Main Street
Visit Main Street
Tours & day trips
See all 21 activities
Best of Martha's Vineyard 3 hour Full-Island Tour
Activity duration is 3 hours
9.4 out of 10 with 58 reviews
Free cancellation available
Water activities
See all 4 activities
Cape Cod Explorer Tour
Activity duration is 2 hours
10.0 out of 10 with 3 reviews
Free cancellation available
Food, drink & nightlife
See all 3 activities
Hyannis: Hyannis Harbour Sunset Cruise
Activity duration is 1 hour and 15 minutes
7.4 out of 10 with 11 reviews
Free cancellation available
Adventure & outdoor
See all 3 activities
Hyannis: 3 Hour Family Fishing Special - Helen H Fishing
Activity duration is 3 hours
10.0 out of 10 with 4 reviews
Free cancellation available
Top Hotel Deals
Check availability on hotels close to Main Street
Margaritaville Resort Cape Cod
1225 Iyannough Rd Hyannis MA
Craigville Beach Inn
1338 Craigville Beach Rd Centerville MA
The Ocean View
966 Craigville Beach Road Centerville MA
Hyannis Plaza Hotel
662 Main Street Hyannis MA
Hyannis Harbor Hotel
213 Ocean St Hyannis MA
Bayside Resort Hotel
225 Route 28 West Yarmouth MA
Hyannis Travel Inn
18 North St Hyannis MA
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
540 Old Colony Rd Hyannis MA
Cape Sands Inn
149 Main St - RT 28 West Yarmouth MA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.