A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

5 Stars Hotels in Panama City

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Check availability on Panama City 5 Star Hotels

Tonight
25 Aug - 26 Aug
Tomorrow
26 Aug - 27 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Our top choices for Panama City 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Lori
฿4,497
฿4,946 total
includes taxes & fees
16 Sept - 17 Sept
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
฿8,698
฿9,568 total
includes taxes & fees
30 Aug - 31 Aug
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Josh
฿11,189
฿12,307 total
includes taxes & fees
8 Sept - 9 Sept
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Tad Olivet Ottinger Welcome
฿4,149
฿4,564 total
includes taxes & fees
3 Sept - 4 Sept
Renaissance Panama City Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A modern interior with a central seating area, potted plants, and a staircase.

5. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Deanna
฿7,155
฿7,870 total
includes taxes & fees
3 Sept - 4 Sept
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carlos
฿8,783
฿9,661 total
includes taxes & fees
8 Sept - 9 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A high-rise building with a rooftop pool area, surrounded by other buildings.

7. W Panama

W Panama
Bella Vista
United States
Anna Lee
฿8,509
฿9,360 total
includes taxes & fees
19 Sept - 20 Sept
W Panama
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.

8. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Benjamin A
฿8,611
฿9,472 total
includes taxes & fees
12 Sept - 13 Sept
JW Marriott Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

9. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Robert
฿6,448
฿7,093 total
includes taxes & fees
25 Sept - 26 Sept
The Westin Playa Bonita Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A modern bar area with seating and a view of the city.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.

10. Hilton Panama

Hilton Panama
Bella Vista
United States
William
฿7,742
฿8,516 total
includes taxes & fees
18 Sept - 19 Sept
Hilton Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A person performing a yoga pose in a living room with a large window and a sofa.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Rafael
฿7,331
฿8,065 total
includes taxes & fees
6 Sept - 7 Sept
Bristol Panama, a Registry Collection Hotel

12. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
฿7,781
฿8,559 total
includes taxes & fees
25 Sept - 26 Sept
Megapolis Hotel Panamá
A rooftop pool with lounge chairs and a city skyline in the background.

13. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
฿3,576
฿3,934 total
includes taxes & fees
24 Sept - 25 Sept
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
฿4,116
฿4,744 total
22 Sept - 23 Sept
includes taxes & fees
8.6/10 Excellent! (2,716 reviews)
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
฿5,992
฿6,591 total
23 Sept - 24 Sept
includes taxes & fees
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Calle Augusto Samuel Boyd y Calle Eusebi Panama City
฿2,793
฿5,588 total
1 Sept - 2 Sept
includes taxes & fees
9/10 Wonderful! (1,094 reviews)
Waymore Hotel Spa & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Siempre bueno"
Felix Lazaro 4-night trip
Posted 2 hours ago
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

10/10 Excellent
"Dede el ingress estuvimos super bien recibidos hasta el check in y en lahabitacion super bien el de say unto muy recommendable y gran atencion"
Gaudy 1-night trip
Posted 14 hours ago
Waldorf Astoria Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"I absolutely love Hyatt, all their hotels match the vibe and energy of the country they're in and this location was no different! The hotel was beautifully decorated and peaceful. The coffee at Amado was great, I started my morning there each day. The drinks at Rulfo were also wonderful. The staff were kind and attentive, they provided umbrellas for us to use one afternoon when it was pouring rain. Room service also came quickly when we ordered. The housekeeping staff also did a great job with refreshing the rooms each day. Another highlight that I can't forget to mention is the gym, wow! The gym was two levels, complete with a sauna, a great assortment of weight lifting machines and equipment and Pelatons - honestly the best chain hotel gym I have ever seen. Overall this hotel comes highly recommended."
Aliyah 4-night trip
Posted 1 day ago
Hyatt Regency Panama City
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"Great hotel"
Carlos 2-night trip
Posted 2 days ago
Renaissance Panama City Hotel

Frequently asked questions

What are the best 5-star hotels in Panama City?
According to Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway.
  • Search for the lowest price per night from ฿4,744
What makes a hotel 5 stars in Panama City?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night.