The Best Hotels Closest to Mayo Clinic Hospital - Saint Marys Campus in Rochester - 2026 Updated Prices

An aerial view of a campus with multiple buildings, parking lots, and surrounding greenery.

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern lounge area with a sofa, chairs, and tables.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

howard

฿4,258

฿4,902 total

includes taxes & fees

24 Oct - 25 Oct

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern interior with a large dining table, sofas, and a kitchen area.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

2. The Berkman

Folwell, 0.1 km from Mayo Clinic Hospital - Saint Marys Campus

Suzette

฿5,021

฿5,838 total

includes taxes & fees

3 Nov - 4 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 0.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jon

฿3,752

฿4,319 total

includes taxes & fees

17 Oct - 18 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern lounge area with seating, a fireplace, and a bar area.

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

Chee

฿4,437

฿5,109 total

includes taxes & fees

17 Oct - 18 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 1 km from Mayo Clinic Hospital - Saint Marys Campus

Hafsa

฿4,606

฿5,302 total

includes taxes & fees

17 Oct - 18 Oct

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

A modern hotel lobby with a curved staircase, seating areas, and large windows.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

6. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Raymond

฿5,977

฿6,881 total

includes taxes & fees

7 Nov - 8 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

Rici

฿3,970

฿5,025 total

includes taxes & fees

6 Nov - 7 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

Sheri

฿3,832

฿4,479 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

A gym with exercise equipment, a clock, and a window with blinds.

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Lin

฿3,975

฿4,576 total

includes taxes & fees

7 Nov - 8 Nov

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

MATTHEW

฿3,800

฿4,375 total

includes taxes & fees

6 Nov - 7 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

Two armchairs with striped pillows, a small round table, a clock, and a phone on a counter.

A hotel gym with treadmills, elliptical machines, and free weights.

A hotel lobby with a reception desk, seating area, and a large window.

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Sean

฿3,900

฿4,489 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern bar area with seating and a counter.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern indoor pool area with lounge chairs and a pool.

12. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Lucy

฿3,967

฿4,567 total

includes taxes & fees

17 Oct - 18 Oct

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

A multi-story building with the sign 'Broadway Plaza' indicating a commercial or hotel property.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

13. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Danny

฿5,686

฿6,546 total

includes taxes & fees

17 Oct - 18 Oct

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

14. Hampton Inn Rochester-South

3.1 km from Mayo Clinic Hospital - Saint Marys Campus

dennis

฿3,686

฿4,244 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

15. Aspen Suites

0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Dana

฿4,508

฿5,450 total

includes taxes & fees

23 Oct - 24 Oct

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

16. Brentwood Inn & Suites

Downtown Rochester, 1.3 km from Mayo Clinic Hospital - Saint Marys Campus

Daniel

฿3,154

฿3,631 total

includes taxes & fees

29 Oct - 30 Oct

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

17. Quality Inn & Suites Mayo Clinic Area

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jessica

฿2,553

฿2,976 total

includes taxes & fees

1 Nov - 2 Nov

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A reception area with two counters, a patterned wall, and a wooden floor.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

18. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Richard

฿3,972

฿4,573 total

includes taxes & fees

23 Oct - 24 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A restaurant interior with wooden tables, chairs, and a stone wall.

19. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1.2 km from Mayo Clinic Hospital - Saint Marys Campus

Christine

฿3,626

฿4,174 total

includes taxes & fees

17 Oct - 18 Oct

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A hotel reception desk with a modern design, a clock, and a digital screen.

A modern conference room with a long table, multiple chairs, and a wooden partition.

A modern lounge area with a curved sofa, a round table, and a seating area with chairs.

20. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park, 0.3 km from Mayo Clinic Hospital - Saint Marys Campus

Jackie

฿3,449

฿3,971 total

includes taxes & fees

17 Oct - 18 Oct

View all properties

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Property	Property class	Guest rating
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,000 reviews	View
The Berkman	9.6 Exceptional 447 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 742 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 312 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 565 reviews	View

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent

"Easy access to Mayo with parking onsite and a free hot breakfast. Loved the kitchenette in the rooms as well."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"I use this hotel when I have appointments at Mayo. It is so convenient with the subway level. Everything is connected. Hotel room is nice. Parking is a little hard. We use their parking lot and pay the $15. The complimentary breakfast has a great variety of items to choose from."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"Great location! Nice place to stay. Please just pay a little extra and buy 2 ply toilet paper"

Kahler Grand Hotel

10/10 Excellent

"Best price and location with options for parking."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Great location. Great accommodations. Highly recommended."

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The room was very clean. Staff were kind and pleasant upon check in."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Absolutely perfect hotel, especially if you are traveling back and forth to St. Mary’s campus for Mayo. Great breakfast, free laundry, great shower, comfy bed. Best you could get in these circumstances away from home. Thank you!"

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

10/10 Excellent

"Clean room. Good breakfast."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Staff was good, rooms were clean but needing some updates"

Frequently asked questions

What's the area like around Mayo Clinic Hospital - Saint Marys Campus?

Mayo Clinic Hospital - Saint Marys Campus is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 123 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Mayo Clinic Hospital - Saint Marys Campus?

Adjacent to Mayo Clinic Hospital - Saint Marys Campus, The Berkman is one of the top choices for your stay based on our traveller data, and this aparthotel offers in-room kitchens and a fitness centre. Other good options within a short distance include Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area.

How many hotels are there close to Mayo Clinic Hospital - Saint Marys Campus?

Expedia has 123 hotels and other accommodation options within a mile from Mayo Clinic Hospital - Saint Marys Campus.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Hospital - Saint Marys Campus, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best options available near Mayo Clinic Hospital - Saint Marys Campus.

What can I see and do near Mayo Clinic Hospital - Saint Marys Campus?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Sights like Assisi Heights and Plummer House highlight some of the local culture. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Search Hotels Near Mayo Clinic Hospital - Saint Marys Campus, Rochester

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2. The Berkman

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. Hilton Rochester Mayo Clinic Area

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Hyatt House Rochester/Mayo Clinic Area

13. Broadway Plaza, Trademark Collection by Wyndham

14. Hampton Inn Rochester-South

15. Aspen Suites

16. Brentwood Inn & Suites

17. Quality Inn & Suites Mayo Clinic Area

18. Hilton Garden Inn Rochester Downtown, MN

19. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

20. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

AmericInn by Wyndham Rochester Near Mayo Clinic

Kahler Grand Hotel

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Frequently asked questions