The Best Hotels in St. Mary's, San Francisco - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for St. Mary's hotels

An outdoor seating area with wicker furniture and a fire feature, adjacent to a bar and dining area with modern decor.

1. Hyatt Place San Francisco Downtown

5.8 km from St. Mary's

Greg

฿7,031 total

includes taxes & fees

1 Nov - 2 Nov

A multi-level hotel atrium with outdoor seating areas, a pool, and a central lounge.

2. Embassy Suites by Hilton San Francisco Airport Oyster Point

8.9 km from St. Mary's

guadalupe

฿5,472 total

includes taxes & fees

16 Oct - 17 Oct

A La Quinta hotel with a modern facade, a covered entrance, and a parking lot.

3. La Quinta Inn & Suites by Wyndham San Francisco Airport N

9.3 km from St. Mary's

Justin

฿5,297 total

includes taxes & fees

11 Oct - 12 Oct

A modern interior with a wooden partition, a stone accent wall, and a bar area.

4. DoubleTree by Hilton San Francisco Airport North Bayfront

7.4 km from St. Mary's

Kelcie

฿4,678 total

includes taxes & fees

9 Oct - 10 Oct

A bar area with a curved wooden counter, bar stools, and a glass display case filled with bottles.

5. Best Western Plus Grosvenor Airport Hotel

10.1 km from St. Mary's

Lori

฿4,305 total

includes taxes & fees

17 Oct - 18 Oct

A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

6. LUMA Hotel San Francisco

5.5 km from St. Mary's

Farukh

฿9,698 total

includes taxes & fees

31 Oct - 1 Nov

A buffet counter with coffee machines, a TV, and various food items.

7. Stanyan Park Hotel

4.6 km from St. Mary's

Arielle

฿8,187 total

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a bed, desk, chair, television, and a microwave.

8. Hotel Nova SFO

10.2 km from St. Mary's

Anne

฿5,629 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a large bed, a desk with a chair, a TV, and a view of the city.

9. Comfort Inn by the Bay

Cow Hollow, 7.5 km from St. Mary's

Antony

฿4,866 total

includes taxes & fees

1 Nov - 2 Nov

10. Sonesta Select San Francisco Airport Oyster Point Waterfront

7.9 km from St. Mary's

Sheila Marie

฿4,665 total

includes taxes & fees

17 Oct - 18 Oct

A modern hotel lobby with a seating area, a bar, and large windows.

11. Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf, 8.3 km from St. Mary's

Troy

฿6,219 total

includes taxes & fees

3 Nov - 4 Nov

A modern hotel with a sleek exterior and a parked sports car in front.

12. Hotel VIA

5.9 km from St. Mary's

David

฿7,785 total

includes taxes & fees

30 Oct - 31 Oct

A street leading to a building with a sign reading "Cow Palace".

13. Alpine Inn And Suites

2.8 km from St. Mary's

Alexander

฿4,666 total

includes taxes & fees

18 Oct - 19 Oct

A modern lobby with a cityscape mural, a reception desk, seating area, and a door with blinds.

14. Hotel Skye SFO

12.4 km from St. Mary's

Laurie

฿4,663 total

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with a central reception desk, large columns, and hanging pendant lights.

15. Hilton Garden Inn San Francisco Arpt North

8.7 km from St. Mary's

kathrina

฿3,848 total

includes taxes & fees

18 Oct - 19 Oct

A rooftop pool area with blue seating and a pool.

16. Holiday Inn Golden Gateway by IHG

Nob Hill, 6.3 km from St. Mary's

John

฿6,004 total

includes taxes & fees

25 Oct - 26 Oct

A reception area with a counter, two patterned chairs, a yellow ottoman, and a large blue potted plant.

17. Hotel Aura SFO

12.9 km from St. Mary's

Charles

฿4,500 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, seating area, and a high ceiling with chandeliers.

18. La Quinta Inn & Suites by Wyndham San Francisco Airport West

13.8 km from St. Mary's

Joy

฿5,389 total

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, a sofa, a nightstand, and a desk. There are three framed pictures on the wall.

19. The Atrium Hotel

11.5 km from St. Mary's

Ramesh

฿4,941 total

includes taxes & fees

11 Oct - 12 Oct

A spacious, well-lit atrium with a high ceiling and skylight, featuring a central seating area with a sofa and armchairs, surrounded by a patterned rug.

20. Hotel Aluxor SFO

12.3 km from St. Mary's

Kenna

฿4,145 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Where to stay in St. Mary's

Find the best St. Mary's areas for the activities you enjoy most.

A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

See properties

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

See properties

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

See properties

A city street with tall buildings, flags, and cars.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

See properties

A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

See properties

Top St. Mary's Hotel Reviews

Hilton San Francisco Union Square

10/10 Excellent

"（"

Handlery Union Square Hotel

8/10 Good

"This hotel is in a great location. Easy walking distance from Powell station. Tons of shopping and restaurants nearby. Staff was very friendly! There was an elevator out of service all weekend- which was a bit of a pain because there was TON of events going on in the city so the hotel was packed. My room was small but it was fine for what I needed it for. It’s a bit old, overall clean enough. My housekeeper was great and very attentive. The pool is not THAT heated, especially since the courtyard is mostly in the shade it was too chilly to take a dip- wish there was a hot tub! I do wish the coffee service went longer it seemed to run out each day"

The Marker Union Square San Francisco

10/10 Excellent

"The Marker is a nice retreat a couple of blocks off of Union Square. It's a short walk down to Market for Muni rides or over to Powell to catch the cable car. The room was well appointed with a comfortable bed and pillows. I appreciated the water bottles in the room that the staff refreshed daily as I used them. Water pressure in the shower was excellent. The library in the lobby was a nice place to hang out for a bit rather than sitting in the room. Not to detract from a free perk, but the complimentary coffee manged to taste watered down but burnt at the same time. After dumping that out I bought a $9 12oz latte at Tratto that was also underwhelming. After that, I went elsewhere for breakfast. Overall, I would happily stay here again."

Frequently asked questions

What is St. Mary's like?

Travellers to San Francisco's St. Mary's neighbourhood will be sure to enjoy a stay here.

If I need to cancel my hotel reservation in St. Mary's, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals in St. Mary's.

What is there to do in this San Francisco neighbourhood?

Harry Steps, Esmeralda Slide Park and Knockout are just a few of the places to visit in and around St. Mary's. El Rio and Mothership are also worth a visit when you're out sightseeing in San Francisco.

Explore a world of travel with Expedia

More ways to book

Book Hotels in St. Mary's on Expedia.com

Search Hotels in St. Mary's, San Francisco

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Mary's hotels

1. Hyatt Place San Francisco Downtown

2. Embassy Suites by Hilton San Francisco Airport Oyster Point

3. La Quinta Inn & Suites by Wyndham San Francisco Airport N

4. DoubleTree by Hilton San Francisco Airport North Bayfront

5. Best Western Plus Grosvenor Airport Hotel

6. LUMA Hotel San Francisco

7. Stanyan Park Hotel

8. Hotel Nova SFO

9. Comfort Inn by the Bay

10. Sonesta Select San Francisco Airport Oyster Point Waterfront

11. Hotel Riu Plaza Fisherman's Wharf

12. Hotel VIA

13. Alpine Inn And Suites

14. Hotel Skye SFO

15. Hilton Garden Inn San Francisco Arpt North

16. Holiday Inn Golden Gateway by IHG

17. Hotel Aura SFO

18. La Quinta Inn & Suites by Wyndham San Francisco Airport West

19. The Atrium Hotel

20. Hotel Aluxor SFO

Where to stay in St. Mary's

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top St. Mary's Hotel Reviews

Hilton San Francisco Union Square

Frequently asked questions

Explore a world of travel with Expedia