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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for Biscayne hotels

Restaurant

City Express by Marriott Yulee

City Express by Marriott Yulee
3.0 star property
19.2 km from Biscayne
8.2 out of 10, Very good, (729 reviews)
"Nice hotel very modern looking. Nice staff Great location"
United States
Liliane
The price is ฿3,096
฿3,313 total
includes taxes & fees
22 Jul - 23 Jul
City Express by Marriott Yulee
Lobby

Best Western Plus First Coast Inn & Suites

Best Western Plus First Coast Inn & Suites
2.5 star property
19.6 km from Biscayne
9.0 out of 10, Wonderful, (1,012 reviews)
"Food was great too"
United States
Joseph
The price is ฿3,880
฿4,152 total
includes taxes & fees
26 Jul - 27 Jul
Best Western Plus First Coast Inn & Suites
Exterior

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
Northside, 12.2 km from Biscayne
8.8 out of 10, Excellent, (1,001 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿2,938
฿3,335 total
includes taxes & fees
26 Jul - 27 Jul
Holiday Inn Express Jacksonville - Blount Island by IHG
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 26.2 km from Biscayne
9.2 out of 10, Wonderful, (1,115 reviews)
"Would stay again! Great area too!!"
United States
Alicia Ann
The price is ฿5,034
฿5,713 total
includes taxes & fees
21 Jul - 22 Jul
Hyatt Place Jacksonville / St. Johns Town Center
Lobby

DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport
4.0 star property
Northside, 4.5 km from Biscayne
8.4 out of 10, Very good, (1,735 reviews)
"Clean well maintained hotel minutes away from Food , Entertainment, and Shopping"
United States
Shyreak
The price is ฿3,249
฿3,688 total
includes taxes & fees
9 Aug - 10 Aug
DoubleTree by Hilton Hotel Jacksonville Airport
Indoor pool

Fairfield Inn & Suites Jacksonville West/Chaffee Point

Fairfield Inn & Suites Jacksonville West/Chaffee Point
3.0 star property
Northwest, 22.1 km from Biscayne
8.6 out of 10, Excellent, (711 reviews)
"Staff very helpful and professional"
United States
Donna
The price is ฿4,165
฿4,727 total
includes taxes & fees
18 Jul - 19 Jul
Fairfield Inn & Suites Jacksonville West/Chaffee Point
Restaurant

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
Northside, 7.2 km from Biscayne
9.0 out of 10, Wonderful, (537 reviews)
"Staff was nice and rooms were clean"
United States
teresia
The price is ฿2,712
฿3,078 total
includes taxes & fees
2 Aug - 3 Aug
Extended Stay America Premier Suites - Jacksonville - Airport
Lobby

Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station

Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
2.5 star property
Westside, 28.2 km from Biscayne
9.4 out of 10, Exceptional, (1,149 reviews)
"Breakfast was really good and the pool was great."
United States
Zachary
The price is ฿3,586
฿4,070 total
includes taxes & fees
10 Aug - 11 Aug
Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
Reception

Hampton Inn Jacksonville East Regency Square

Hampton Inn Jacksonville East Regency Square
2.5 star property
Arlington, 18.5 km from Biscayne
8.8 out of 10, Excellent, (1,000 reviews)
"Very nice stay"
United States
Anthony
The price is ฿2,976
฿3,377 total
includes taxes & fees
22 Jul - 23 Jul
Hampton Inn Jacksonville East Regency Square
Double Room, 2 Queen Beds, Non Smoking | In-room dining

San Marco Inn East

San Marco Inn East
3.0 star property
18.5 km from Biscayne
8.6 out of 10, Excellent, (1,445 reviews)
"Helpful staff"
United States
Carlos
The price is ฿2,291
฿2,600 total
includes taxes & fees
19 Jul - 20 Jul
San Marco Inn East
Exterior

Microtel Inn & Suites by Wyndham Jacksonville Airport

Microtel Inn & Suites by Wyndham Jacksonville Airport
2.5 star property
Northside, 4.3 km from Biscayne
7.6 out of 10, Good, (1,201 reviews)
"Great stay"
United States
Sean
The price is ฿2,594
฿2,944 total
includes taxes & fees
22 Jul - 23 Jul
Microtel Inn & Suites by Wyndham Jacksonville Airport
Exterior

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 14.2 km from Biscayne
9.0 out of 10, Wonderful, (1,714 reviews)
"Staff was excellent!!"
United States
Sabrina
The price is ฿6,028
฿6,910 total
includes taxes & fees
13 Aug - 14 Aug
Hyatt Regency Jacksonville
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
30.5 km from Biscayne
9.0 out of 10, Wonderful, (1,008 reviews)
"Breakfast was a hit and the pool is the best hotel pool we've seen in a long time!!"
United States
Patsy
The price is ฿3,542
฿4,021 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Front of property – evening/night

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
Northside, 4.8 km from Biscayne
9.0 out of 10, Wonderful, (2,537 reviews)
"Excellent place to stay. Close to Jaxport."
United States
Randall
The price is ฿3,368
฿3,822 total
includes taxes & fees
10 Aug - 11 Aug
Hyatt Place Jacksonville Airport
41-inch Smart TV with cable channels

Weekly Inn

Weekly Inn
2.0 star property
Arlington, 17.5 km from Biscayne
7.6 out of 10, Good, (1,364 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,808
฿2,052 total
includes taxes & fees
15 Jul - 16 Jul
Weekly Inn
Lobby

B&B HOTEL Jacksonville Airport – Newly Renovated!

B&B HOTEL Jacksonville Airport – Newly Renovated!
3.0 star property
Northside, 5 km from Biscayne
9.6 out of 10, Exceptional, (54 reviews)
"Beautiful room very friendly staff"
United States
John
The price is ฿3,056
฿3,469 total
includes taxes & fees
19 Jul - 20 Jul
B&B HOTEL Jacksonville Airport – Newly Renovated!
Lobby

Best Western Plus Jacksonville West

Best Western Plus Jacksonville West
2.5 star property
Northwest, 21.9 km from Biscayne
8.0 out of 10, Very good, (798 reviews)
"Great stay. Clean room."
United States
Betty
The price is ฿3,569
฿4,051 total
includes taxes & fees
18 Jul - 19 Jul
Best Western Plus Jacksonville West
Exterior

Tru by Hilton Jacksonville West I 295

Tru by Hilton Jacksonville West I 295
3.0 star property
Northwest, 11.1 km from Biscayne
9.0 out of 10, Wonderful, (277 reviews)
"The pool was amazing"
United States
Tinisha
The price is ฿3,542
฿4,021 total
includes taxes & fees
26 Jul - 27 Jul
Tru by Hilton Jacksonville West I 295
Outdoor pool, pool umbrellas, pool loungers

Hampton Inn Suites Jacksonville Airport

Hampton Inn Suites Jacksonville Airport
2.5 star property
Northside, 4.7 km from Biscayne
8.6 out of 10, Excellent, (1,013 reviews)
"Hotel is very convenient to the airport. Breakfast was great and they even had to go breakfast for travelers."
United States
Marjorie
The price is ฿2,856
฿3,241 total
includes taxes & fees
26 Jul - 27 Jul
Hampton Inn Suites Jacksonville Airport
Premium bedding, desk, blackout curtains, iron/ironing board

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
30.2 km from Biscayne
7.6 out of 10, Good, (547 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,432
฿2,760 total
includes taxes & fees
27 Jul - 28 Jul
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Biscayne

Find the best Biscayne areas for the activities you enjoy most.
A coastal cityscape at dusk with a prominent clock tower, waterfront, and historic buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

A city skyline at night with illuminated buildings and a bridge reflecting on the water.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A sunset over a beach with fallen trees and a distant shoreline.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Biscayne Hotel Reviews

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

8/10 Good
"I expected a much better experience based on this hotel’s reputation and rating. The lobby is attractive and makes a good first impression, but unfortunately the room did not meet the same standard. The biggest disappointment was the cleanliness. We found dirty towels and dirty tables when we arrived, and instead of calling housekeeping, we ended up cleaning and disinfecting the room ourselves so we could feel comfortable staying there. The beds were also much firmer than expected, making it difficult to get a good night’s sleep. In addition, the room felt smaller than expected. I’ve stayed at Hyatt Place properties with noticeably larger and more comfortable rooms. Overall, this hotel did not feel like a true 4.5-star property. While the location is convenient and the lobby is nice, the cleanliness and room experience fell short of expectations. I hope management pays closer attention to housekeeping, as that would make a significant difference."
Jose 1-night trip
Posted 5 hours ago
Hilton Jacksonville At Mayo Clinic

Frequently asked questions

What is Biscayne like?
Travellers to the Biscayne neighbourhood in Jacksonville will be sure to enjoy their stay.
How many hotels are there in Biscayne?
When you want to find places to stay in Jacksonville, start by booking one of Expedia's 5 hotels and other accommodation options in Biscayne.
If I need to cancel my hotel reservation in Biscayne, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Biscayne.
What can I see and do in this Jacksonville neighbourhood?
Catherine Street Fire Station #3, Abyssinia Missionary Baptist Church and Anheuser-Busch Brewery are just a few of the places to visit in and around Biscayne. When you're sightseeing around the area, Oceanway Community Center and River City Market Place are a couple of other sights to visit.

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