The Best Hotels Closest to Calle 50 in Panama City - 2026 Updated Prices

A cityscape with modern skyscrapers and lush green trees.

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Our top choices for Calle 50 hotels

A modern living room with a sectional sofa, a small ottoman, a flat-screen TV, and abstract art on the walls.

A dining area with a marble floor, a modern chandelier, and a vase with red flowers on the table.

A modern kitchen with a stainless steel refrigerator, granite countertop, and wooden cabinets.

A covered outdoor area with artificial grass, a seating arrangement, and a decorative chair.

1. Casa Bianca

Bella Vista, 1.8 km from Calle 50

Jose A

฿5,597

฿6,157 total

includes taxes & fees

19 Oct - 20 Oct

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

A modern interior with a central seating area, potted plants, and a staircase.

A spacious lobby with a curved ceiling, a central staircase, and a reception desk.

A modern building with a sign reading 'HYATT REGENCY.'

2. Hyatt Regency Panama City

Campo Alegre, 1 km from Calle 50

Mariah

฿6,286

฿6,915 total

includes taxes & fees

31 Oct - 1 Nov

A covered outdoor seating area with a view of a city skyline and water.

A hotel room with two beds, a desk, and a large window offering a city view.

A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.

3. Plaza Paitilla Inn Hotel

Punta Paitilla, 1.3 km from Calle 50

Milton

฿4,000

฿4,400 total

includes taxes & fees

26 Oct - 27 Oct

A modern lobby with a chandelier, seating area, reception desk, and a staircase.

A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

A lobby with a reception desk, seating area, and a bar.

A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

4. The Executive Hotel

Campo Alegre, 1.2 km from Calle 50

Sandra

฿2,982

฿3,280 total

includes taxes & fees

21 Oct - 22 Oct

A hotel named PRINCIPE with a modern facade and large glass windows.

A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

A hotel room with a TV mounted on the wall, a large mirror, and a red bedspread.

A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.

5. Principe Hotel and Suites

El Cangrejo, 0.9 km from Calle 50

Willis

฿1,988

฿2,186 total

includes taxes & fees

28 Oct - 29 Oct

A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

A hotel room with a bed and a view of a cityscape through sheer curtains.

A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.

A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

6. Novotel Panama City

El Cangrejo, 1.1 km from Calle 50

CARLOS

฿3,880

฿4,268 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.

A spacious lobby with a blue sofa set, a coffee table, and a green ottoman. There is a large window with a view of palm trees outside.

A lobby with seating areas, a reception desk, and a chandelier.

A hotel room with a bed, a desk, a chair, and a sofa.

7. Hotel Milan

El Cangrejo, 1.3 km from Calle 50

Arshak Andrew

฿1,345

฿1,479 total

includes taxes & fees

14 Oct - 15 Oct

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.

A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

8. Hotel Riu Plaza Panama

Campo Alegre, 0.7 km from Calle 50

Avanel

฿4,444

฿4,888 total

includes taxes & fees

21 Oct - 22 Oct

An outdoor patio area with tables and chairs, a pool, and a covered seating area.

A staircase with a red handrail leading to an upper floor.

A small, clean room with a white air conditioner, a white refrigerator, a flat-screen TV mounted on the wall, and a bed with a white mattress.

A hallway with a white wall featuring a motivational quote.

9. Hostal Familiar Carmencita - Hostel

Bella Vista, 1.1 km from Calle 50

Brooke

฿1,446

฿1,590 total

includes taxes & fees

8 Oct - 9 Oct

A rooftop pool with sun loungers and a city skyline in the background.

A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.

A bar area with a curved counter, multiple screens, and a patterned carpet.

A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

10. Waymore Hotel Spa & Casino

El Cangrejo, 1.4 km from Calle 50

kevin

฿3,000

฿5,149 total

includes taxes & fees

8 Oct - 9 Oct

A hotel room with a large bed, a desk, a chair, a painting, and a city view.

A modern office with two desks, each with a computer, keyboard, and mouse. There are four chairs, and a small plant is visible.

A spacious banquet hall with round tables and white chairs, large windows, and a central floral arrangement.

A TRYP PANAMA CENTRO reception area with a modern design, including a reception desk, seating area, and a large screen.

11. TRYP by Wyndham Panamá Centro

El Cangrejo, 1.4 km from Calle 50

Donna

฿2,720

฿2,992 total

includes taxes & fees

18 Oct - 19 Oct

A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

A modern bar area with multiple seating options and a view of the cityscape.

A hotel room with two beds, a sofa, a bench, a TV, and a view of buildings.

A modern conference room with a long table, colorful chairs, and large windows offering a city view.

12. Residence Inn by Marriott Panama City

Punta Paitilla, 1 km from Calle 50

david

฿6,320

฿6,952 total

includes taxes & fees

27 Oct - 28 Oct

A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

A spacious living area with modern furniture, a round coffee table, and a large window offering a view of the outdoors.

A modern hotel lobby with sofas, a coffee table, and a reception desk.

A bedroom with a large TV mounted on a marble wall, a bed, and a wooden cabinet.

13. La Résidence Panamá

Campo Alegre, 1 km from Calle 50

Mohamad

฿4,602

฿5,062 total

includes taxes & fees

13 Oct - 14 Oct

A rooftop pool with lounge chairs and a city skyline view.

A woman sitting on a bed in a hotel room with a city view.

A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

A person seated on a wicker chair with a view of a cityscape through large windows.

14. Hotel Dann Carlton Marinn Place Panama Financial District

Campo Alegre, 1.2 km from Calle 50

Eliana

฿2,464

฿3,634 total

includes taxes & fees

5 Nov - 6 Nov

15. San Francisco by Wynwood House

San Francisco, 1.2 km from Calle 50

Georg

฿3,821

฿5,045 total

includes taxes & fees

18 Oct - 19 Oct

A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

An indoor swimming pool with lounge chairs and a modern interior design.

A spacious lobby with a staircase, seating area, and a bar.

A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

16. Las Americas Golden Tower Panama

Punta Paitilla, 0.9 km from Calle 50

Armando

฿5,107

฿5,618 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with wooden tables and chairs, surrounded by potted plants and a yellow wall.

A garden pathway with various plants and a yellow brick path.

A dining area with wooden tables and chairs, a staircase, and a sofa.

A hotel room with two beds, a sofa, and a brick wall with artwork.

17. Panama House Bed & Breakfast

Bella Vista, 1 km from Calle 50

John

฿984

฿1,082 total

includes taxes & fees

12 Oct - 13 Oct

A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.

A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.

18. Courtyard by Marriott Panama Multiplaza Mall

San Francisco, 0.4 km from Calle 50

SHARROW

฿3,816

฿4,198 total

includes taxes & fees

31 Oct - 1 Nov

A rooftop pool with blue lounge chairs and a city skyline view.

A modern lounge area with white furniture, glass tables, and a city view.

A modern interior with a seating area, a wine rack, and a bar.

A modern building with a glass entrance, seating area, and a reception desk.

19. Best Western Plus Panama Zen Hotel

El Cangrejo, 1.1 km from Calle 50

Tashana Gittens

฿3,798

฿4,177 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel pool area with lounge chairs and a clear view of the ocean.

A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

A modern bar area with seating and a view of the city.

A modern interior with a spiral staircase, a large window, and a seating area.

20. Hilton Panama

Bella Vista, 1.3 km from Calle 50

Simon

฿8,372

฿9,210 total

includes taxes & fees

6 Nov - 7 Nov

View all properties

Compare popular hotels close to Calle 50

Property	Property class	Guest rating
Casa Bianca	9.8 Exceptional 8 reviews	View
Hyatt Regency Panama City	9.6 Exceptional 471 reviews	View
Plaza Paitilla Inn Hotel	9.4 Exceptional 2,235 reviews	View
The Executive Hotel	9.2 Wonderful 1,274 reviews	View
Principe Hotel and Suites	9.0 Wonderful 2,089 reviews	View

Top Calle 50 Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"Breakfast is excellent. Property is on the city center. Nice view"

Decapolis Hotel Panama City

10/10 Excellent

"Bueno"

Megapolis Hotel Panamá

10/10 Excellent

"Nice place, great pool area and great central location.."

Principe Hotel and Suites

8/10 Good

"The property was clean and the staff were very nice especially the gentleman clerk at the front desk . Always smiling and helpful."

Residence Inn by Marriott Panama City

10/10 Excellent

"Great place!"

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent

"Very nice hotel. The breakfast dinning room is beautiful, very big windows and so light. Our room was also very nice and the whole hotel looks new. Very well maintained."

Las Americas Golden Tower Panama

10/10 Excellent

"Muy buena ubicación, habitaciones limpias y espaciosas. Bar abierto hasta las 11pm"

Hotel Dann Carlton Marinn Place Panama Financial District

10/10 Excellent

"Excelente breakfast"

Holiday Inn Panama Distrito Financiero by IHG

8/10 Good

"Only problem was the pool was dirty. Breakfast buffet was excellent, staff was excellent"

Other attractions near Calle 50

A cityscape with a rainbow over buildings.

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

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A spiraling skyscraper against a clear blue sky.

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.

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A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

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Bingo 90

7.0/10 (12 reviews)

Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.

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Pacific Center

You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.

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National Shrine of the Heart of Mary

9.0/10 (17 reviews)

You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.

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Multicentro Panama

8.2/10 (274 reviews)

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

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Crown Casino

7.8/10 (412 reviews)

Why not roll the dice with a visit to Crown Casino during your visit to Panama City? Stroll along the seaside or visit the casinos in this vibrant area.

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Frequently asked questions

What's the area like around Calle 50?

Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 480 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Calle 50?

Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a short distance include Hotel Riu Plaza Panama and Megapolis Hotel Panamá.

How many hotels can I expect to find near Calle 50?

Expedia has 480 hotels and other accommodation options within a mile from Calle 50.

If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.

What can I see and do near Calle 50?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and National Bank House Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Anita Villalaz Theater and Amador Theater.

How can I get to Calle 50?

Nearby metro stations include Iglesia del Carmen Station and Vía Argentina Station. If you'd like to explore farther outside of the area, you may want a car rental for your journey.

Search Hotels Near Calle 50, Panama City

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Treat yourself

Be picky

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Our top choices for Calle 50 hotels

1. Casa Bianca

2. Hyatt Regency Panama City

3. Plaza Paitilla Inn Hotel

4. The Executive Hotel

5. Principe Hotel and Suites

6. Novotel Panama City

7. Hotel Milan

8. Hotel Riu Plaza Panama

9. Hostal Familiar Carmencita - Hostel

10. Waymore Hotel Spa & Casino

11. TRYP by Wyndham Panamá Centro

12. Residence Inn by Marriott Panama City

13. La Résidence Panamá

14. Hotel Dann Carlton Marinn Place Panama Financial District

15. San Francisco by Wynwood House

16. Las Americas Golden Tower Panama

17. Panama House Bed & Breakfast

18. Courtyard by Marriott Panama Multiplaza Mall

19. Best Western Plus Panama Zen Hotel

20. Hilton Panama

Compare popular hotels close to Calle 50

Top Calle 50 Hotel Reviews

Hotel Riu Plaza Panama

Decapolis Hotel Panama City

Megapolis Hotel Panamá

Principe Hotel and Suites

Residence Inn by Marriott Panama City

Courtyard by Marriott Panama Multiplaza Mall

Las Americas Golden Tower Panama

Hotel Dann Carlton Marinn Place Panama Financial District

Holiday Inn Panama Distrito Financiero by IHG

Other attractions near Calle 50

Multiplaza Pacific Mall

Soho City Center

Avenida Balboa

Bingo 90

Pacific Center

National Shrine of the Heart of Mary

Multicentro Panama

Crown Casino

Frequently asked questions