The Best Hotels Closest to Lewis and Clark Interpretive Center in St. Louis - 2026 Updated Prices

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Our top choices for Lewis and Clark Interpretive Center hotels

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A spacious dining area with high tables and booths, large windows, and a view of greenery outside.

A hotel room with a large bed, two bedside tables, a desk, and a chair.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

1. Comfort Inn Edwardsville - St. Louis

9.4 km from Lewis and Clark Interpretive Center

Linda

฿3,153

฿3,625 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a stone fireplace, a reception desk, and a large window.

A modern lobby with a blue sofa, a white coffee table, and a reception desk in the background.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and tables, large windows with a view of trees, and a tiled floor.

2. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

6.2 km from Lewis and Clark Interpretive Center

Sabra

฿3,696

฿4,102 total

includes taxes & fees

19 Oct - 20 Oct

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

A lobby with a sofa, armchairs, a chandelier, decorative mirrors, and a fireplace.

A hotel dining area with tables and chairs, a kitchen in the background, and large windows with curtains.

A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

3. Holiday Inn Express & Suites Edwardsville by IHG

10.9 km from Lewis and Clark Interpretive Center

Mary

฿4,339

฿4,989 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

A restaurant with a brick wall, large windows, and a seating area with tables and chairs.

4. Drury Inn & Suites St. Louis Collinsville

15.4 km from Lewis and Clark Interpretive Center

Lisa

฿3,676

฿4,227 total

includes taxes & fees

27 Sept - 28 Sept

A brick building with a wooden gazebo in front.

A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.

A hotel room with two beds, a dresser, a television, and a bathroom visible through an open door.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

5. Country Hearth Inn & Suites Edwardsville St. Louis

10.8 km from Lewis and Clark Interpretive Center

les

฿4,273

฿4,913 total

includes taxes & fees

24 Sept - 25 Sept

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.

A long, straight corridor with a series of doors on one side and a black railing on the other.

A reception desk with a 'NO Pets Allowed' sign, a 'Please ring door bell' sign, and a window with a view of a parking lot.

6. Bel Air Motel

6.3 km from Lewis and Clark Interpretive Center

Tai

฿2,111

฿2,641 total

includes taxes & fees

27 Sept - 28 Sept

7. Hampton Inn & Suites St. Louis/Alton

14 km from Lewis and Clark Interpretive Center

Kathy

฿4,318

฿4,922 total

includes taxes & fees

4 Oct - 5 Oct

A cozy lounge area with leather seating, a wooden coffee table, and a fireplace.

A hotel room with a bed, a sofa, a desk, and a chair.

A hotel bathroom with a large bathtub, a sofa, a microwave, and a desk with a lamp.

A hotel lobby with a beverage fridge, a television, and a seating area with a sofa and armchairs.

8. Best Western Plus Pontoon Beach

6.8 km from Lewis and Clark Interpretive Center

Timothy

฿3,428

฿3,804 total

includes taxes & fees

27 Sept - 28 Sept

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A reception desk with a wooden counter, two HP laptops, a telephone, and a framed black and white photo on the wall.

A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

9. Super 8 by Wyndham Troy IL/St. Louis Area

17.8 km from Lewis and Clark Interpretive Center

Esmeralda

฿2,252

฿2,500 total

includes taxes & fees

8 Oct - 9 Oct

A spacious dining area with high ceilings, multiple dining tables, and chairs.

A hotel room with a sofa, two chairs, a table, and a flat-screen TV mounted on the wall.

A large indoor pool with clear blue water, surrounded by blue walls and windows.

A Hampton Inn & Suites with a clear entrance, a parking lot, and a flagpole.

10. Hampton Inn & Suites St. Louis-Edwardsville

10.1 km from Lewis and Clark Interpretive Center

Tashae

฿3,506

฿3,926 total

includes taxes & fees

19 Oct - 20 Oct

A buffet area with a wooden counter, various food items, and a coffee station.

A hotel room with a sofa, a small table, a lamp, and a TV.

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

A hotel room with two beds, a sofa, a desk, and a window with curtains.

11. Comfort Inn Collinsville near St. Louis

15.3 km from Lewis and Clark Interpretive Center

Jose Rene

฿3,524

฿4,052 total

includes taxes & fees

19 Oct - 20 Oct

A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

A spacious interior with a high ceiling, a staircase with wooden balusters, and a modern kitchen area in the background.

A modern room with a stone wall, a flat-screen TV, two red chairs, a small table, and a view of the outside.

12. Red Lion Inn & Suites Pontoon Beach

5.6 km from Lewis and Clark Interpretive Center

Jennifer

฿2,385

฿2,700 total

includes taxes & fees

24 Sept - 25 Sept

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and a landscaped area with trees.

A modern indoor space with a long white table, blue and orange chairs, a sofa with patterned cushions, and a coffee station.

Two reception desks with a modern design, a blue geometric wall in the background, and a sign indicating the hotel name.

A modern hotel corridor with a wooden reception desk, a staircase, and a snack bar with various packaged foods.

13. Holiday Inn Express and Suites Alton St Louis Area by IHG

13.8 km from Lewis and Clark Interpretive Center

Chris

฿4,206

฿4,794 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with two beds, a desk, a mirror, and a television.

A laundry room with two washing machines, a drying rack, and instructional posters on the wall.

A swimming pool with a clear blue water, surrounded by lounge chairs and a sunbed.

A hotel lobby with a reception desk, a coffee station, and a seating area.

14. Red Roof Inn St Louis - Troy, IL

18 km from Lewis and Clark Interpretive Center

crystal

฿2,146

฿2,382 total

includes taxes & fees

30 Sept - 1 Oct

An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.

A parking area with electric vehicle charging stations, marked parking spaces, and a chain-link fence.

A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.

A hotel with a prominent sign reading 'The Great Rivers Ascend Collection By Choice Hotels.'

15. The Great Rivers, an Ascend Collection Hotel

11.5 km from Lewis and Clark Interpretive Center

Elizabeth

฿2,872

฿3,273 total

includes taxes & fees

30 Sept - 1 Oct

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

A breakfast bar with a microwave, coffee makers, and a fruit display.

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A hotel with a central entrance, multiple floors, and a clear sky.

16. La Quinta Inn & Suites by Wyndham Pontoon Beach

6.9 km from Lewis and Clark Interpretive Center

Weldon

฿3,610

฿4,151 total

includes taxes & fees

24 Sept - 25 Sept

A hotel lobby with a stone fireplace, a dining area with tables and chairs, and a colorful carpet.

A vending machine with snacks and drinks, a microwave, and a refrigerator.

A gym with exercise equipment, a bench, and a rack of dumbbells.

A modern lobby with a stone accent wall, a blue sofa, and a reception desk.

17. Fairfield Inn by Marriott St. Louis Collinsville, IL

15.3 km from Lewis and Clark Interpretive Center

David A.

฿3,428

฿3,942 total

includes taxes & fees

19 Oct - 20 Oct

A hotel entrance with a covered driveway and a parking area.

A hotel room with two beds, a TV, a desk, and a chair.

A hotel room with two desks, each with a computer, a lamp, and a chair.

A hotel lobby with striped armchairs, a round coffee table, a sofa, and a clock on the wall.

18. Best Western Plus Parkway Hotel

13.9 km from Lewis and Clark Interpretive Center

Steve

฿2,717

฿3,096 total

includes taxes & fees

1 Oct - 2 Oct

A hotel room with a bed, a framed cityscape picture, and a view of a cityscape through a window.

A bathroom with a shower curtain, a bathtub, and a microwave.

A parking lot with a motel building in the background.

A compact room with a kitchenette, a flat-screen TV mounted above the microwave, a small refrigerator, a wooden dresser, and a door leading to a closet with hanging clothes.

19. Indian Mound Motel

16.7 km from Lewis and Clark Interpretive Center

paul

฿1,275

฿2,188 total

includes taxes & fees

24 Sept - 25 Sept

A modern kitchen with marble countertops, a built-in coffee station, and a seating area with metal chairs and tables.

A bathroom with a bathtub, toilet, and a towel rack.

A hotel room with a large bed, a nightstand with a phone, and wall-mounted lights.

A motel with multiple floors, a parking lot, and a clear sky.

20. Days Inn by Wyndham Troy IL

18 km from Lewis and Clark Interpretive Center

฿2,477

฿2,749 total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Compare popular hotels close to Lewis and Clark Interpretive Center

Property	Property class	Guest rating
Comfort Inn Edwardsville - St. Louis	8.4 Very good 947 reviews	View
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City	9.2 Wonderful 528 reviews	View
Holiday Inn Express & Suites Edwardsville by IHG	9.2 Wonderful 910 reviews	View
Drury Inn & Suites St. Louis Collinsville	9.6 Exceptional 1,005 reviews	View
Country Hearth Inn & Suites Edwardsville St. Louis	8.6 Excellent 751 reviews	View

Top Lewis and Clark Interpretive Center Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Great happy hour and breakfast."

Live by Loews - St.Louis

10/10 Excellent

"Awesome stay for Bananas game. Got to meet several players in the lobby including Cardinals WS MVP, David Eckstein. Great place to stay. Will be back. Wagyu burger in the bar was good too."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Very pleasant and helpful staff."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Our room was clean and wonderful. The front desk staff were friendly & helpful. The hot breakfast was great and very much appreciated. Parking was excellent."

Super 8 by Wyndham St. Louis North

8/10 Good

"It was fine. But not I a real safe neighbor hood"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"This was a great place with a welcoming atmosphere. The staff were outstanding—friendly, attentive, and professional—making the experience even more enjoyable. The people there were remarkable, contributing to a lively and positive environment."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Great stay!! Was near the arch and stadium!"

Marriott St. Louis Grand

10/10 Excellent

"Amazing stay staff was unbelievable"

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.

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Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.

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Hartford Park

After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments.

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Hartford City Hall

Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums.

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Jones-Confluence Point State Park

You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area.

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Dads Club Park

Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana.

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South Roxana Dad's Club Park

South Roxana Dad's Club Park is just one of the places to see in South Roxana, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?

Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travellers like for its sporting events. You'll find 12 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to Lewis and Clark Interpretive Center?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 13 mi (20.9 km) from Lewis and Clark Interpretive Center. Other good options around the area include Super 8 by Wyndham St. Louis North and Drury Plaza Hotel St. Louis at the Arch.

How many hotels will I find close to Lewis and Clark Interpretive Center?

Expedia has 12 hotels and other accommodation options a few miles from Lewis and Clark Interpretive Center.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Lewis and Clark Interpretive Center.

What can I see and do near Lewis and Clark Interpretive Center?

You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.

Search Hotels Near Lewis and Clark Interpretive Center, St. Louis

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Our top choices for Lewis and Clark Interpretive Center hotels

1. Comfort Inn Edwardsville - St. Louis

2. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

3. Holiday Inn Express & Suites Edwardsville by IHG

4. Drury Inn & Suites St. Louis Collinsville

5. Country Hearth Inn & Suites Edwardsville St. Louis

6. Bel Air Motel

7. Hampton Inn & Suites St. Louis/Alton

8. Best Western Plus Pontoon Beach

9. Super 8 by Wyndham Troy IL/St. Louis Area

10. Hampton Inn & Suites St. Louis-Edwardsville

11. Comfort Inn Collinsville near St. Louis

12. Red Lion Inn & Suites Pontoon Beach

13. Holiday Inn Express and Suites Alton St Louis Area by IHG

14. Red Roof Inn St Louis - Troy, IL

15. The Great Rivers, an Ascend Collection Hotel

16. La Quinta Inn & Suites by Wyndham Pontoon Beach

17. Fairfield Inn by Marriott St. Louis Collinsville, IL

18. Best Western Plus Parkway Hotel

19. Indian Mound Motel

20. Days Inn by Wyndham Troy IL

Compare popular hotels close to Lewis and Clark Interpretive Center

Top Lewis and Clark Interpretive Center Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Live by Loews - St.Louis

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Airport

Super 8 by Wyndham St. Louis North

Renaissance St. Louis Airport Hotel

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Marriott St. Louis Grand

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Lewis and Clark State Memorial Park

Hartford Park

Hartford City Hall

Jones-Confluence Point State Park

Dads Club Park

South Roxana Dad's Club Park

Frequently asked questions