Isle of Palms South Travel Guide
Jacksonville
Visit Isle of Palms South
Popular places to visit

Mayo Clinic Florida
If Mayo Clinic Florida is what brings you to town, hopefully you'll have a chance to explore more of Jacksonville.

Jacksonville Naval Air Station
After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the lively festivals or attend a sporting event in this family-friendly area.

Jacksonville Zoo and Gardens
Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.

EverBank Stadium
Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.

TPC Sawgrass
Enjoy a round of golf in Ponte Vedra Beach at TPC Sawgrass. Stroll along the area's seaside or experience its acclaimed theatre scene.

Prime F. Osborn III Convention Center
See exhibitions and join in community events at the former Union Station, a large train station which dates back to 1919.
Things to do

Airboat Adventure in Saint Augustine with a Guide

The Escape Game at St. John's Town Center in Jacksonville
Top hotels in Isle of Palms South

Margaritaville Jacksonville Beach
Courteous staff and hotel is exceptionally clean!
Reviewed on 15 Dec 2025

Hyatt Regency Jacksonville
This is a lovely hotel. The location is beautiful on the water, the restaurants and staff were awesome, the front desk was helpful and friendly and the rooms are comfortable and clean. The pet situation is great too. There is easy access to a nice grass area for the dogs too. I don’t know how we ...
Reviewed on 14 Dec 2025

DoubleTree by Hilton Hotel Jacksonville Riverfront
Clean room, friendly and very helpful staff.. spectacular view.. Ashanti was extremely helpful and very welcoming.. and we love the restaurant downstairs..literally 10 of 10 ..💯
Reviewed on 13 Dec 2025

Comfort Suites Baymeadows Near Butler Blvd
Great customer service..very clean and quiet
Reviewed on 15 Dec 2025

Southbank Hotel by Marriott Jacksonville Riverwalk
Very nice
Reviewed on 12 Dec 2025

Hilton Jacksonville At Mayo Clinic
It is a newly built hotel, so rooms wete in good condition. Staff was very friendly and respectful. Id you do not have car, it will be chellenging to go aroubd.
Reviewed on 11 Dec 2025
Check Isle of Palms South hotel availability
Other neighbourhoods around Isle of Palms South

Golden Glades - The Woods
While Golden Glades - The Woods isn't home to many top sights, St. Johns Town Center and UNF Arena are some notable places to visit nearby.

Old Ponte Vedra Beach
While visiting Old Ponte Vedra Beach, you might make a stop by sights like Ponte Vedra Beach and Mickler Beach.

Sawgrass
Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Palm Valley
If you're spending some time in Palm Valley, TPC Sawgrass and Cornerstone Park are top sights worth seeing.

Arlington
If you're spending some time in Arlington, Regency Square Mall and Jacksonville Arboretum and Gardens are top sights worth seeing.

Baymeadows
Notable for its shopping, restaurants and beaches, Baymeadows is a sought-after destination for many travellers visiting Jacksonville. If you want to see some sights in the area, check out Cinemark Tinseltown Jacksonville or St. Johns Town Center.




