San Francisco Travel Guide

Panama City

Photo by Hideki Yamagata
Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Nóra Széll
Photo by Panama Roadrunner
Photo by Panama Roadrunner

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall

ATLAPA Conventions Center

Learn about the events happening in ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area or visit its lively bars.

ATLAPA Conventions Center

Pacific Center

You can find the perfect gifts to bring home at Pacific Center during your visit to Panama City. Visit the shops and lively bars in this romantic area.

Pacific Center

Multicentro Panama

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

Multicentro Panama

Panama Canal Murals

You can learn about the history of Panama City with a stop at Panama Canal Murals. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.

Panama Canal Murals

Hospital Punta Pacífica

If Hospital Punta Pacífica is what brings you to town, hopefully you'll have a chance to explore more of Panama City.

Hospital Punta Pacífica

Things to do

Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

฿4,880
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

฿2,424
per adult
96% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
La casa de papel Day tour in San Blas Islands - All inclusive- No hidden fees.

All included - Day tour in San Blas Islands - No extra fees

฿3,570
per adult
All included - Day tour in San Blas Islands - No extra fees
Full-Day SAN BLAS ISLAND & Snorkeling Tour + Transport from Panama City

Full-Day SAN BLAS ISLAND Tour + Transport from Panama City

฿4,684
per adult
Full-Day SAN BLAS ISLAND Tour + Transport from Panama City
3-Hour Private Custom Tour with a Local Guide in Panama City

Panama City : Custom Walking Tour with A Guide (Private Tour)

฿1,945
per adult
Panama City : Custom Walking Tour with A Guide (Private Tour)
Live the Experience of a Full Day in San Blas

Live the Experience of a Full Day in San Blas

฿5,077
per adult
100% of travellers recommend
Live the Experience of a Full Day in San Blas
See all activities in Panama City

Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundable
The price is ฿4,111 per night from 31 Aug to 1 Sept
฿4,111
฿4,522 total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (925 reviews)
"El hotel es super lindo y el desayuno es muy bueno. La atención también excelente."

Reviewed on 6 Aug 2025

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is ฿7,145 per night from 30 Aug to 31 Aug
฿7,145
฿7,860 total
30 Aug - 31 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,000 reviews)
"service 100/100"

Reviewed on 9 Aug 2025

JW Marriott Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is ฿4,123 per night from 5 Sept to 6 Sept
฿4,123
฿4,535 total
5 Sept - 6 Sept
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,015 reviews)
"Everything was fantastic, however the bed sheets could be a little more clean, restock paper towel or hand towel in the bathroom and restock drinks as well as water :). The bathroom could be little more clean. Other than that everything was perfect."

Reviewed on 10 Aug 2025

Megapolis Hotel Panamá
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is ฿3,084 per night from 22 Aug to 23 Aug
฿3,084
฿3,393 total
22 Aug - 23 Aug
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,284 reviews)
"Good"

Reviewed on 15 Aug 2025

Decapolis Hotel Panama City
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is ฿3,642 per night from 14 Sept to 15 Sept
฿3,642
฿4,006 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,007 reviews)
"Adrialo was very helpful with information and suggested some great places for us to check out. Super nice guy"

Reviewed on 13 Aug 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is ฿5,132 per night from 17 Aug to 18 Aug
฿5,132
฿5,645 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,104 reviews)
"We only stayed one night. It is a very pleasant hotel… clean, well staffed, and maintained. The breakfast brunch was a very nice surprise, very good and a lot of options. I would highly recommend."

Reviewed on 11 Aug 2025

Plaza Paitilla Inn Hotel
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Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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El Cangrejo

4/5(5 area reviews)

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo
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Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

Bella Vista

San Francisco Travel Guide