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Find hotels in Mytilene from ฿2,014

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Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Mytilene hotels

Restaurant
Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
5.0 star property
Lesvos
8.6 out of 10, Excellent, (46)
"I booked a junior suite. The description does not match the room. The room was to have a balcony and it does not. It was a basic room of 30 square metres with two single beds pushed together and a chair and small table. The service was terrible. The person at teh front desk in the morning was rude and basically could not wait to get me out. This was out of character witht he wonderful hospitality elsewhere on the island. I would NEVER recommend this place. "
Canada
Alissa
Mythical Coast Wellness Retreat
Outdoor dining
The Loriet

The Loriet

The Loriet
4.0 star property
Lesvos
8.4 out of 10, Very good, (76)
"Nice place, good breakfast"
United States
Emre
The price is ฿2,594
฿2,951 total
includes taxes & fees
25 Dec - 26 Dec
The Loriet
Seasonal outdoor pool
Heliotrope Hotels

Heliotrope Hotels

Heliotrope Hotels
4.0 star property
Lesvos
8.6 out of 10, Excellent, (192)
"Nice and clean hotel , very big breakfast buffet, easy parking"
United States
AVRAM
The price is ฿2,798
฿3,175 total
includes taxes & fees
26 Dec - 27 Dec
Heliotrope Hotels
Exterior
Lasia Hotel

Lasia Hotel

Lasia Hotel
3.0 star property
Lesvos
9.4 out of 10, Exceptional, (14)
"Enjoyed our stay. Clean and friendly staff!"
United States
Angelos
The price is ฿1,923
฿2,362 total
includes taxes & fees
3 Jan - 4 Jan 2026
Lasia Hotel
Property entrance
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (159)
"Our experience in here was so great! Staff is so kind and helpful. breakfast is the best and the location is the best 💙"
United Kingdom
Ezgi
Theofilos Paradise Boutique Hotel
Front of property
ISSA Lesvos

ISSA Lesvos

ISSA Lesvos
Lesvos
9.6 out of 10, Exceptional, (21)
"Perfect for family, centre location"
Turkey
Nuri
The price is ฿2,678
฿2,951 total
includes taxes & fees
16 Jan - 17 Jan 2026
ISSA Lesvos
Outdoor pool, open 11:00 AM to 7:00 PM, pool umbrellas, pool loungers
Elysion Hotel

Elysion Hotel

Elysion Hotel
5.0 star property
Lesvos
9.2 out of 10, Wonderful, (46)
"very good place and the staffs took very good care for us, even to prepare special diet foods. Lovely place and next to sea."
Turkey
ANINDYA
Elysion Hotel
Free daily buffet breakfast
Porto Lesvos

Porto Lesvos

Porto Lesvos
2.0 star property
Lesvos
8.8 out of 10, Excellent, (25)
"I have stayed here before and the owner is a very pleasant person who enjoys talking to his customers about a wide range of topics. I usually stay for one night and then go to Scala Kalloni inland. It is a place where Birders go in April and May to see the birds arriving from Africa & on their way to mainland Europe."
United Kingdom
Christopher
Porto Lesvos
Exterior
Elies Residences

Elies Residences

Elies Residences
Lesvos
10.0 out of 10, Exceptional, (33)
"Beautiful quiet nice little place.Very cosy !!"
Australia
Sophia
The price is ฿3,911
฿4,303 total
includes taxes & fees
3 Jan - 4 Jan 2026
Elies Residences
Exterior
Paradisos studios

Paradisos studios

Paradisos studios
Lesvos
9.6 out of 10, Exceptional, (4)
"This hotel is owner operated. Owner directly helped me to check in. Room was clean and spacious. Phenomenal value for the money. It is the 3rd time we have stayed at Paradisos. "
United States
Chris
Paradisos studios
Deluxe Apartment, 1 Bedroom (B1) | 1 bedroom, in-room safe, desk, blackout curtains
Heliotrope The Studios

Heliotrope The Studios

Heliotrope The Studios
Lesvos
8.8 out of 10, Excellent, (51)
"The staff and reception was so helpful best staff in Greece we enjoyed our stay and it was a very early check in option too"
Turkey
Beril
The price is ฿2,247
฿2,480 total
includes taxes & fees
25 Dec - 26 Dec
Heliotrope The Studios
Bar (on property)
Oikies Small Elegant Houses

Oikies Small Elegant Houses

Oikies Small Elegant Houses
Lesvos
9.4 out of 10, Exceptional, (29)
"Great place! Don’t look for anywhere else!"
United States
ATAMAN
The price is ฿2,674
฿2,948 total
includes taxes & fees
6 Jan - 7 Jan 2026
Oikies Small Elegant Houses
Superior Apartment 1 | In-room safe, blackout curtains, soundproofing, iron/ironing board
Agora Apartments

Agora Apartments

Agora Apartments
Lesvos
10.0 out of 10, Exceptional, (2)
"Great facility, but do not use your car to reach the property. No close by parking, narrow streets. Great communication friendly staff. "
United States
Ali
The price is ฿4,141
฿4,555 total
includes taxes & fees
29 Dec - 30 Dec
Agora Apartments
Handrails in stairways
Studio 5

Studio 5

Studio 5
Lesvos
The price is ฿1,822
฿2,014 total
includes taxes & fees
11 Jan - 12 Jan 2026
Studio 5
Beach
ISSA Thermi

ISSA Thermi

ISSA Thermi
Lesvos
The price is ฿2,968
฿3,306 total
includes taxes & fees
11 Jan - 12 Jan 2026
ISSA Thermi
Deluxe Double Room, Balcony | Terrace/patio
Olive Green Studios and Apartments

Olive Green Studios and Apartments

Olive Green Studios and Apartments
Lesvos
10.0 out of 10, Exceptional, (3)
"Beautiful room with a fantastic view. "
Canada
lisa
The price is ฿4,943
฿5,470 total
includes taxes & fees
25 Dec - 26 Dec
Olive Green Studios and Apartments
Breakfast for a fee
Kaloni village apartments

Kaloni village apartments

Kaloni village apartments
Lesvos
8.4 out of 10, Very good, (7)
"Temiz ve doğa içinde apartlar gerçekten fiyatını karşılıyor. Ancak kaldığımız dairede çamaşır makinesi kapağı bozuktu ve tek sefer havluların yıkanması için bir çözüm rica ettim. bana elimle yıkayabileceği söylendi! Ayrıca bir gece düğün nedeniyle saat 03:15 e kadar çok yüksek sesli müzik çalındı. başka bir çok müşterinin konaklama yaptığı bir gece bu saygısızlık kabul edilemez. Kahvaltı oldukça kalitesizdi. "
Turkey
murat
Kaloni village apartments
Front of property – evening/night
Ouzo Stone House 1, with private pool

Ouzo Stone House 1, with private pool

Ouzo Stone House 1, with private pool
Lesvos
Ouzo Stone House 1, with private pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mytilene attractions

Mytilini Castle

4.6/5 (11 reviews)
Learn about the local history of Mytilene when you spend time at Mytilini Castle. While you're in the area, stroll along the seaside.
See properties

Bus Station

4.0/5 (1 review)
After visiting Bus Station, make a plan to see the other sights and activities in Mytilene. While you're in the area, stroll along the seaside.
See properties

Learn more about Mytilene

The harbour city's neoclassical mansions and Byzantine castle offer glimpses into its rich past as a trading centre. Explore the Archaeological Museum's ancient artefacts, then enjoy fresh seafood at tavernas along the waterfront promenade.

See all hotels in Mytilene
Mitylene Island, or better known as Lesvos, Greece. There seriously are 50 different shades of blue in this country. Enjoy practically empty beaches and amazing food on this sleepy little island just off the west coast of Turkey. http://www.hecktictravels.com/shades-of-blue #Greece #Lesvos #Travel
Photo by Hecktic Travels
Open Photo by Hecktic Travels

Top Mytilene Hotel Reviews

Agora Apartments

Agora Apartments

10/10 Excellent
"Great facility, but do not use your car to reach the property. No close by parking, narrow streets. Great communication friendly staff. "
Ali 1-night trip
Posted 2 months ago
Agora Apartments
ISSA Lesvos

ISSA Lesvos

10/10 Excellent
"I arrived for a short trip to ISSA and it was a real memorable experience. the room super clean, very supportive check in and the front office team (all of them) are extremly friendly and helpful. I loved their special care and attention during my short visit. I'd always come back...."
Violeta 1-night trip
Posted 6 months ago
ISSA Lesvos

More cheap stays in Mytilene

Porto Lesvos

Porto Lesvos

21 Komninaki str Lesvos Lesvos
Get rates
8.6/10 Excellent! (25 reviews)

Frequently asked questions

Where is the best place for a stay in Mytilene?
Hotel Lesvion is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Other top choices based on traveller reviews include ISSA Lesvos and Heliotrope Hotels. See all available top hotels, or vacation rentals in Mytilene.
What are some of the best holiday rentals that Mytilene has to offer?
Lovely Place in the Heart of Lesvos: This highly rated holiday home rental in Mytilene offers a garden and free WiFi to help you feel comfortable in your new surroundings. See all vacation rentals in Mytilene.
If I need to cancel my hotel reservation in Mytilene, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mytilene.
What's the best family accommodation in Mytilene?
Heliotrope The Studios is a guesthouse with laundry facilities and free WiFi, and it's a top choice on Expedia for families. Galazio Asteri I is another good choice for your stay with the kids. Also, attractions in the area such as Vrisa Natural History Museum are fun for the whole family. Find more child-friendly accommodations in Mytilene.
What's the best dog-friendly hotel in Mytilene?
Theofilos Paradise Boutique Hotel is a top hotel for people travelling with their pets, and offers a full-service spa and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Heliotrope Hotels and Heliotrope The Studios. See more pet-friendly hotel accommodations in Mytilene.
What's the best place to stay to stay near the beach in Mytilene?
Mythical Coast Wellness Retreat is a top beachfront hotel with 3 indoor pools and 5 restaurants, and it's located close to Kochylia . Other good choices for your stay near the beach include Heliotrope Hotels and Elysion Hotel. See more stays near the beach in Mytilene.
What's the best high-end hotel in Mytilene?
Mythical Coast Wellness Retreat is a luxury hotel with 5 restaurants and 5 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Theofilos Paradise Boutique Hotel and Elysion Hotel are two other upscale options for your stay. Find more luxury hotels in Mytilene.
What's the best boutique-style accommodation in Mytilene?
Theofilos Paradise Boutique Hotel is a favourite hotel with our travellers looking for stylish accommodation, and features 24 guestrooms, a full-service spa and a seasonal outdoor pool. See all boutique hotels in Mytilene.
What are some accommodation options with pools in Mytilene?
Theofilos Paradise Boutique Hotel: Features a children's pool, a seasonal outdoor pool and a full-service spa. Mythical Coast Wellness Retreat and Heliotrope Hotels are two additional hotels with an on-site pool. View all hotels with pools in Mytilene.
What is the best spa hotel in Mytilene?
Mythical Coast Wellness Retreat is a top beach spa hotel featuring 5 restaurants, 5 bars, 3 indoor pools and 5 cafes. Treat yourself to a facial, body scrub or Swedish massage at Mythical Coast Spa. Another popular spa hotel in Mytilene is Theofilos Paradise Boutique Hotel. See all spa hotels in Mytilene.
How is it staying in Mytilene?
Visitors to Mytilene will definitely enjoy the seaside. Tourists can also enjoy the city's museums, monuments and churches. In Mytilene, there are 82 hotels and other accommodation options to choose from. Find out more about Mytilene.
What is there to see in Mytilene?
Cultural venues include Museum of the Memorial of the Refugees of 1922, Ecclesiastical Byzantine Museum and Theriade Library and Museum of Modern Art. Landmarks like Mytilini Castle, Roman Aqueduct at Moria and Church of Agios Therapon might be worth a visit. The picturesque setting of Thermi Beach and Thermes Gera Hot Springs exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Mytilene guide.
What's the weather like in Mytilene?
The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Mytilene is 873 mm.