Find hotels in Sant'Onofrio from ฿2,141

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant'Onofrio hotels

Elite Room | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds
Palermo Inn Boutique Hotel

Palermo Inn Boutique Hotel

Palermo Inn Boutique Hotel
Palermo Historical Center
9.2 out of 10, Wonderful, (12)
"Nice clean place, completely renovated and new. Staff was more than helpful before and during our stay. Breakfast was the one of the best on our travels throughout Sicily. The surrounding streets around the hotel could use some sprucing up."
United States
Michael
The price is ฿12,760
฿14,329 total
includes taxes & fees
26 Dec - 27 Dec
Palermo Inn Boutique Hotel
Luxury Studio Suite, 1 Bedroom | Premium bedding, down duvets, pillow-top beds, minibar
Vossia Luxury Rooms & Sicilian Living

Vossia Luxury Rooms & Sicilian Living

Vossia Luxury Rooms & Sicilian Living
Palermo Historical Center
9.8 out of 10, Exceptional, (78)
"I will definitely return as the room was spacious and cozy and the staff was helpful!"
United States
Julianne
The price is ฿4,975
฿5,765 total
includes taxes & fees
13 Jan - 14 Jan 2026
Vossia Luxury Rooms & Sicilian Living
Superior Deluxe Apartment | View from room
Palazzo Sovrana

Palazzo Sovrana

Palazzo Sovrana
Palermo Historical Center
9.6 out of 10, Exceptional, (181)
"Excelente Hotel"
Mexico
Jorge
The price is ฿7,218
฿8,232 total
includes taxes & fees
9 Jan - 10 Jan 2026
Palazzo Sovrana
Property entrance
Family Affair

Family Affair

Family Affair
Politeama
9.8 out of 10, Exceptional, (150)
"A lovely place with good service"
United States
Cheryl
The price is ฿3,444
฿4,081 total
includes taxes & fees
6 Jan - 7 Jan 2026
Family Affair
Deluxe Room | Minibar, in-room safe, desk, blackout curtains
Quintocanto Hotel and Spa

Quintocanto Hotel and Spa

Quintocanto Hotel and Spa
4.0 star property
Palermo Historical Center
8.4 out of 10, Very good, (509)
"Really cool hotel with an excellent restaurant. Outside the hotel is very busy with tourists and restaurants but the room was quiet with minimal outside noise "
United Kingdom
Christopher
The price is ฿2,995
฿3,624 total
includes taxes & fees
2 Jan - 3 Jan 2026
Quintocanto Hotel and Spa
Lobby sitting area
Casa Nostra Boutique Hotel

Casa Nostra Boutique Hotel

Casa Nostra Boutique Hotel
Palermo Historical Center
8.4 out of 10, Very good, (43)
"It is always amazing to stay here "
Canada
Elliot
The price is ฿4,792
฿5,563 total
includes taxes & fees
5 Jan - 6 Jan 2026
Casa Nostra Boutique Hotel
Deluxe Double Room (Vista mare o vista giardino) | Egyptian cotton sheets, premium bedding, down duvets, minibar
BB 22 Charming Rooms & Apartments

BB 22 Charming Rooms & Apartments

BB 22 Charming Rooms & Apartments
Palermo Historical Center
9.4 out of 10, Exceptional, (65)
"Great place to stay within walking distance to lots of the places you would want to go"
United Kingdom
Calum
The price is ฿2,965
฿3,554 total
includes taxes & fees
7 Jan - 8 Jan 2026
BB 22 Charming Rooms & Apartments
Family Triple Room, Non Smoking, Balcony | Balcony view
Bellaroto Suite & Spa

Bellaroto Suite & Spa

Bellaroto Suite & Spa
1.0 star property
Palermo Historical Center
9.6 out of 10, Exceptional, (102)
"Staff were excellent and responsive"
United States
Theresa
The price is ฿4,393
฿5,125 total
includes taxes & fees
8 Jan - 9 Jan 2026
Bellaroto Suite & Spa
Daily buffet breakfast (EUR 12.50 per person)
Delle Vittorie Luxury Suites & Rooms

Delle Vittorie Luxury Suites & Rooms

Delle Vittorie Luxury Suites & Rooms
3.0 star property
Palermo Historical Center
9.6 out of 10, Exceptional, (502)
"The room was very clean. Martina was extremely helpful with providing transportation and recommending things to do. Location is excellent Walking distance to shopping and eateries."
United States
Florence
Delle Vittorie Luxury Suites & Rooms
Deluxe Suite | Premium bedding, memory-foam beds, in-room safe, individually decorated
Suite 136 Luxury Rooms

Suite 136 Luxury Rooms

Suite 136 Luxury Rooms
Politeama
8.8 out of 10, Excellent, (98)
"Great Location. Very friendly & helpful staff. Clean rooms & complimentary coffee."
Canada
Daniel
Suite 136 Luxury Rooms
Standard Double Room | Free minibar items, in-room safe, desk, laptop workspace
Alma Hotel

Alma Hotel

Alma Hotel
3.0 star property
Politeama
9.6 out of 10, Exceptional, (567)
"This hotel is perfect. Breakfast is great, you can walk anywhere, I slept wonderfully, and the staff is amazing. Stay here, don’t look anywhere else."
United States
Christopher
Alma Hotel
Terrace/patio
Sant'Agostino B&B

Sant'Agostino B&B

Sant'Agostino B&B
3.0 star property
Palermo Historical Center
9.6 out of 10, Exceptional, (247)
"We had a wonderful stay at this hotel. Our apartment had two bedrooms with beautiful view from the private terrace. The hotel has excellent location in the old town and all attractions are within walking distance. Breakfast was great with many options. Our room was kept clean and tidy all the time. Fanny the manager and all the staff were very attentive and helpful and made our stay very enjoyable. We highly recommend this hotel."
United Kingdom
Zuhair Jerjese
Sant'Agostino B&B
Luxury Room | Premium bedding, down duvets, memory-foam beds, minibar
Fervore Luxury Rooms

Fervore Luxury Rooms

Fervore Luxury Rooms
3.0 star property
Politeama
10.0 out of 10, Exceptional, (27)
"Amazing stay highly recommend. Attentive staff amazing breakfast great location."
United States
Geralyn
The price is ฿3,444
฿4,081 total
includes taxes & fees
17 Jan - 18 Jan 2026
Fervore Luxury Rooms
Reception
Dimora Bellini residenza d' epoca

Dimora Bellini residenza d' epoca

Dimora Bellini residenza d' epoca
3.0 star property
Palermo Historical Center
9.2 out of 10, Wonderful, (132)
"Beautiful boutiques hotel and perfect location. We loved it and plan to come back. We will definitely recommend it to our family and friends when they come to visit us here in Sicily. "
United States
Michelle
The price is ฿2,251
฿2,769 total
includes taxes & fees
28 Dec - 29 Dec
Dimora Bellini residenza d' epoca
Standard Double Room, City View | In-room safe, desk, soundproofing, iron/ironing board
Real Fonderia b&b

Real Fonderia b&b

Real Fonderia b&b
Palermo Historical Center
9.4 out of 10, Exceptional, (46)
"Room was very comfortable, small terrace was nice. Walkable to the city center."
United States
Sean
Real Fonderia b&b
Junior Studio Suite | Free WiFi, bed sheets
Terre di Himera

Terre di Himera

Terre di Himera
4.0 star property
Termini Imerese
9.6 out of 10, Exceptional, (43)
"Beautiful location, great views, locally sourced food and hosts were very friendly and knowledgeable! Breakfast is worth the visit alone…..superb stay!"
United Kingdom
Gareth
The price is ฿7,853
฿8,639 total
includes taxes & fees
27 Dec - 28 Dec
Terre di Himera
Property entrance
Porta di Castro Hotel & Spa

Porta di Castro Hotel & Spa

Porta di Castro Hotel & Spa
1.0 star property
Palermo Historical Center
9.4 out of 10, Exceptional, (409)
"Excellent hotel, great location and wonderful staff"
United States
Kim
Porta di Castro Hotel & Spa
Seasonal outdoor pool
Rocco Forte Villa Igiea

Rocco Forte Villa Igiea

Rocco Forte Villa Igiea
5.0 star property
Monte Pellegrino
9.6 out of 10, Exceptional, (97)
"I love this place"
United States
David
The price is ฿15,640
฿17,570 total
includes taxes & fees
4 Jan - 5 Jan 2026
Rocco Forte Villa Igiea
Coffee/tea maker, electric kettle
BB 10 Serpotta

BB 10 Serpotta

BB 10 Serpotta
Politeama
9.4 out of 10, Exceptional, (157)
"Nice clean facility. "
United States
Jose
The price is ฿2,096
฿2,599 total
includes taxes & fees
6 Jan - 7 Jan 2026
BB 10 Serpotta
View from property
Kala Rooms

Kala Rooms

Kala Rooms
Palermo Historical Center
9.4 out of 10, Exceptional, (161)
"We really enjoyed our stay there!"
Germany
Patrick
Kala Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Sant'Onofrio Hotel Reviews

inCanto

inCanto

10/10 Excellent
"Amazing experience!"
Gina 4-night trip
Posted 1 month ago
inCanto
Astoria Palace Hotel

Astoria Palace Hotel

10/10 Excellent
"Stayed for 5 nights. Excellent service and helpful pleasant staff. Comfortable large clean lobby. Rooms cleaned and towels changed punctually everyday. Excellent breakfast. Very convenient location for going in any direction. The fastest elevators ! "
Majid Reza 5-night trip
Posted 4 months ago
Astoria Palace Hotel

More cheap stays in Sant'Onofrio

Hotel City Center

Hotel City Center

Via Mariano Stabile, 139 Palermo PA
The price is ฿1,713 per night from 12 Jan to 13 Jan
฿1,713
฿2,141 total
12 Jan - 13 Jan 2026
includes taxes & fees
8/10 Very Good! (47 reviews)

Frequently asked questions

What's the best place for a stay in Sant'Onofrio?
Hotel Politeama, located 16.4 mi (26.3 km) from the heart of Sant'Onofrio, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are Rocco Forte Villa Igiea and Hotel Plaza Opera. See all available top hotels, or vacation rentals in Sant'Onofrio.
What are some of the best holiday rentals that Sant'Onofrio has to offer?
Vucciria Apartments By Wonderful Italy: This holiday home rental outside of Sant'Onofrio has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a dishwasher and a stovetop. See all vacation rentals in Sant'Onofrio.
If I need to cancel my hotel reservation in Sant'Onofrio, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sant'Onofrio.
What's the best hotel to stay near the beach in Sant'Onofrio?
Torre Artale Hotel & Residence is a top hotel with a free beach shuttle and sunloungers, and it's located close to the beach . See more stays near the beach in Sant'Onofrio.
What are some hotels with pools in Sant'Onofrio?
Rocco Forte Villa Igiea: Hotel, 1-minute walk from Palermo Harbour. Offers a full-service spa, a seasonal outdoor pool and a snack bar/deli. Another option with an on-site pool is Grand Palladium Sicilia Resort & Spa. View all hotels with pools in Sant'Onofrio.
What is staying in Sant'Onofrio like?
Those travelling to Sant'Onofrio will definitely enjoy the sights to see and things to do. In Sant'Onofrio, there are 7 hotels and other accommodation options to choose from. Find out more about Sant'Onofrio.
What should I do while I'm visiting Sant'Onofrio?
Places to visit in the wider area include Caccamo Castle, Sant'Elia Beach and Carlo Alberto Dalla Chiesa and Emanuela Setti Carraro Sports Hall. You'll also find Capo Mongerbino and Himera in the area. Take a look at what more there is to see and do in Expedia's Sant'Onofrio guide.
What's the seasonal weather in Sant'Onofrio?
The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for Sant'Onofrio is 711 mm.