The Best Hotels Closest to University of Chicago Medicine in Chicago - 2026 Updated Prices

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Our top choices for University of Chicago Medicine hotels

A modern hotel room with large windows, a sofa, chairs, a dining table, and a coffee table.

A spacious living area with a modern chandelier, comfortable seating, and a fireplace.

An outdoor seating area with sofas, chairs, and tables, surrounded by trees and string lights.

A bar area with a marble countertop, multiple shelves of bottles, and a large TV screen. There are several bar stools and a round table with a vase of flowers.

1. Sophy Hyde Park

Hyde Park, 1.6 km from University of Chicago Medicine

amy

฿9,063

฿11,628 total

includes taxes & fees

31 Oct - 1 Nov

A row of parked cars along a tree-lined street with multi-story buildings in the background.

A hotel room with a large bed, a desk, a chair, a nightstand, a lamp, and a mirror.

2. Chicago Lake Shore Hotel

2.5 km from University of Chicago Medicine

Princets

฿4,552

฿5,343 total

includes taxes & fees

1 Nov - 2 Nov

A room with large windows, a wooden floor, and a built-in air conditioning unit.

A hotel room with a large bed, a wooden headboard, a patterned bedspread, and a view through an open door to another room.

3. Best Motel By OYO Chicago I-90

1.7 km from University of Chicago Medicine

Saul

฿2,760

฿3,240 total

includes taxes & fees

21 Oct - 22 Oct

A modern indoor pool area with lounge chairs, a wooden table, and large windows.

A modern hotel with multiple floors, a covered entrance, and a parking lot.

A modern hotel room with a large bed, a desk, a chair, a TV, and a sliding door leading to a shower area.

A hotel reception area with a counter displaying pastries and coffee, a coffee machine, and a golden clock.

4. Hampton Inn & Suites Chicago Medical District UIC

11.2 km from University of Chicago Medicine

Bobby

฿5,077

฿6,037 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, a desk, a chair, a TV, and a colorful rug.

A coffee station with two espresso machines, a coffee grinder, and various coffee-related items.

A hotel reception desk with a modern design, including a digital display and a sign indicating it is a non-smoking property.

A Holiday Inn Express & Suites hotel with a modern facade, multiple parking spaces, and a well-lit entrance.

5. Holiday Inn Express Hotel & Suites Chicago-Midway Airport by IHG

11.6 km from University of Chicago Medicine

Roberto

฿4,850

฿5,698 total

includes taxes & fees

1 Nov - 2 Nov

A cityscape with high-rise buildings, a marina, and a waterfront.

A spacious indoor area with multiple tables and chairs, large windows, and a bar area.

A high-rise hotel with a modern design, featuring a prominent 'HYATT' sign, multiple floors, and a well-lit facade.

An outdoor seating area with fire pits, cushioned seating, and a glass building facade.

6. Hyatt Regency McCormick Place Chicago

Near South Side, 7.1 km from University of Chicago Medicine

Tony

฿9,363

฿12,117 total

includes taxes & fees

3 Nov - 4 Nov

A high-rise hotel with multiple floors, large windows, and a prominent Tiffany & Co. store on the ground level.

A modern indoor pool area with large windows, potted palm plants, and lounge chairs.

A rooftop bar with seating and a view of the city skyline at night.

A spacious hotel lobby with multiple seating areas, a grand staircase, and large windows offering views of the city.

7. The Peninsula Chicago

Streeterville, 12 km from University of Chicago Medicine

Levi

฿21,050

฿25,026 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a sofa, a desk with a coffee maker, and a TV.

A modern lobby with a sofa set, a coffee table, and a large abstract wall art piece.

A modern reception area with a wooden reception desk, a seating area with sofas and a coffee table, and a large wall-mounted artwork.

8. Hyatt Place Chicago Midway Airport

11.5 km from University of Chicago Medicine

michele

฿5,119

฿6,014 total

includes taxes & fees

2 Nov - 3 Nov

A cityscape with a river, a bridge, and a dining area with tables and chairs.

A modern hotel room with large floor-to-ceiling windows offering a city view.

A high-rise hotel with a prominent 'TRUMP' sign, reflecting in the water, surrounded by other tall buildings.

A pool area with a view of a cityscape, a lounge with wicker furniture, and a person relaxing in the pool.

9. Trump International Hotel & Tower Chicago

River North, 11.3 km from University of Chicago Medicine

Mark

฿15,535

฿18,469 total

includes taxes & fees

1 Nov - 2 Nov

The Riu Plaza Chicago Hotel facade with a grand entrance, large windows, and a modern architectural design.

A couple dining at a table with a city view, surrounded by chairs and a variety of dishes.

A bar area with a marble countertop, bar stools, and a variety of bottles.

A modern hotel lobby with a central seating area, a reception desk, and a decorative wall with a unique design.

10. Hotel Riu Plaza Chicago

Streeterville, 11.7 km from University of Chicago Medicine

Denys

฿5,403

฿7,384 total

includes taxes & fees

2 Nov - 3 Nov

A modern restaurant interior with a green wall, hanging lights, and a long dining area.

A hotel lobby with a large Christmas tree, a sofa with red and white pillows, a glass coffee table, and a large window with a view of the street.

A rooftop lounge with green cushioned seating, a small round table, and a view of city buildings.

A modern interior with wooden flooring, black furniture, and large windows offering city views.

11. Hotel 505 River North

River North, 11.6 km from University of Chicago Medicine

Giana

฿7,713

฿10,248 total

includes taxes & fees

2 Nov - 3 Nov

A modern kitchen with a large island, bar stools, and a city view.

A modern living room with a grey sectional sofa, a round coffee table, and a glass desk with a chair. Large windows offer a city view.

A high-rise building with multiple floors, large windows, and a modern architectural design.

A spacious living area with a large sofa, a dining table, and a TV mounted on the wall.

12. Level Chicago – Old Town

Near North Side, 13 km from University of Chicago Medicine

Brian

฿7,644

฿9,805 total

includes taxes & fees

2 Nov - 3 Nov

A modern bar area with a long counter, multiple bar stools, and a variety of bottles on shelves.

A spacious restaurant with high ceilings, large windows, and a variety of seating arrangements including tables and chairs.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A spacious indoor area with a long table, multiple chairs, a sofa, and several gaming machines.

13. Hilton Chicago/Oak Lawn

13.5 km from University of Chicago Medicine

Arnetta

฿4,375

฿5,031 total

includes taxes & fees

15 Oct - 16 Oct

A swimming pool with a lifeguard station, chairs, and a clock on the wall.

A Fairfield Inn & Suites by Marriott hotel with a parking lot and a sign indicating handicap accessibility.

A vending machine stocked with snacks and beverages, located in a corner of a room with wooden paneling.

14. Fairfield Inn and Suites by Marriott Chicago Midway Airport

11.7 km from University of Chicago Medicine

Carol

฿3,656

฿4,295 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a central seating area, a reception desk, and a modern chandelier.

A banquet hall with round tables, chairs, and blue tablecloths.

A hotel lobby with seating areas, a patterned carpet, and a large mirror.

A restaurant with a bar area, multiple dining tables, and chairs.

15. DoubleTree by Hilton Chicago - Alsip

18.2 km from University of Chicago Medicine

Renaulda

฿4,065

฿4,593 total

includes taxes & fees

1 Nov - 2 Nov

A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, with large windows offering views of the outdoors.

A spacious indoor dining area with high ceilings, large windows, and a mix of seating options including tables and chairs.

A hotel entrance with a clear sky, an American flag, and a sign reading "Hampton Inn Suites".

A modern hotel room with a bed, white linens, a headboard with artwork, bedside lamps, and a small bedside table.

16. Hampton Inn & Suites Bridgeview Chicago

16.5 km from University of Chicago Medicine

firas

฿3,809

฿4,265 total

includes taxes & fees

2 Nov - 3 Nov

A modern indoor swimming pool with a clear blue water surface, a wooden ceiling, and a wall with a floral pattern.

A modern lobby with a sofa, a coffee table, and a vase of flowers.

A modern hotel room with a large window offering a city view, a wooden desk with a laptop, and a small seating area.

A rooftop terrace with a view of a city skyline at dusk.

17. Nobu Hotel Chicago

11.3 km from University of Chicago Medicine

Abhay

฿15,316

฿19,051 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with a fire pit, wicker furniture, and a brick wall.

A lobby with a stone fireplace, seating area, and a TV screen.

A modern hotel with a brick facade, multiple windows, and a well-maintained lawn.

A modern hotel room with a grey sofa, a small table, a dining area with blue chairs, a kitchen area, and a framed artwork on the wall.

18. Residence Inn Marriott Chicago Midway

11.9 km from University of Chicago Medicine

Jesse

฿6,711

฿7,884 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a large TV, a sofa, a coffee table, and a chair. There is a large window with a city view.

A rooftop patio with outdoor seating, a fire pit, and a city view.

A bedroom with a large window overlooking a cityscape.

A modern bedroom with a large bed, a television, and a balcony with a city view.

19. Level Chicago - River North

11.7 km from University of Chicago Medicine

Frederico

฿5,940

฿7,804 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a grey sofa, a coffee table, and a bookshelf filled with books.

A cozy library with wooden tables and chairs, bookshelves, and a television.

A red building with multiple flags, a sign reading "AMAZON HOUSE," and a storefront with a sign that says "COUNTRY HOUSE."

A hallway with a brick wall, a chandelier, and framed pictures.

20. Chicago Parthenon Hostel

10.5 km from University of Chicago Medicine

Krasimir

฿3,941

฿4,626 total

includes taxes & fees

2 Nov - 3 Nov

View all properties

Compare popular hotels close to University of Chicago Medicine

Property	Property class	Guest rating
Sophy Hyde Park	9.4 Exceptional 1,004 reviews	View
Chicago Lake Shore Hotel	7.0 Good 1,004 reviews	View
Best Motel By OYO Chicago I-90	3.4 147 reviews	View
Hampton Inn & Suites Chicago Medical District UIC	9.6 Exceptional 784 reviews	View
Holiday Inn Express Hotel & Suites Chicago-Midway Airport by IHG	9.0 Wonderful 1,375 reviews	View

Top University of Chicago Medicine Hotel Reviews

Sophy Hyde Park

10/10 Excellent

"Great restaurants and museums within safe walking distance."

Congress Plaza Hotel

8/10 Good

"Old hotel! Front desk wasn’t helpful l, ask for several things and they never showed up. No A.C., coffee pot broken, ran out of toilet paper and towels. No ice in machine, vending machine served hot beverages. Maintenance men were very nice, Christian at the bar was excellent! I’ll never stay there again."

Hyatt Regency McCormick Place Chicago

8/10 Good

"Everything was great!!! We will be back. It was a great location for visiting the Obama Presidential center"

Chicago Lake Shore Hotel

10/10 Excellent

"Definitely a motel vibe, no elevator. Nice staff and clean rooms."

Chinatown Hotel Chicago

10/10 Excellent

"Great place for a peace of mind beautiful area everything you can think is in walking distance"

SpringHill Suites by Marriott Chicago Chinatown

10/10 Excellent

"Room was clean, spacious bathroom. Breakfast was great."

Villa Dubois Guest House

10/10 Excellent

"Wonderful place"

Mccormick Place Guest House

8/10 Good

"I had a wonderful stay at the DuBois McCormick Place Guest House. The location was very convenient, especially for visiting McCormick Place and exploring the surrounding area. The room was clean, comfortable, and well maintained. I also appreciated the peaceful atmosphere and the overall attention to detail. The guest house offered a comfortable home base after a busy day, with everything needed for a pleasant stay. I would happily recommend the DuBois McCormick Place Guest House to both business and leisure travelers, and I look forward to staying there again."

McCormick Suites by Slumber Stay

10/10 Excellent

"It was an above-average stay."

Frequently asked questions

What's the area like around University of Chicago Medicine?

University of Chicago Medicine is located in a vibrant area of Chicago known for its beautiful lakeside setting and stunning architecture. If you're looking for a convenient place to stay, take a look at the 78 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near University of Chicago Medicine?

Sophy Hyde Park is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a fitness centre. It's located 1 mi (1.6 km) from University of Chicago Medicine. Other good choices within 5 miles include Chicago Lake Shore Hotel and Best Motel By OYO Chicago I-90.

How many hotels are there close to University of Chicago Medicine?

Expedia has 78 hotels and other accommodation options within a mile from University of Chicago Medicine.

If I need to cancel the hotel reservation for my stay near University of Chicago Medicine, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best options available near University of Chicago Medicine.

What can I see and do near University of Chicago Medicine?

You might want to spend some time browsing the exhibits at Griffin Museum of Science and Industry, DuSable Black History Museum and Education Center or Stony Island Arts Bank. Explore landmarks like Barack Obama Residence, Wabash Ave YMCA and Ida B Wells House. You can watch performances at Arie Crown Theater, Radius - Chicago and Court Theatre if you're interested in local theatre.

How can I get to University of Chicago Medicine?

If you'd like to explore more of the area, jump aboard a train from Chicago 55th-56th-57th Street Station, Chicago 59th Street Station or Chicago 51st-53rd Street Station (Hyde Park). There might not be many public transport options to choose from close to University of Chicago Medicine so consider a car rental to maximise your time.

Search Hotels Near University of Chicago Medicine, Chicago

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for University of Chicago Medicine hotels

1. Sophy Hyde Park

2. Chicago Lake Shore Hotel

3. Best Motel By OYO Chicago I-90

4. Hampton Inn & Suites Chicago Medical District UIC

5. Holiday Inn Express Hotel & Suites Chicago-Midway Airport by IHG

6. Hyatt Regency McCormick Place Chicago

7. The Peninsula Chicago

8. Hyatt Place Chicago Midway Airport

9. Trump International Hotel & Tower Chicago

10. Hotel Riu Plaza Chicago

11. Hotel 505 River North

12. Level Chicago – Old Town

13. Hilton Chicago/Oak Lawn

14. Fairfield Inn and Suites by Marriott Chicago Midway Airport

15. DoubleTree by Hilton Chicago - Alsip

16. Hampton Inn & Suites Bridgeview Chicago

17. Nobu Hotel Chicago

18. Residence Inn Marriott Chicago Midway

19. Level Chicago - River North

20. Chicago Parthenon Hostel

Compare popular hotels close to University of Chicago Medicine

Top University of Chicago Medicine Hotel Reviews

Sophy Hyde Park

Congress Plaza Hotel

Hyatt Regency McCormick Place Chicago

Chicago Lake Shore Hotel

Chinatown Hotel Chicago

SpringHill Suites by Marriott Chicago Chinatown

Villa Dubois Guest House

Mccormick Place Guest House

McCormick Suites by Slumber Stay

Frequently asked questions