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Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Travelers start their day with a hearty breakfast buffet at this convenient hotel, perfectly positioned for exploring the attractions of St. Louis

Choose dates to view prices

Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning
The current price is ฿3,815
฿4,387 total
includes taxes & fees
9 Aug - 10 Aug

Room options

Available filters for rooms
Showing 10 of 10 rooms

1 King Bed Nonsmoking

  • Sleeps 2
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.8 out of 10
Exceptional
(41 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.6 out of 10
Exceptional
(15 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Two Queen Beds, Non-Smoking, Accessible

A hotel room with a bed, desk, chair, television, and a minibar.

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(28 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for One King Bed, Non-Smoking, Accessible

A hotel room with a large bed, two bedside lamps, a nightstand with a phone, and a door to another room.

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(22 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Studio, Accessible, Non Smoking

A hotel room with a bed, a desk with a telephone, a chair, a sofa, a lamp, and a painting on the wall.

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

2 Queen Beds Nonsmoking

  • Sleeps 4
  • Free Wi-Fi

View all photos for 2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.

2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

  • Sleeps 4
  • Free Wi-Fi

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About the area

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. Grant's Farm and Swing-A-Round Fun Town are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
    Busch Stadium
    16 min drive - 27.9 km
  • The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.
    Gateway Arch
    17 min drive - 28.6 km
  • A historic building with a clock tower and red-roofed structures.
    St. Louis Union Station
    18 min drive - 27.9 km
  • A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.
    Forest Park
    20 min drive - 32.4 km
  • A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
    St. Louis Zoo
    23 min drive - 35.7 km

Getting around

  • Kirkwood Station
    14 min drive
  • Lambert-St. Louis International Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Subway
    3 min drive
  • Hardee's / Red Burrito
    10 min walk
  • Popeyes Louisiana Kitchen
    3 min walk

About this property

Hampton Inn & Suites St. Louis/South I-55

  • Hotel near Mississippi River
  • At Hampton Inn & Suites St. Louis/South I-55, you can look forward to a free breakfast buffet, a corner/local shop and dry cleaning/laundry services. Free in-room WiFi is available to all guests, along with a fireplace in reception and a gym.
  • Additional perks include:
    • An indoor pool
    • Free self-parking
    • Express check-in, laundry services and a banquet hall
    • A vending machine, free newspapers and coffee/tea in reception
    • Guest reviews speak highly of the breakfast and helpful staff
  • Room features
  • All 92 rooms include comforts such as air conditioning, as well as perks such as free WiFi and safes. Guest reviews speak positively of the cleanliness rooms at the property.
  • More conveniences in all rooms include:
    • Bathrooms with free toiletries and hairdryers
    • 37-inch LCD TVs with cable channels
    • Wardrobes/cupboards, fridges and microwaves

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business centre
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay films

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; check-in end time: midnight
Contactless check-in and check-out are available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Free cots are available on request at the property

Payment types at the property

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM to 10 PM.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of 9 Jul 2026, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on 9 Aug 2026 start from ฿3,815, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at Hampton Inn & Suites St. Louis/South I-55?

Self-parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Checkout is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 miles (5 km) of St Anthony's and Suson Park. Meramec River and Mercy Hospital South are also within 6 miles (10 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.6

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 816 out of 1002 reviews
Rating 8 - Good. 134 out of 1002 reviews
Rating 6 - Okay. 27 out of 1002 reviews
Rating 4 - Poor. 5 out of 1002 reviews
Rating 2 - Terrible. 20 out of 1002 reviews

Reviews

Verified

10/10 Excellent

Shawn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing hotel and staff
Stayed 8 nights in May 2026
Verified

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly, breakfast was delicious. I really enjoyed my stay
Stayed 1 night in Apr 2026
Verified

8/10 Good

Glenn R

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We stayed one night on our way back from Tulsa OK to Indianapolis. We were traveling with a small dog and needed space to walk her. We drove to area restaurants and stores and found them easily accessible without using the Interstate. The hotel was quiet and well kept, and the staff took care of our rather minor needs.
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Kim

Liked: Cleanliness, staff & service, property conditions & facilities
Parking felt safe , nice staff
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

winnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Arlene

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I had a great stay. Clean rooms and friendly staff
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My cousins and I were in town to see the Chicago Cubs play the St Louis Cardinals. This Hampton Inn & Suites was the perfect place to stay for the night. It is about a 20-minute Uber ride to the park but worked really well for us. It was very clean. The room was clean. The lobby was clean. The breakfast in the morning was very good and quite delicious. The lady who worked at breakfast, I did not catch her name, was so kind and sweet. I always look for clean hotels and this one definitely was great!
Stayed 1 night in May 2026
Verified

10/10 Excellent

mary

Liked: Cleanliness, staff & service, property conditions & facilities
Room was clean and comfortable Staff professional friendly and helpful Breakfast was great! Several choices.
Stayed 5 nights in Apr 2026
Verified

10/10 Excellent

Alison

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The front desk attendant was very helpful and welcoming. I was impressed wit the cleanliness of our room and the hot breakfast options. Would definitely stay there again!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff and room was GREAT!!! Parking was great!! Room was clean and well stocked. Breakfast was good as always. Nice comfortable environment that makes you feel home away from home. We will be returning.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Deloris

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was clean. Staff was courteous. The breakfast was average for 3 star hotel.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Phyllis

Liked: Cleanliness, staff & service, amenities
Nice clean room spacious
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Josi

Liked: Cleanliness, staff & service, amenities
Fast check in. Nice staff. Clean and quiet room!!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Miliska

Liked: Cleanliness, staff & service, amenities
The room was clean, modern, and pleasant. Staff members were welcoming, respectful, positive, and helpful.
Stayed 1 night in Jan 2026
Verified

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Manivannan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Parking is Safe, Cleanliness is Good. Hospitality is Appreciable.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025