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (424)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is ฿1,276
฿1,404 total
includes taxes & fees
10 Dec - 11 Dec
Hotel Milan
Balcony
Nomada Container Hotel Panama City

Nomada Container Hotel Panama City

3.0 star property
Obarrio, 0.5 km from Calle 50
8.8 out of 10, Excellent, (162)
"I loved this place- great location, friendly staff, clean and comfy for a nice price. I've already booked my next stay!"
United States
Jodene
The price is ฿2,171
฿2,388 total
includes taxes & fees
10 Dec - 11 Dec
Nomada Container Hotel Panama City
Outdoor pool
MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (298)
"Second stay, very nice"
Canada
Xiaozhi
The price is ฿8,041
฿8,845 total
includes taxes & fees
11 Dec - 12 Dec
MARINN PLACE Financial District
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

4.0 star property
Punta Paitilla, 1 km from Calle 50
9.0 out of 10, Wonderful, (535)
"Amazing hotel amazing view service great location perfect "
United States
Melissa
The price is ฿5,126
฿5,639 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Calle 50 Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Always nice to stay and have experience the service of the company excels my expectation "
Dana 1-night trip
Posted 18 hours ago
Hotel Riu Plaza Panama

Hotels near other Calle 50 attractions

You can find Gucci at Luxury Avenue at Multiplaza Mall in Panama City. #LuxuryShopping #LifeatExpedia #PanamaCity
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

4.4/5 (1,590 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
See properties
Nice building, highlight on Panama's skyline.
Photo by My World
Open Photo by My World

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.
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Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 471 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Calle 50?
Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a short distance include Hotel Riu Plaza Panama and Las Americas Golden Tower Panama.
How many hotels can I expect to find near Calle 50?
Expedia has 471 hotels and other accommodation options within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle and Anita Villalaz Theater.
How can I get to Calle 50?
Nearby metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore farther outside of the area, you may want a car rental for your journey.

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