A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Check availability on Mytilene Spa Hotels

Our top choices for Mytilene hotels with a spa

Sauna, steam room, body treatments, hydrotherapy, aromatherapy

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
5.0 star property
Lesvos
8.8 out of 10, Excellent, (51 reviews)
  • cleanliness
    Relax in a coastal spa haven with hydrotherapy, hot springs, and three indoor pools for ultimate rejuvenation.
The price is ฿4,709
฿5,729 total
includes taxes & fees
27 Jul - 28 Jul
Mythical Coast Wellness Retreat
Terrace/patio

Elysion Hotel

Elysion Hotel
5.0 star property
Lesvos
9.2 out of 10, Wonderful, (48 reviews)
  • cleanliness
    Immerse in a rejuvenating Greek island escape with tennis courts, seasonal pools, and serene balconied rooms overlooking Lesvos.
The price is ฿5,767
฿7,837 total
includes taxes & fees
17 Jul - 18 Jul
Elysion Hotel
Turkish bath/hammam, 1 treatment room, massages

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (164 reviews)
  • cleanliness
    Escape to a boutique spa retreat with hot springs and massage therapy in the heart of Mytilene.
The price is ฿5,547
฿6,457 total
includes taxes & fees
26 Jul - 27 Jul
Theofilos Paradise Boutique Hotel
Exterior

Elies Residences

Elies Residences
Lesvos
9.8 out of 10, Exceptional, (36 reviews)
  • cleanliness
    Relax in premium villas with spa treatments and outdoor pool in this serene getaway.
The price is ฿8,118
฿8,969 total
includes taxes & fees
23 Jul - 24 Jul
Elies Residences
Deluxe Double Room, Balcony | Terrace/patio

Olive Green Studios and Apartments

Olive Green Studios and Apartments
Lesvos
10.0 out of 10, Exceptional, (4 reviews)
  • cleanliness
    Rejuvenating seaside retreat offers in-room massages and a tranquil garden sanctuary, perfect for a wellness escape by the beach.
The price is ฿5,131
฿5,697 total
includes taxes & fees
29 Jul - 30 Jul
Olive Green Studios and Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Mytilene

Pool
Breakfast included

Top Mytilene Hotel Reviews

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

10/10 Excellent
"Breakfast varied each morning and was delicious. All staff are very frieny and helpful. Property and rooms were clean and comfortable. Pool is seasonal though so plan accordingly."
Kirsten 12-night trip
Posted 2 months ago
Theofilos Paradise Boutique Hotel

Frequently asked questions

Looking to holiday at a spa hotel in Mytilene?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Discover the museums and churches in Mytilene—your cultural tour starts here. Enjoy the architecture and sea views during your holiday. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Mytilene?
Mythical Coast Wellness Retreat is a top beach spa hotel featuring 5 restaurants, 5 bars, 3 indoor pools and 5 cafes. Treat yourself to a facial, body scrub or Swedish massage at Mythical Coast Spa. Another popular spa hotel in Mytilene is Theofilos Paradise Boutique Hotel.
How many spa hotels are there in Mytilene?
Among Expedia's 86 accommodation options in Mytilene, there are 2 spa hotels.
What's there to see and do in Mytilene?
When you're in Mytilene, enjoy exploring the sights and attractions here including Port of Mytilene, Mytilini Castle and Teriade Museum. If you have a bit of extra time while you're in the area, you might want to check out Roman Aqueduct at Moria and Museum of the Memorial of the Refugees of 1922.
What is a Mytilene spa hotel?
Spa hotels in Mytilene feature full on-site spas offering services including couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.