Search Hotels in Isle of Palms South, Jacksonville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Isle of Palms South hotels

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms South
10.0 out of 10, Exceptional, (13 reviews)
"Clean rooms ,pet friendly,friendly staff"
United States
Theresa
The price is ฿3,819
฿4,334 total
includes taxes & fees
1 Jun - 2 Jun
Hyatt Studios Jacksonville/St Johns Town Center

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,257 reviews)
"This place is a gem. Price and comfort and an ideal location "
United States
andrew
The price is ฿1,571
฿1,783 total
includes taxes & fees
9 May - 10 May
Weekly Inn

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,009 reviews)
"Typical Holiday Inn , very nice but not over the top."
United States
Gary
The price is ฿3,512
฿3,986 total
includes taxes & fees
11 May - 12 May
Holiday Inn Express Jacksonville - Blount Island by IHG

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
21.4 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,002 reviews)
"Definitely would stay again!!"
United States
Nyasia
The price is ฿3,091
฿3,508 total
includes taxes & fees
25 May - 26 May
Tru by Hilton Jacksonville South Mandarin

Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
3.0 star property
13.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (679 reviews)
"Staff was friendly and hotel was nice as well for a last minute extension to our spring break trip!"
United States
Louie
The price is ฿3,269
฿3,711 total
includes taxes & fees
14 May - 15 May
Courtyard by Marriott Jacksonville I-295/East Beltway

Residence Inn by Marriott Jacksonville South/Bartram Park

Residence Inn by Marriott Jacksonville South/Bartram Park
3.0 star property
18.3 km from Isle of Palms South
9.2 out of 10, Wonderful, (661 reviews)
"My family and I stayed at this property recently when my daughter had to have surgery. The staff was very friendly and would say, "welcome back" each time we would return. The beds were so comfortable, our room was very clean, and quiet. We will stay again when my daughter needs to see her doctor for a follow up."
United States
Kerri
The price is ฿4,031
฿4,575 total
includes taxes & fees
14 May - 15 May
Residence Inn by Marriott Jacksonville South/Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,005 reviews)
"Clean room, friendly staff, great breakfast"
United States
Jared
The price is ฿3,269
฿3,711 total
includes taxes & fees
31 May - 1 Jun
Hampton Inn & Suites Jacksonville South - Bartram Park

Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd
2.5 star property
16.2 km from Isle of Palms South
8.2 out of 10, Very good, (1,391 reviews)
"Great location and overall bargain for the price."
United States
Eleanor
The price is ฿2,246
฿2,549 total
includes taxes & fees
19 May - 20 May
Baymont by Wyndham Jacksonville/Butler Blvd

Holiday Inn Jacksonville E 295 Baymeadows by IHG

Holiday Inn Jacksonville E 295 Baymeadows by IHG
3.0 star property
9.6 km from Isle of Palms South
8.6 out of 10, Excellent, (1,009 reviews)
"The hotel location is away from traffic "
United States
Ireneo
The price is ฿3,265
฿3,705 total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Jacksonville E 295 Baymeadows by IHG

Aloft Jacksonville Airport

Aloft Jacksonville Airport
3.0 star property
30.3 km from Isle of Palms South
8.8 out of 10, Excellent, (1,008 reviews)
"This was a very nice hotel that my family stayed at right before our cruise and I would definitely stay again"
United States
Kayley
The price is ฿3,254
฿3,694 total
includes taxes & fees
16 May - 17 May
Aloft Jacksonville Airport

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.3 km from Isle of Palms South
7.8 out of 10, Good, (1,879 reviews)
"Clean room, kind staff "
United States
Jacob
The price is ฿2,555
฿2,900 total
includes taxes & fees
27 May - 28 May
Wyndham Garden Jacksonville

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,004 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is ฿4,711
฿5,253 total
includes taxes & fees
25 May - 26 May
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.7 km from Isle of Palms South
8.8 out of 10, Excellent, (1,008 reviews)
"Great stay!"
United States
Satavia
The price is ฿3,196
฿3,628 total
includes taxes & fees
31 May - 1 Jun
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
17.7 km from Isle of Palms South
8.8 out of 10, Excellent, (1,008 reviews)
"Clean & comfortable bed!"
United States
Misty
The price is ฿3,259
฿3,699 total
includes taxes & fees
31 May - 1 Jun
Courtyard by Marriott Jacksonville Flagler Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,026 reviews)
"Nice place to stay "
United States
Rashad
The price is ฿4,318
฿4,901 total
includes taxes & fees
31 May - 1 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms, 2 km from Isle of Palms South
9.4 out of 10, Exceptional, (501 reviews)
"Great place to stay!"
United States
Chad
The price is ฿4,368
฿4,958 total
includes taxes & fees
7 Jun - 8 Jun
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hampton Inn Jacksonville East Regency Square

Hampton Inn Jacksonville East Regency Square
2.5 star property
12.8 km from Isle of Palms South
8.8 out of 10, Excellent, (1,010 reviews)
"Friendly staff !"
United States
TODD
The price is ฿3,144
฿3,569 total
includes taxes & fees
21 May - 22 May
Hampton Inn Jacksonville East Regency Square

Comfort Suites Baymeadows Near Butler Blvd

Comfort Suites Baymeadows Near Butler Blvd
3.0 star property
14.2 km from Isle of Palms South
8.4 out of 10, Very good, (1,009 reviews)
"The breakfast menu was fresh every morning the room was extra clean really enjoyed our stay we will return again the staff is wonderful."
United States
Theresa
The price is ฿3,132
฿3,555 total
includes taxes & fees
7 Jun - 8 Jun
Comfort Suites Baymeadows Near Butler Blvd

Fairfield Inn by Marriott Jacksonville Orange Park

Fairfield Inn by Marriott Jacksonville Orange Park
3.0 star property
27.9 km from Isle of Palms South
7.8 out of 10, Good, (740 reviews)
"This hotel is a decent place to stay."
United States
Dana
The price is ฿2,586
฿2,909 total
includes taxes & fees
8 Jun - 9 Jun
Fairfield Inn by Marriott Jacksonville Orange Park

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms South
9.6 out of 10, Exceptional, (100 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
The price is ฿4,622
฿5,246 total
includes taxes & fees
31 May - 1 Jun
TownePlace Suites by Marriott® Jacksonville Mayport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

Frequently asked questions

What is Isle of Palms South like?
Travellers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighbourhood.
How many hotels can I expect to find in Isle of Palms South?
With 11 Expedia hotels and other accommodation options in Isle of Palms South to choose from, this is a good starting point for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals in Isle of Palms South.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.