South Central Houston Travel Guide
Houston
Visit South Central Houston
Stay near popular South Central Houston attractions
Things to do
Houston: Space Center Houston Admission Ticket
฿1,002
per adult
92% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
฿402
per adult
80% of travellers recommend
Houston's Official City & Mural Tour!
฿1,504
per adult
88% of travellers recommend
Houston: Museum of Natural Science General Admission Ticket
฿837
per adult
98% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
฿3,647
per adult
92% of travellers recommend
Houston: Holocaust Museum Houston Entry Ticket
฿736
per adult
90% of travellers recommend
Top hotels in South Central Houston
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is ฿3,667 per night from 16 Aug to 17 Aug
฿3,667
฿4,329 total
16 Aug - 17 Aug
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
The price is ฿7,382 per night from 23 Jul to 24 Jul
฿7,382
฿9,844 total
23 Jul - 24 Jul
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,008 reviews)
"We were unable to leave the property for medical reasons so we ate at the hotel. The food was good but the menu was very limited. Shuttle service very good and fun ride. Beautiful pool area. Very nice hotel located close to Medical Center. Would stay there again!"
Reviewed on 21 Jul 2026
InterContinental Houston by IHG
6750 Main St Houston TX
The price is ฿4,770 per night from 25 Jul to 26 Jul
฿4,770
฿6,254 total
25 Jul - 26 Jul
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
The price is ฿6,019 per night from 24 Jul to 25 Jul
฿6,019
฿7,492 total
24 Jul - 25 Jul
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
The price is ฿4,108 per night from 26 Jul to 27 Jul
฿4,108
฿4,807 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
The price is ฿2,451 per night from 2 Aug to 3 Aug
฿2,451
฿2,877 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...
5.8/10 (1,004 reviews)
"The first room we walked in was on the second floor and I could smell the horrible smell before I even made it to the door. It’s smelled like something died so we had to switch rooms and we had a king suite which was downsized to a queen, the room was so small and compact. The tub was outdated it ..."
Reviewed on 20 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check South Central Houston hotel availability
Where to stay in South Central Houston
Find the best South Central Houston areas for the activities you enjoy most.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
