Find hotels in Florence, SC from ฿2,200

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florence hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,258 reviews)
"Great stay!"
United States
Lisa
The price is ฿2,569
฿2,877 total
includes taxes & fees
25 May - 26 May
Park Inn by Radisson Florence, SC

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,000 reviews)
"One night stay"
United States
Dalet
The price is ฿3,964
฿4,439 total
includes taxes & fees
30 Apr - 1 May
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (898 reviews)
"Great staff. Great place to stay!"
United States
Debra
The price is ฿3,322
฿3,721 total
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Florence-North-I-95

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (982 reviews)
"Nice room and great breakfast "
United States
David
The price is ฿4,346
฿4,868 total
includes taxes & fees
3 May - 4 May
Staybridge Suites Florence - Civic Center by IHG

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,644 reviews)
"Great stay"
United States
Priscila
The price is ฿2,097
฿2,348 total
includes taxes & fees
26 Apr - 27 Apr
Howard Johnson by Wyndham Florence

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,261 reviews)
"I love this place I would stay again "
United States
Shunicee
The price is ฿3,438
฿3,851 total
includes taxes & fees
3 May - 4 May
Comfort Inn & Suites Florence Center Area

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (627 reviews)
"Great place to stay while we have long trip from FL to NY"
United States
Sergii
The price is ฿4,078
฿4,567 total
includes taxes & fees
3 May - 4 May
Fairfield Inn & Suites by Marriott Florence I-20

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very good, (683 reviews)
"comfortable beds, very clean"
United States
Xinbei
The price is ฿3,038
฿3,530 total
includes taxes & fees
10 May - 11 May
Homewood Suites by Hilton Florence

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1,001 reviews)
"It was clean and breakfast was good "
United States
Samina
The price is ฿3,142
฿3,632 total
includes taxes & fees
3 May - 4 May
Tru by Hilton Florence I-95

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was very friendly and helpful. Hotel was in a great location. Enjoyed our stay. Would definitely stay there again."
United States
Ann
The price is ฿3,928
฿4,399 total
includes taxes & fees
13 May - 14 May
Hyatt Place Florence Downtown

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (497 reviews)
"Jasmine at the front desk has been wonderful both times I’ve stayed! The rooms are clean, quiet, and comfortable. "
United States
Angelica
The price is ฿4,214
฿4,720 total
includes taxes & fees
9 May - 10 May
Hampton Inn & Suites Hartsville

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,000 reviews)
"Loved it … breakfast options great as well "
United States
Betsy
The price is ฿3,799
฿4,255 total
includes taxes & fees
24 May - 25 May
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,601 reviews)
"Very nice place to spend the night."
United States
Sharon
The price is ฿3,129
฿3,505 total
includes taxes & fees
3 May - 4 May
La Quinta Inn & Suites by Wyndham Florence

Quality Inn Dillon

Quality Inn Dillon
2.5 star property
Dillon
7.2 out of 10, Good, (798 reviews)
"It’s ok but the breakfast was good "
United States
RAJINDER
The price is ฿2,575
฿2,884 total
includes taxes & fees
26 Apr - 27 Apr
Quality Inn Dillon

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.2 out of 10, Very good, (80 reviews)
"Clean rooms. Helpful staff good location. It will be better if they offer better options in breakfast."
United States
TORAL
The price is ฿2,878
฿3,350 total
includes taxes & fees
3 May - 4 May
Spark by Hilton Florence North I-95, SC

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (809 reviews)
"Place was perfect for a short stay "
United States
Victor
The price is ฿3,804
฿4,260 total
includes taxes & fees
3 May - 4 May
TownePlace Suites by Marriott Florence

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
3.0 star property
Hartsville
8.6 out of 10, Excellent, (724 reviews)
"Went for a festival just across the street. Parked before checkin time, walked to restaurant. Great location. Front desk staff was very helpful and pleasant. Would definitely stay here again. Quite, clean, bed was comfortable. "
United States
Dawn
The price is ฿2,596
฿2,907 total
includes taxes & fees
8 May - 9 May
Fairfield Inn by Marriott Hartsville

Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (728 reviews)
"Very nice stay, quiet & clean. Staff was very nice as well. "
United States
Eric
The price is ฿3,123
฿3,498 total
includes taxes & fees
7 May - 8 May
Courtyard by Marriott Florence

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,000 reviews)
"For a roadside hotel it felt clean and pleasant. "
United States
Marianna
The price is ฿3,187
฿3,570 total
includes taxes & fees
3 May - 4 May
Best Western Inn

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1,001 reviews)
"The breakfast was great and the rooms were super comfortable "
United States
Jessica
The price is ฿3,170
฿3,807 total
includes taxes & fees
26 May - 27 May
Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Florence attractions

Florence and related destinations

Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Centre or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

Florence. Italy. Panorama of Florence on a sunny day.

Top Florence Hotel Reviews

More cheap stays in Florence

Frequently asked questions

What's the best place to stay in Florence?
Based on our traveller data, Park Inn by Radisson Florence, SC is one of the top choices for your stay. This hotel offers free breakfast and a 24-hour fitness centre. Other good options for your trip include Howard Johnson by Wyndham Florence and Comfort Inn & Suites Florence Center Area. See all available top hotels, or vacation rentals in Florence.
If I need to cancel my hotel reservation in Florence, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Florence.
What's the best accommodation for a budget-friendly stay in Florence?
Based on reviews, Park Inn by Radisson Florence, SC is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. Other good choices to stay on the cheap include Howard Johnson by Wyndham Florence and Days Inn by Wyndham Florence/I-95 North. View all budget hotels in Florence.
What's the best family accommodation in Florence?
Quality Inn & Suites Florence Civic Center is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other choices to stay with the children include Howard Johnson by Wyndham Florence and Spark by Hilton Florence North I-95, SC. Find more child-friendly accommodations in Florence.
What is the top LGBTQ-friendly place to stay in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are two other good options for your stay. See all available hotels listed as LGBTQ-friendly in Florence.
What's the best dog-friendly place to stay in Florence?
Park Inn by Radisson Florence, SC is a top hotel for people travelling with their pets, and offers a 24-hour fitness centre and free WiFi for its human guests. Other good options for you and your pet's trip include Comfort Inn & Suites Florence Center Area and Quality Inn & Suites Florence Civic Center. See more pet-friendly hotel accommodations in Florence.
What are some accommodation options with pools in Florence?
Hyatt Place Florence Downtown is a top hotel with an outdoor pool, free breakfast and free WiFi. A couple of other options that feature an on-site pool include Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG and Homewood Suites by Hilton Florence. View all hotels with pools in Florence.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness centre, a bar and a restaurant. Enjoy a facial, detox wrap or Swedish massage at the on-site spa. See all spa hotels in Florence.
What is staying in Florence like?
Families will find child-friendly activities in Florence, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its entertainment. In Florence, there are 133 hotels and other accommodation options to choose from. Find out more about Florence.
What are the top places to visit in Florence?
Landmarks like Mcleod Regional Medical Center, Florence National Cemetery and Florence Veterans Park might be worth a visit. A couple of additional sights to add to your itinerary are Florence Museum and Dr. Eddie Floyd Tennis Center. Take a look at what more there is to see and do in Expedia's Florence guide.
How can I get around Florence?
If you want to explore the larger area, take a train from Florence Station. If you want to venture out around the area, you may want a rental car in Florence for your journey.
What's the weather like in Florence?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.

Explore a world of travel with Expedia