The Best Hotels in Mackenzie, St. Louis - 2026 Updated Prices

A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.

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Our top choices for Mackenzie hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 6.2 km from Mackenzie

Jennifer

฿5,456 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

2. SpringHill Suites St. Louis Brentwood

4.9 km from Mackenzie

Cheryl

฿4,545 total

includes taxes & fees

11 Oct - 12 Oct

A lobby with a reception desk, seating area, and a bicycle in the background.

3. Drury Inn & Suites St. Louis Forest Park

4.7 km from Mackenzie

Robert

฿5,816 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a fire pit, seating, and a building in the background.

4. Courtyard by Marriott St. Louis Brentwood

5.5 km from Mackenzie

Aaron

฿4,644 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop terrace with wicker furniture, offering a city view.

5. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 12.1 km from Mackenzie

Salvatore

฿5,270 total

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

6. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

11.2 km from Mackenzie

Thomas

฿4,799 total

includes taxes & fees

4 Oct - 5 Oct

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

7. River City Casino & Hotel

7.3 km from Mackenzie

Ashley

฿4,261 total

includes taxes & fees

15 Oct - 16 Oct

The Clayton Plaza Hotel sign with a stone wall and plants in front.

8. Clayton Plaza Hotel & Extended Stay

7.8 km from Mackenzie

Sivakumar

฿3,605 total

includes taxes & fees

11 Oct - 12 Oct

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

9. The Cheshire

5.9 km from Mackenzie

Matthew

฿5,883 total

includes taxes & fees

11 Oct - 12 Oct

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

10. La Quinta Inn & Suites by Wyndham St Louis Route 66

8.3 km from Mackenzie

Crystal

฿4,123 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

11. Hampton Inn & Suites St. Louis/South I-55

11.2 km from Mackenzie

Shannon

฿4,061 total

includes taxes & fees

18 Oct - 19 Oct

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

12. Live by Loews - St.Louis

Downtown St. Louis, 11.7 km from Mackenzie

Frank

฿6,313 total

includes taxes & fees

4 Oct - 5 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

13. Drury Plaza Hotel St. Louis Brentwood

5.8 km from Mackenzie

Janell

฿5,390 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

14. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 7.4 km from Mackenzie

paullita jeanne

฿6,070 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop restaurant with round tables, chairs, and a view of the city.

15. Moonrise Hotel

8.4 km from Mackenzie

Nicole

฿5,241 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

16. Pear Tree Inn St. Louis Airport

18.2 km from Mackenzie

Murphy

฿3,537 total

includes taxes & fees

4 Oct - 5 Oct

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

17. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 10.5 km from Mackenzie

James

฿4,976 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

18. Best Western Plus Fenton

12.2 km from Mackenzie

Evelyn

฿3,737 total

includes taxes & fees

29 Sept - 30 Sept

A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

19. Holiday Inn St Louis SW - Route 66 by IHG

8.5 km from Mackenzie

Arnaud

฿4,686 total

includes taxes & fees

4 Oct - 5 Oct

A modern lobby with a stone fireplace, blue sofas, and potted plants.

20. Comfort Suites St. Louis - Sunset Hills

8.4 km from Mackenzie

John

฿4,585 total

includes taxes & fees

5 Oct - 6 Oct

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Where to stay in Mackenzie

Find the best Mackenzie areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch National Park to Kiener Plaza – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A fountain in front of a red brick building with green roofs and white trim.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Mackenzie Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"I would go back and stay again because the overall experience was good."

21C Museum Hotel St Louis

10/10 Excellent

"Such a cool and trendy boutique hotel with all the amenities. Beautiful building. Paid parking around d the corner. 20 minutes walk to the Gateway Arch. So nice to get back to the hotel in the evening, have a few drinks at the bar and finish the evening with a visit to the pool area with hot tub, sauna, and steam room as well as the lap pool. Staff were incredible, so friendly and knowledgeable. Kristos and all the other bartenders were super friendly and made us some great cocktails. Would definitely recommend to friends and family and would stay again if we were back in the area."

Live by Loews - St.Louis

10/10 Excellent

"Wonderful stay. Comfy bed. One of cleanest rooms I’ve ever stayed in. It is convenient to Busch Stadium, but just a heads up that if you stay there, any of the events may be cause for a bit of noise - but with the television on, it just sounded like any metropolitan area. Would not hesitate to stay again."

Frequently asked questions

What's it like in Mackenzie?

Travellers will be sure to find plenty to entertain them in St. Louis's Mackenzie neighbourhood.

If I need to cancel my hotel reservation in Mackenzie, will I receive a refund?

Yes, the majority of room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Mackenzie.

What is there to do in this St. Louis neighbourhood?

Lindenwood Park, Repertory Theatre of St. Louis and River des Peres Greenway Trailhead are just a few of the places to visit in and around Mackenzie. While you're out sightseeing, The Focal Point and Webster Groves Tennis Center are a couple of additional sights to visit in St. Louis.

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Our top choices for Mackenzie hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. SpringHill Suites St. Louis Brentwood

3. Drury Inn & Suites St. Louis Forest Park

4. Courtyard by Marriott St. Louis Brentwood

5. Drury Plaza Hotel St. Louis at the Arch

6. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

7. River City Casino & Hotel

8. Clayton Plaza Hotel & Extended Stay

9. The Cheshire

10. La Quinta Inn & Suites by Wyndham St Louis Route 66

11. Hampton Inn & Suites St. Louis/South I-55

12. Live by Loews - St.Louis

13. Drury Plaza Hotel St. Louis Brentwood

14. Home2 Suites by Hilton St. Louis/Forest Park

15. Moonrise Hotel

16. Pear Tree Inn St. Louis Airport

17. Fairfield Inn & Suites by Marriott St. Louis Downtown

18. Best Western Plus Fenton

19. Holiday Inn St Louis SW - Route 66 by IHG

20. Comfort Suites St. Louis - Sunset Hills

Where to stay in Mackenzie

Downtown St. Louis

Clayton

Central West End

St. Charles Historic District

Creve Coeur

Top Mackenzie Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Frequently asked questions

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