Santo Spirito Travel Guide
Florence





Visit Santo Spirito
Stay near popular Santo Spirito attractions
Things to do

City Sightseeing Florence Hop-on Hop-off Bus Tour

Florence: Reserved Entrance Ticket to the Medici Chapel

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Florence: Reserved Entry Ticket to Bargello Museum

Best of Florence Tour with David at Accademia & Duomo (with VIP option)
Top hotels in Santo Spirito

Hotel Horto Convento
"Everybody on staff was extremely helpful!"
Reviewed on 29 Aug 2026

La Torre Del Cestello

UNA Hotels Vittoria Firenze
"The entrance, the building, the lobby looked very well and promising. Room was small but ok. The shower was terrible, poor mainteined. Room decoration looked agressive. Breakfast was great. Location little far from downtown"
Reviewed on 6 Sept 2026

Casa Santo Nome di Gesù
"Beautiful hotel in great location. Staff really helpful with local knowledge. Communal fridge available at reception, which was great for storing drinks."
Reviewed on 27 Aug 2026

Palazzo Mannaioni Suites

Foresteria Valdese di Firenze - Casa per Ferie
"Rooms with AC, shops and laundromats within a block, incredible good restaurants at less than 10 minutes walk"
Reviewed on 1 Sept 2026
Where to stay in Santo Spirito

Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.























