Affton Holiday Rentals, St. Louis: Private House Rentals

A city skyline with a prominent arch bridge over a river, featuring several high-rise buildings and boats on the water.

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Our top choices for Affton hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown

Jennifer

฿4,627

฿5,456 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

2. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

St. Louis

Thomas

฿3,873

฿4,453 total

includes taxes & fees

25 Oct - 26 Oct

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A hotel indoor pool area with a hot tub, seating, and a view of the outdoors.

A modern hotel with a covered entrance, brick facade, and a parking area.

A modern hotel lobby with a high ceiling, multiple hanging pendant lights, a reception desk with a Missouri US 66 sign, and large windows allowing natural light.

3. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Dashaun

฿3,150

฿3,638 total

includes taxes & fees

28 Sept - 29 Sept

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a mix of natural and artificial lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

4. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Crystal

฿3,462

฿4,024 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

An outdoor patio with round tables and chairs, umbrellas, and a brick building in the background.

A gym with treadmills and exercise equipment.

A reception area with a wooden reception desk, a clock, a television mounted on the wall, and a refrigerator stocked with beverages.

5. SpringHill Suites St. Louis Brentwood

Brentwood

Cheryl

฿3,852

฿4,545 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with multiple seating areas, a central coffee table, and artwork on the walls.

A gym with treadmills, an elliptical, and dumbbells on shelves.

A hotel with multiple floors, a prominent 'Best Western' sign, and a parking area with several cars.

A hotel room with two beds, a nightstand with a lamp, a painting on the wall, and a window with curtains.

6. Best Western St. Louis-Kirkwood Route 66

Kirkwood

Mildred

฿3,217

฿3,763 total

includes taxes & fees

6 Oct - 7 Oct

A modern lobby with a stone fireplace, blue sofas, and potted plants.

A modern building with a stone facade, large windows, and a covered entrance area.

A modern kitchen with a coffee machine, microwave, and refrigerator. There is a dining area with tables and chairs.

A hotel room with two beds, a desk, and a window with a city view.

7. Comfort Suites St. Louis - Sunset Hills

St. Louis

John

฿3,945

฿4,585 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a sofa set, a coffee table, and a TV mounted on the wall.

A reception area with a wooden wall and a large decorative piece. There are two reception counters and a sign on the wall.

A Marriott Fairfield hotel with a covered entrance, stone facade, and a clear sky.

A hotel room with two beds, a flat-screen TV mounted on the wall, a minibar, and a wooden wardrobe.

8. Fairfield Inn & Suites by Marriott St. Louis South

St. Louis

Terry

฿3,886

฿4,468 total

includes taxes & fees

11 Oct - 12 Oct

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.

A large hotel with a prominent "RIVER CITY" sign.

9. River City Casino & Hotel

St. Louis

Ashley

฿3,244

฿4,262 total

includes taxes & fees

27 Oct - 28 Oct

A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

A modern lobby with a grey sofa, two armchairs, a round table, and a chandelier. There are two posters on the wall and a reception desk in the background.

A gym with various exercise equipment, large windows, and a skylight.

A restaurant interior with wooden panel walls, hanging light fixtures, and a chalkboard menu. Tables and chairs are arranged for dining.

10. Holiday Inn St Louis SW - Route 66 by IHG

St. Louis

Arnaud

฿3,840

฿4,568 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

A gym with treadmills, exercise bikes, and a mirror.

A snack display area with various packaged snacks and a refrigerated section.

11. Hampton Inn & Suites St. Louis/South I-55

St. Louis

Shannon

฿3,532

฿4,061 total

includes taxes & fees

18 Oct - 19 Oct

A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

A hotel room with two beds, a desk, and a window with a view of trees.

An outdoor patio area with a fire pit, black metal chairs, and a blue umbrella.

A gym with treadmills, elliptical machines, and a mirrored wall.

12. Best Western Plus Fenton

Fenton

Evelyn

฿3,236

฿3,736 total

includes taxes & fees

29 Sept - 30 Sept

A lobby with a reception desk, seating area, and a bicycle in the background.

A conference room with a long table, chairs, water bottles, and a projector screen.

13. Drury Inn & Suites St. Louis Forest Park

Clifton Heights

Robert

฿4,974

฿5,816 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a staircase, dining area, and reception desk.

An indoor swimming pool with a tiled floor, a pool ladder, and a few chairs and tables around the pool area.

A coffee station with two coffee machines, a shelf with coffee cups, and a storage area with boxes and a thermos.

A hotel room with a large bed, a separate bathroom with a bathtub, a flat-screen TV, and a framed picture on the wall.

14. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton

Charles

฿3,172

฿3,663 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

15. Courtyard by Marriott St. Louis Brentwood

Richmond Heights

Aaron

฿3,803

฿4,644 total

includes taxes & fees

4 Oct - 5 Oct

A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

A large indoor pool with clear glass walls, a tiled edge, and a seating area with chairs and tables.

A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

16. Best Western St. Louis Inn

St. Louis

Alexus

฿2,532

฿2,912 total

includes taxes & fees

27 Sept - 28 Sept

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

17. Wingate by Wyndham St. Louis Airport

St. Ann

Tessa

฿3,122

฿3,676 total

includes taxes & fees

27 Sept - 28 Sept

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

A lobby with a reception desk, seating area, and large windows.

A modern building with a prominent entrance, large windows, and a covered parking area.

A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.

18. Pear Tree Inn St. Louis Arnold

Arnold

Lynda

฿3,005

฿3,473 total

includes taxes & fees

5 Oct - 6 Oct

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A living room with a brown leather sofa, a small table, and a chair. There is a window with curtains, a lamp, and a framed picture on the wall.

A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.

A hotel room with two beds, a desk, a chair, and a television.

19. Clayton Plaza Hotel & Extended Stay

Clayton

Sivakumar

฿3,153

฿3,681 total

includes taxes & fees

11 Oct - 12 Oct

A rooftop terrace with wicker furniture, offering a city view.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A lobby with seating areas, a chandelier, and a large pillar.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

20. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Salvatore

฿4,507

฿5,270 total

includes taxes & fees

25 Oct - 26 Oct

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Learn more about Affton

This small St. Louis suburb offers family fun at Affton Plaza Bowl and Grant's Farm with its Budweiser Clydesdales. Grab a slice at local favourite Pirrone's Pizzeria, then catch a Cardinals game or visit the Gateway Arch in nearby St. Louis.

See all hotels in Affton

Top Affton Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"I had a wonderful stay. Staff is fantastic. Great free breakfast. Secure parking. I will be staying here again on my next trip to St. Louis."

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"Overall I had a positive experience because of the event occuring duriong the time of my visit. The staff was friendly, helpful and professtional. I was grateful after a long travel trip to be greeted by kind staff - reception, valet, security. Each very different and very helpful. Breakfast was fine both dayss. The surrounding area is was not desirable. We felt safe because our stay was during the Beatification of Archbishop Fulton Sheen so there was alot of traffic, cars and people everywhere. The condition of the front desk, lobby and rooms are very good. Disappointing was the hallway, up near the rooms. Unfortunately, the location is the only thing that would kept me from rebooking."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Great breakfast and happy hour. I would highly recommend."

Forest Park Hotel by MDR

8/10 Good

"Comfortable bed and room. Friendly staff. Convenient location."

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Will definitely book again through them. Great price for the time I stayed and close to everything"

Courtyard by Marriott St. Louis Downtown/Convention Center

8/10 Good

"Very nice large rooms. Very clean. A bit of traffic noise, but overall, a nice place to stay."

21C Museum Hotel St Louis

10/10 Excellent

"A bit off the beating path, but well worth the walk or ride there. Unfortunately I was only there for a day, so missed out on many of the amenities. But will definitely book here again and take advantage of all they have to offer. P.S. The room are well kept, roomy, and comfortable."

Live by Loews - St.Louis

10/10 Excellent

"Amazing. Such a great atmosphere!"

More cheap stays in Affton

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

฿2,532

฿2,912 total

27 Sept - 28 Sept

includes taxes & fees

8.4/10 Very good! (1,160 reviews)

Comfort Suites St Charles - St Louis

1400 S 5th St St. Charles MO

฿2,914

฿3,349 total

18 Oct - 19 Oct

includes taxes & fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

฿3,012

฿3,546 total

4 Oct - 5 Oct

includes taxes & fees

9.2/10 Wonderful! (3,261 reviews)

The West End

4215 Lindell Blvd St. Louis MO

฿2,641

฿3,756 total

27 Sept - 28 Sept

includes taxes & fees

8.6/10 Excellent! (654 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

฿3,258

฿3,809 total

6 Oct - 7 Oct

includes taxes & fees

7.8/10 Good! (989 reviews)

The Knight Center at Washington University

Throop Drive and Snow Way St. Louis MO

฿5,647

฿6,494 total

27 Sept - 28 Sept

includes taxes & fees

9.4/10 Exceptional! (689 reviews)

Frequently asked questions

What's the best place to stay in Affton?

Located 6.8 mi (10.9 km) from the heart of Affton, Clayton Plaza Hotel & Extended Stay is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are Hyatt Regency St. Louis at The Arch and Pear Tree Inn St. Louis Airport. See all available top hotels, or vacation rentals in Affton.

If I need to cancel my hotel reservation in Affton, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Affton.

How is it staying in Affton?

Visitors can enjoy all that Affton has to offer, including the restaurants, shopping and sporting events. Around the area, top sights include St. Louis Zoo, St. Louis Union Station and Enterprise Center. There are 1957 hotels and other accommodation options in the surrounding area. Find out more about Affton.

What are the top places to visit in Affton?

St. Louis Zoo, St. Louis Union Station and Enterprise Center are some of the notable places to visit in the surrounding area. You'll also find Ulysses S. Grant National Historic Site and Grant's Farm in the area. Take a look at what more there is to see and do in Expedia's Affton guide.

What's the weather like in Affton?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Affton is 1350 mm.

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Book Hotels in Affton on Expedia.com

Find hotels in Affton, MO from ฿2,912

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Be picky

Go beyond your typical stay in Affton

Check prices for these dates

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Our top choices for Affton hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

3. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

4. La Quinta Inn & Suites by Wyndham St Louis Route 66

5. SpringHill Suites St. Louis Brentwood

6. Best Western St. Louis-Kirkwood Route 66

7. Comfort Suites St. Louis - Sunset Hills

8. Fairfield Inn & Suites by Marriott St. Louis South

9. River City Casino & Hotel

10. Holiday Inn St Louis SW - Route 66 by IHG

11. Hampton Inn & Suites St. Louis/South I-55

12. Best Western Plus Fenton

13. Drury Inn & Suites St. Louis Forest Park

14. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

15. Courtyard by Marriott St. Louis Brentwood

16. Best Western St. Louis Inn

17. Wingate by Wyndham St. Louis Airport

18. Pear Tree Inn St. Louis Arnold

19. Clayton Plaza Hotel & Extended Stay

20. Drury Plaza Hotel St. Louis at the Arch

Learn more about Affton

Top Affton Hotel Reviews

Pear Tree Inn St. Louis Airport

Home2 Suites by Hilton St. Louis Downtown

Drury Plaza Hotel St. Louis Union Station

Forest Park Hotel by MDR

Renaissance St. Louis Airport Hotel

Courtyard by Marriott St. Louis Downtown/Convention Center

21C Museum Hotel St Louis

Live by Loews - St.Louis

More cheap stays in Affton

Best Western St. Louis Inn

Comfort Suites St Charles - St Louis

Pear Tree Inn St. Louis Airport

The West End

Tru By Hilton St. Louis Downtown

The Knight Center at Washington University

Frequently asked questions

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