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Our top choices for Main Street hotels

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1,003 reviews)
"Very nice stay"
United States
Robert
The price is ฿3,766
฿5,222 total
includes taxes & fees
11 Mar - 12 Mar
Anchor In Distinctive Waterfront Lodging

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
9.1 km from Main Street
8.8 out of 10, Excellent, (682 reviews)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is ฿4,112
฿4,706 total
includes taxes & fees
2 Apr - 3 Apr
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Sea Street Inn

Sea Street Inn
4.0 star property
8 km from Main Street
9.8 out of 10, Exceptional, (45 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is ฿7,697
฿8,810 total
includes taxes & fees
10 Mar - 11 Mar
Sea Street Inn

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (494 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is ฿4,340
฿4,967 total
includes taxes & fees
15 Mar - 16 Mar
Courtyard By Marriott Cape Cod Hyannis

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (994 reviews)
"Great place to stay "
United States
Lilian
The price is ฿3,634
฿4,159 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Hyannis by IHG

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.0 out of 10, Very good, (1,006 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is ฿2,995
฿3,428 total
includes taxes & fees
1 Apr - 2 Apr
Comfort Inn Hyannis - Cape Cod

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1,001 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is ฿3,783
฿4,329 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Cape Cod-West Yarmouth

Courtyard Resort

Courtyard Resort
2.0 star property
8.8 km from Main Street
8.2 out of 10, Very good, (64 reviews)
"Great stay staff was awesome. The room was clean and reasonably priced!"
United States
Michael
The price is ฿3,474
฿3,976 total
includes taxes & fees
10 Mar - 11 Mar
Courtyard Resort

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
8.8 km from Main Street
7.4 out of 10, Good, (1,006 reviews)
"Room was clean and what we needed. Very comfortable. Breakfast options were nice. Pancakes, scrambled eggs, potatoes and a variety of yogurt among a few other danishes. Enjoyed our stay. "
United States
Matthew
The price is ฿3,124
฿3,940 total
includes taxes & fees
15 Mar - 16 Mar
Cape Cod Hotel

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
10.9 km from Main Street
9.2 out of 10, Wonderful, (116 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is ฿3,751
฿4,444 total
includes taxes & fees
11 Mar - 12 Mar
Uncommoner Hotel by Reverie Boutique Collection

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
8.7 km from Main Street
8.6 out of 10, Excellent, (477 reviews)
"The interior of the rooms were clean, the staff was friendly. "
United States
Maria Luisa
The price is ฿3,994
฿6,395 total
includes taxes & fees
16 Mar - 17 Mar
Margaritaville Resort Cape Cod

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
11.2 km from Main Street
8.8 out of 10, Excellent, (1,552 reviews)
"The place was clean, staff very nice and a good breakfast! Nice pool and beach area."
United States
LisaAnn
The price is ฿2,980
฿3,776 total
includes taxes & fees
12 Mar - 13 Mar
Bayside Resort Hotel

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (894 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is ฿4,040
฿4,624 total
includes taxes & fees
5 Apr - 6 Apr
Doubletree by Hilton Cape Cod - Hyannis

Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1,026 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is ฿2,377
฿2,720 total
includes taxes & fees
10 Mar - 11 Mar
Cape Sands Inn

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
11.2 km from Main Street
9.2 out of 10, Wonderful, (254 reviews)
"Was unaware that pool facilities were closed for 2 weeks of maintenance which was primary purpose of stay"
United States
Edward
The price is ฿3,641
฿4,167 total
includes taxes & fees
10 Mar - 11 Mar
The Cove at Yarmouth by Westgate Resorts

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
9.1 km from Main Street
8.0 out of 10, Very good, (1,004 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is ฿3,983
฿5,845 total
includes taxes & fees
10 Mar - 11 Mar
Hyannis Harbor Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
9.3 km from Main Street
8.4 out of 10, Very good, (20 reviews)
"It was ok staff was nice"
United States
Troy
The price is ฿3,766
฿4,310 total
includes taxes & fees
29 Mar - 30 Mar
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
12.4 km from Main Street
8.0 out of 10, Very good, (1,006 reviews)
"Great place "
United States
Lilian
The price is ฿2,907
฿3,327 total
includes taxes & fees
10 Mar - 11 Mar
Aiden by Best Western Cape Cod - West Yarmouth

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
7.9 km from Main Street
7.8 out of 10, Good, (194 reviews)
"Nice place to stay "
United States
Kevin
The price is ฿2,135
฿2,444 total
includes taxes & fees
6 Apr - 7 Apr
Sea Breeze Inn

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
8.2 km from Main Street
7.0 out of 10, Good, (1,007 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is ฿2,821
฿3,547 total
includes taxes & fees
10 Mar - 11 Mar
Hyannis Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street Hotel Reviews

Hotels near other Main Street attractions

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, take a look at the 25 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Another good choice is The Ocean View, located 2.6 mi (4.3 km) away.
How many hotels will I be able to find near Main Street?
Expedia has 25 hotels and other accommodation options within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best options available near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art or Toad Hall Classic Sports Car Museum. You can enjoy live performances at Cotuit Center for the Arts and Cape Cod Melody Tent. Dip your toes in the water at Craigville Beach, Dowses Beach and Long Beach.