The Best Hotels in Santissima Annunziata, Florence - 2026 Updated Prices

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Compare popular hotels in Santissima Annunziata

Property	Property class	Guest rating
Alfieri9	3.0 star property	9.6 Exceptional 170 reviews	View
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World	5.0 star property	10.0 Exceptional 23 reviews	View
3110 ArtHotel	3.0 star property	9.4 Exceptional 232 reviews	View
Loggiato dei Serviti	3.0 star property	9.6 Exceptional 527 reviews	View
Four Seasons Hotel Firenze	5.0 star property	9.8 Exceptional 310 reviews	View

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas for the activities you enjoy most.

A river with buildings on the right bank.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

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A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

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A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

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A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

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An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

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Top Santissima Annunziata Hotel Reviews

Hotel Astro Mediceo

8/10 Good

"Very nice property, lovely staff. Super convenient location if you have a car. An easy walk into the center, and an easy exit from town. Dont miss mercato in Piazza Cure, just on the other side of the train tracks. 4 stars because the beds were classically terrible, hard italian mattresses with equally flat pillows and because despite a request, our mini fridge didnt work. Also, their parking lot behind the property is quite small and you need to call ahead to ensure they save you a spot. The staff were ULTRA helpful and managed to wedge us in and back us out as well. I would consider staying here again...esp if the bedding were improved. :)"

Forte16 View & Spa

10/10 Excellent

"Here’s a polished review you could post: We had a fantastic stay at Forte16. The staff were absolutely exceptional throughout our visit – welcoming, friendly, and always happy to help with anything we needed. The parking experience was excellent and made arriving and exploring Florence by car completely stress-free, which is a real bonus. Our room was spotless, modern, and very comfortable, and the facilities were excellent. We especially enjoyed the pool, which was a great place to relax after a busy day sightseeing. Overall, a wonderful hotel with outstanding service. We wouldn’t hesitate to stay here again and would highly recommend Forte16 to anyone visiting Florence."

Hotel Le Due Fontane

10/10 Excellent

"My wife broke her leg in Florence and was put into a cast by the hospital. The staff at this hotel was so helpful, trying to attend to her needs. They even gave us an additional room for free for my wife since our room did not have lift access, so we then occupied two rooms for the remainder of our stay (cut short, as we needed to go home early) I have to commend the compassion of each individual hotel staff member."

3110 ArtHotel

10/10 Excellent

"Cute, artsy boutique hotel in a quiet part of town, close to groceries and a few great restaurants. The bus stop is pretty much right outside the door, and the tram to the center and airport also just a few blocks away. Our room was spacious and clean, the AC worked well. The king size bed and sofa/twin bed was perfect for a couple and 12-year-old. The bathroom and shower in particular are a bit small, but perfectly fine. Good water pressure, and my husband loved the bidet! We also enjoyed the buffet breakfast with indoor and outdoor patio seating. The staff was helpful and friendly. Would definitely stay here again!"

Frequently asked questions

What's it like in Santissima Annunziata?

Santissima Annunziata is an historic neighbourhood known for its picturesque gardens and cycling. Make sure that you visit Statue of David and Gallery of the Academy of Florence as part of your Santissima Annunziata travel plans.

What's a favourite place to stay in Santissima Annunziata?

Based on our traveller data, Hotel Regency is one of the top choices for your stay in Santissima Annunziata. This hotel is a short 15-minute walk from Piazza del Duomo, and it offers free breakfast and a restaurant. Other good options for your stay in the area include Four Seasons Hotel Firenze and Hotel Astro Mediceo.

How many hotels will I be able to find in the Santissima Annunziata area?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 500 Santissima Annunziata hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Santissima Annunziata, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer in Santissima Annunziata.

What are the top things to see and do in Santissima Annunziata?

Attractions such as Gallery of the Academy of Florence, Museo degli Innocenti and Teatro Le Laudi highlight Florence's cultural scene. Statue of David and Piazza Donatello are also a couple of places to visit in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Piazza del Duomo, Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella. English Cemetery and Palazzo Capponi are also worth a visit when you're out sightseeing in Florence.

How can I get around Santissima Annunziata and the greater Florence area?

If you're considering venturing out of town, train travel is a great option. Florence Campo di Marte Station is the closest train station, but Florence (FIR-Firenze Campo di Marte Rail Station) and Florence-Le Cure Station are also close by.

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Our top choices for Santissima Annunziata hotels

1. Four Seasons Hotel Firenze

2. Hotel Regency

3. Hotel Meridiana

4. Forte16 View & Spa

5. Hotel Villa Il Castagno

6. Alfieri9

7. Hotel Villa Liana

8. Loggiato dei Serviti

9. Numa Florence della Robbia

10. Messori Suites

11. Pier Capponi 17 Room & Suites

12. Guest House Morandi

13. Firenze Residence

14. 3110 ArtHotel

15. Hotel Emma

16. The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

17. Villa Tortorelli

18. Hotel Masaccio Florence

19. De La Pace, Sure Hotel Collection by Best Western

20. Palazzo Lombardo

Compare popular hotels in Santissima Annunziata

Where to stay in Santissima Annunziata

Historic Centre of Florence

Duomo

San Giovanni

Santa Maria Novella

Santa Croce

Top Santissima Annunziata Hotel Reviews

Hotel Astro Mediceo

Frequently asked questions

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