Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tijuana: Guided City Tour with Local Food and Beer Tasting
฿3,762
per adult
Tijuana Downtown Self Guided Walking Tour
฿320
per adult
100% of travellers recommend
Stand up Paddle Board Lesson on The San Diego Bay
฿821
per adult
100% of travellers recommend
Top hotels in Otay Mesa
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
The price is ฿9,295 per night from 9 Aug to 10 Aug
฿9,295
฿12,446 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,727 reviews)
"Unexpected $50 nightly per car parking fee and an add on $50 per day resort fee. It's a good place but no longer worth the add on fees."
Reviewed on 10 Jul 2026
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is ฿5,066 per night from 3 Aug to 4 Aug
฿5,066
฿7,032 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,291 reviews)
"Honestly I was expecting much, much worse based on the reviews I had seen of this hotel so I was pleasantly surprised by most of the staff and the quality of the room. We were given our daily coffee vouchers, we had the same woman every morning and she was absolutely wonderful but I did not catch ..."
Reviewed on 10 Jul 2026
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿4,102 per night from 10 Aug to 11 Aug
฿4,102
฿4,715 total
10 Aug - 11 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. ...
8/10 Very good! (3,709 reviews)
"The check-in lasted almost one hour. More than 20 people in a queue, because the hotel did not have the rooms ready, that was what they said. We arrived at 4:00PM, as many others, and got the key around 5:00PM."
Reviewed on 11 Jul 2026
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is ฿5,548 per night from 19 Jul to 20 Jul
฿5,548
฿8,045 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (4,022 reviews)
"They booked"
Reviewed on 11 Jul 2026
Handlery Hotel
950 Hotel Cir N San Diego CA
The price is ฿4,764 per night from 2 Aug to 3 Aug
฿4,764
฿5,476 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.4/10 Very good! (2,718 reviews)
"Room carpet is older, toilet moves and closet ceiling leak water in the middle of night. I stayed the hotel because of work related seminar held on the premise. Otherwise wont be my first choice staying san diego."
Reviewed on 11 Jul 2026
Bahia Resort Hotel
998 W Mission Bay Dr San Diego CA
The price is ฿8,740 per night from 9 Aug to 10 Aug
฿8,740
฿11,891 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge) and 24-hour room service. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (2,240 reviews)
"Great hotel"
Reviewed on 11 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Seaport Village are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Spreckels Theater – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
