A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo Luxury Hotels

Tonight
30 Aug - 31 Aug
Tomorrow
31 Aug - 1 Sep
Next weekend
4 Sep - 6 Sep
In two weeks
11 Sep - 13 Sep

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
฿8,443
฿11,324 total
includes taxes & fees
13 Sept - 14 Sept
Playa Largo Resort & Spa, Autograph Collection

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
฿7,847
฿10,653 total
includes taxes & fees
28 Sept - 29 Sept
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
฿7,251
฿9,482 total
includes taxes & fees
31 Aug - 1 Sept
Reefhouse Resort & Marina

4. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
฿4,934
฿7,972 total
includes taxes & fees
7 Sept - 8 Sept
Cheeca Lodge & Spa

5. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
฿5,801
฿8,948 total
includes taxes & fees
7 Sept - 8 Sept
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

6. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
฿4,895
฿7,928 total
includes taxes & fees
2 Sept - 3 Sept
Amara Cay Resort

7. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
฿8,079
฿11,324 total
includes taxes & fees
22 Sept - 23 Sept
Islander Resort

8. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
฿4,448
฿7,425 total
includes taxes & fees
1 Sept - 2 Sept
La Siesta Resort & Villas

9. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
฿11,920
฿15,474 total
includes taxes & fees
31 Aug - 1 Sept
The Islands of Islamorada

10. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
฿4,801
฿10,672 total
includes taxes & fees
31 Aug - 1 Sept
Find Peace - Tiny House in Japanese Garden
View all properties

Top Key Largo Hotel Reviews

Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

8/10 Good
"Good"
Esther 2-night trip
Posted 2 hours ago
Marina Del Mar Resort and Marina
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Perfect little spot for a perfect little weekend in Key Largo"
Daniel 1-night trip
Posted 5 hours ago
Sunset Cove Beach Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Beach, tiki bar and pool area were a tropical paradise. Breakfast was better than some other Hampton Inns where I have stayed."
Robin 4-night trip
Posted 8 hours ago
Hampton Inn Key Largo Manatee Bay
Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"Awesome ! We really enjoyed the amenities and friendly staff. What else !"
Hourad 2-night trip
Posted 10 hours ago
Reefhouse Resort & Marina
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The view from the docks at sunset was beautiful."
Kimberly 2-night trip
Posted 15 hours ago
The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great place! Close to everything in Key Largo. Staff was great. We will need to get a bigger room next time we visit. We will be back."
Charles 4-night trip
Posted 18 hours ago
Bayside Inn Key Largo
Azul del Mar

Azul del Mar

10/10 Excellent
"A amazing location with private beach swimming pool next door and restaurants nearby Ideal chill out spot"
Stephen 2-night trip
Posted 20 hours ago
Azul del Mar

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best luxury hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Another upscale choice for your holiday is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 29°C, while the coldest months are January and February, with an average of 22°C. Average annual precipitation for Key Largo is 1122 mm.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

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